Peer-Reviewed Publications Resulting from CHF-funded Grants
We invite you to learn about publications resulting from the Foundation's investments in research. One way CHF measures success in grantmaking is through the production of peer-reviewed publications. CHF-supported research has been published in 218 different peer-reviewed journals, including Nature Genetics and Science and frequently in journals such as the Journal of Veterinary Internal Medicine, Animal Genetics and the American Journal of Veterinary Research. By consistently funding the most innovative research, the AKC Canine Health Foundation is realizing both small milestones and major breakthroughs in canine health.
You may search the complete list of peer-reviewed publications by research program area, breed and/or disease associated with the grant.
To browse publications by year you may also wish to view our Impact Report.
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Grant Number: 00329-A Research Program Area: Neurology |
Genetics of Post-Squalene Cholesterol Biosynthesis in the Havanese, Akita and Samoyed: Are Defects in this Pathway Responsible for an Array of Developmental Abnormalities- A Pilot Study Starr, A. N., Famula, T. R., Markward, N. J., Baldwin, J. V., Fowler, K. D., Klumb, D. E., … Murphy, K. E. (2007). Hereditary Evaluation of Multiple Developmental Abnormalities in the Havanese Dog Breed. Journal of Heredity, 98(5), 510–517. https://doi.org/10.1093/jhered/esm049 |
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Grant Number: 00685-A Research Program Area: Immunology and Infectious Disease |
Standardization of Allergic Disease Serologic Testing with House Dust Mite Specific Canine lgE Monoclonal Antibodies Orton, S. M., Arasu, P., & Hammerberg, B. (2007). A novel gene from Brugia sp. that encodes a cytotoxic fatty acid binding protein allergen recognized by canine monoclonal IgE and serum IgE from infected dogs. Journal of Parasitology, 93(6), 1378–1387. https://doi.org/10.1645/GE-1217.1 |
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Grant Number: 00878-A Research Program Area: Oncology |
MicroRNA Expression in the Domestic Dog and Its Role in Canine Cancer Boggs, R. M., Moody, J. A., Long, C. R., Tsai, K. L., & Murphy, K. E. (2007). Identification, amplification and characterization of miR-17-92 from canine tissue. Gene, 404(1–2), 25–30. https://doi.org/10.1016/j.gene.2007.08.015 |
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Grant Number: 1407 Research Program Area: Epilepsy Initiative |
Idiopathic Epilepsy in Poodles: Determining Mode(s) of Inheritance Licht, B. G., Licht, M. H., Harper, K. M., Lin, S., Curtin, J. J., Hyson, L. L., & Willard, K. (2002). Clinical presentations of naturally occurring canine seizures: similarities to human seizures. Epilepsy & Behavior, 3(5), 460–470. https://doi.org/10.1016/S1525-5050(02)00523-1
Licht, B. G., Lin, S., Luo, Y., Hyson, L. L., Licht, M. H., Harper, K. M., … Johnston, E. V. (2007). Clinical characteristics and mode of inheritance of familial focal seizures in Standard Poodles. Journal of the American Veterinary Medical Association, 231(10), 1520–1528. https://doi.org/10.2460/javma.231.10.1520
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Grant Number: 00326-A Research Program Area: General Canine Health |
Microphthalmia, Merle and MITF in Dogs Schmutz, S. M., & Berryere, T. G. (2007). Genes affecting coat colour and pattern in domestic dogs: a review: Coat colour genes in dogs. Animal Genetics, 38(6), 539–549. https://doi.org/10.1111/j.1365-2052.2007.01664.x |
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Grant Number: 198 Research Program Area: Neurology |
Hereditary Ceroid Lipofuscinosis in Tibetan Terriers Awano, T., Katz, M. L., O’Brien, D. P., Sohar, I., Lobel, P., Coates, J. R., … Johnson, G. S. (2006). A frame shift mutation in canine TPP1 (the ortholog of human CLN2) in a juvenile Dachshund with neuronal ceroid lipofuscinosis. Molecular Genetics and Metabolism, 89(3), 254–260. https://doi.org/10.1016/j.ymgme.2006.02.016
Awano, T., Katz, M. L., O’Brien, D. P., Taylor, J. F., Evans, J., Khan, S., … Johnson, G. S. (2006). A mutation in the cathepsin D gene (CTSD) in American Bulldogs with neuronal ceroid lipofuscinosis. Molecular Genetics and Metabolism, 87(4), 341–348. https://doi.org/10.1016/j.ymgme.2005.11.005
Katz, M. L., Sanders, D. N., Mooney, B. P., & Johnson, G. S. (2007). Accumulation of glial fibrillary acidic protein and histone H4 in brain storage bodies of Tibetan Terriers with hereditary neuronal ceroid lipofuscinosis. Journal of Inherited Metabolic Disease, 30(6), 952–963. https://doi.org/10.1007/s10545-007-0683-y
Katz, Martin L., Narfstrom, K., Johnson, G. S., & O’Brien, D. P. (2005). Assessment of retinal function and characterization of lysosomal storage body accumulation in the retinas and brains of Tibetan Terriers with ceroid-lipofuscinosis. American Journal of Veterinary Research, 66(1), 67–76. https://doi.org/10.2460/ajvr.2005.66.67 |
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Grant Number: 00696-A Research Program Area: Hepatic Disease |
Transplenic Portography Using a Single Detector Helical CT: Comparison With Transplenic Portal Scintigraphy and Dual Phase CT Angiography Sura, P. A., Tobias, K. M., Morandi, F., Daniel, G. B., & Echandi, R. L. (2007). Comparison of 99m TcO 4 ? Trans-Splenic Portal Scintigraphy with Per-Rectal Portal Scintigraphy for Diagnosis of Portosystemic Shunts in Dogs. Veterinary Surgery, 36(7), 654–660. https://doi.org/10.1111/j.1532-950X.2007.00317.x |
