00696-A: Transplenic Portography Using a Single Detector Helical CT: Comparison With Transplenic Portal Scintigraphy and Dual Phase CT Angiography

Grant Status: Closed

Grant Amount: $8,694
Dr. Rita Echandi, DVM, University of Tennessee
January 1, 2006 - December 31, 2006
Breed(s): -All Dogs
Research Program Area: Treatment

Abstract

Being able to evaluate the vascular anatomy of the liver is important in dogs because of the frequent occurrence of portosystemic shunts. Portosystemic shunts are anomalous blood vessels that create an abnormal communication between the portal vein and the general circulation (caudal vena cava). When a portosystemic shunt is present, this abnormal blood vessel allows the portal blood to enter the caudal vena cava before it goes to the liver. This causes a build up of toxins within the body that has detrimental effects on the dog. In general, large dogs are more likely to have intrahepatic PSS while toy breeds tend to have extrahepatic PSS. Morbidity and mortality are higher for intrahepatic compared to extrahepatic PSS. Several invasive and non-invasive imaging modalities have been used to evaluate hepatic vascular anatomy. The advantage of knowing the exact location of the shunt and therefore have adequate planning would outweigh the risk of an additional anesthetic episode. This study aims to compare transplenic portal scintigraphy and dual phase CT angiography, evaluate contrast patterns and create a 3D anatomical reference to aide in the surgical repair of PSS in dogs.

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