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Grant Number: 00757B Research Program Area: Oncology - Osteosarcoma |
Hereditary Mutations in Genes Associated with Osteosarcoma in Large Dog Breeds Karlsson, E. K., Baranowska, I., Wade, C. M., Salmon Hillbertz, N. H. C., Zody, M. C., Anderson, N., … Lindblad-Toh, K. (2007). Efficient mapping of mendelian traits in dogs through genome-wide association. Nature Genetics, 39(11), 1321–1328. https://doi.org/10.1038/ng.2007.10 |
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Grant Number: 00584-A Research Program Area: Dermatology and Allergic Disease |
Lethal Acrodermatitis in Bull Terriers: Using Proteomic Techniques to Identify the Genetic Defect Grider, A., Mouat, M. F., Mauldin, E. A., & Casal, M. L. (2007). Analysis of the liver soluble proteome from Bull Terriers affected with inherited lethal acrodermatitis. Molecular Genetics and Metabolism, 92(3), 249–257. https://doi.org/10.1016/j.ymgme.2007.07.003 |
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Grant Number: 2250 Research Program Area: Cardiology |
Diet-Related Taurine Deficiency in Newfoundland Dogs and Associated Cardiac Insufficiency Backus, R. C., Cohen, G., Pion, P. D., Good, K. L., Rogers, Q. R., & Fascetti, A. J. (2003). Taurine deficiency in Newfoundlands fed commercially available complete and balanced diets. Journal of the American Veterinary Medical Association, 223(8), 1130–1136. https://doi.org/10.2460/javma.2003.223.1130
Backus, R. C., Ko, K. S., Fascetti, A. J., Kittleson, M. D., MacDonald, K. A., Maggs, D. J., … Rogers, Q. R. (2006). Low Plasma Taurine Concentration in Newfoundland Dogs is Associated with Low Plasma Methionine and Cyst(e)ine Concentrations and Low Taurine Synthesis. The Journal of Nutrition, 136(10), 2525–2533. https://doi.org/10.1093/jn/136.10.2525 |
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Grant Number: 366 Research Program Area: Oncology |
Molecular Control of COX-2 Expression and Regulation of Prostaglandin Transport in Canine Mammary Tumors Brunelle, M., Sartin, E. A., Wolfe, L. G., Sirois, J., & Doré, M. (2006). Cyclooxygenase-2 Expression in Normal and Neoplastic Canine Mammary Cell Lines. Veterinary Pathology, 43(5), 656–666. https://doi.org/10.1354/vp.43-5-656 |
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Grant Number: 2044 Research Program Area: Endocrinology |
Ultrasonic and Cytologic Evaluation of the Thyroid Gland in Golden Retriever Dogs Bromel, C., Pollard, R. E., Kass, P. H., Samii, V. F., Davidson, A. P., & Nelson, R. W. (2005). Ultrasonographic Evaluation of the Thyroid Gland in Healthy, Hypothyroid, and Euthyroid Golden Retrievers with Nonthyroidal Illness. Journal of Veterinary Internal Medicine, 19, 499–506.
Brömel, C., Samii, V. F., Davidson, A. P., & Nelson, R. W. (2006). Comparison of ultrasonographic characteristics of the thyroid gland in healthy small-, medium-, and large-breed dogs. American Journal of Veterinary Research, 67(1), 8.
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Grant Number: 00360-A Research Program Area: Cardiology |
Genome Expression Profiling: Canine Cardiomyopathy and Degenerative Mitral Valve Disease Oyama, M. A., & Chittur, S. V. (2006). Genomic expression patterns of mitral valve tissues from dogs with degenerative mitral valve disease. American Journal of Veterinary Research, 67(8), 1307–1318. https://doi.org/10.2460/ajvr.67.8.1307 |
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Grant Number: 440 Research Program Area: Cardiology |
A Molecular Evaluation of Two Forms of Canine Cardiomyopathy
Parker, H. G., Meurs, K. M., & Ostrander, E. A. (2006). Finding cardiovascular disease genes in the dog. Journal of Veterinary Cardiology, 8(2), 115–127. https://doi.org/10.1016/j.jvc.2006.04.002
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Grant Number: 2226 Research Program Area: Endocrinology |
Characterizing the Inheritance of Addison's Disease and Linked DNA Markers Famula, T. R., Belanger, J. M., & Oberbauer, A. M. (2003). Heritability and complex segregation analysis of hypoadrenocorticism in the Standard Poodle. Journal of Small Animal Practice, 44(1), 8–12. https://doi.org/10.1111/j.1748-5827.2003.tb00096.x
Oberbauer, A., Bell, J., Belanger, J., & Famula, T. (2006). Genetic evaluation of Addison’s disease in the Portuguese Water Dog. BMC Veterinary Research, 2(15), 7. https://doi.org/doi:10.1186/1746-6148-2-15
Oberbauer, A. M., Benemann, K. S., Belanger, J. M., Wagner, D. R., Ward, J. H., & Famula, T. R. (2002). Inheritance of hypoadrenocorticism in Bearded Collies. American Journal of Veterinary Research, 63(5), 643–647. https://doi.org/10.2460/ajvr.2002.63.643
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Help Future Generations of Dogs
Participate in canine health research by providing samples or by enrolling in a clinical trial. Samples are needed from healthy dogs and dogs affected by specific diseases.
Help Future Generations of Dogs
Participate in canine health research by providing samples or by enrolling in a clinical trial. Samples are needed from healthy dogs and dogs affected by specific diseases.
