Peer-Reviewed Publications Resulting from CHF-funded Grants
We invite you to learn about publications resulting from the Foundation's investments in research. One way CHF measures success in grantmaking is through the production of peer-reviewed publications. CHF-supported research has been published in 218 different peer-reviewed journals, including Nature Genetics and Science and frequently in journals such as the Journal of Veterinary Internal Medicine, Animal Genetics and the American Journal of Veterinary Research. By consistently funding the most innovative research, the AKC Canine Health Foundation is realizing both small milestones and major breakthroughs in canine health.
You may search the complete list of peer-reviewed publications by research program area, breed and/or disease associated with the grant.
To browse publications by year you may also wish to view our Impact Report.
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Grant Number: 00338-A Research Program Area: Dermatology and Allergic Disease |
Does Melatonin Result in Hair Regrowth in Dogs with Follicular Arrest (Alopecia X) by Blocking Estrogen Receptors on Hair Follicles? Frank, L. A., Donnell, R. L., & Kania, S. A. (2006). Oestrogen receptor evaluation in Pomeranian dogs with hair cycle arrest (alopecia X) on melatonin supplementation. Veterinary Dermatology, 17(4), 252–258. https://doi.org/10.1111/j.1365-3164.2006.00520.x |
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Grant Number: 00325-A Research Program Area: Musculoskeletal Conditions and Disease |
A Candidate Gene Approach for Skeletal Dysplasia in the Newfoundland, Chesapeake Bay Retriever and Nova Scotia Duck Tolling Retriever Young, A. E., Ryun, J. R., & Bannasch, D. L. (2006). Deletions in the COL10A1 gene are not associated with skeletal changes in dogs. Mammalian Genome, 17(7), 761–768. https://doi.org/10.1007/s00335-005-0163-3 |
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Grant Number: 0001729 Research Program Area: Epilepsy Initiative |
Canine Epilepsy: Determining the Mode of Inheritance, Mapping the Genes, and Developing Linkage Test Patterson, E. E., Armstrong, P. J., O’Brien, D. P., Roberts, M. C., Johnson, G. S., & Mickelson, J. R. (2005). Clinical description and mode of inheritance of idiopathic epilepsy in English Springer Spaniels. Journal of the American Veterinary Medical Association, 226(1), 54–58. https://doi.org/10.2460/javma.2005.226.54 Patterson, E. E., Mickelson, J. R., Da, Y., Roberts, M. C., McVey, A. S., O’Brien, D. P., … Armstrong, P. J. (2003). Clinical Characteristics and Inheritance of Idiopathic Epilepsy in Vizslas. Journal of Veterinary Internal Medicine, 17, 319–325. |
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Grant Number: 1845 Research Program Area: Epilepsy Initiative |
Molecular Genetic Causes of Canine Epilepsies O’Brien, D. P. (2005). Genetic Mapping of Canine Multiple System Degeneration and Ectodermal Dysplasia Loci. Journal of Heredity, 96(7), 727–734. https://doi.org/10.1093/jhered/esi086
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Grant Number: 2036 Research Program Area: Neurology |
Hereditary Ceroid Lipofuscinosis in Dogs Evans, J., Katz, M. L., Levesque, D., Shelton, G. D., de Lahunta, A., & O’Brien, D. (2005). A Variant Form of Neuronal Ceroid Lipofuscinosis in American Bulldogs. Journal of Veterinary Internal Medicine, 19, 44–51.
Katz, M. L., Khan, S., Awano, T., Shahid, S. A., Siakotos, A. N., & Johnson, G. S. (2005). A mutation in the CLN8 gene in English Setter dogs with neuronal ceroid-lipofuscinosis. Biochemical and Biophysical Research Communications, 327(2), 541–547. https://doi.org/10.1016/j.bbrc.2004.12.038
Katz, M. L., Sanders, D. A., Sanders, D. N., Hansen, E. A., & Johnson, G. S. (2002). Assessment of plasma carnitine concentrations in relation to ceroid lipofuscinosis in Tibetan Terriers. American Journal of Veterinary Research, 63(6), 890–895. https://doi.org/10.2460/ajvr.2002.63.890 |
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Grant Number: 2264 Research Program Area: General Canine Health |
Whole Genome Screens Using Microsatellite Markers in Genetic Analyses of Hereditary Deafness in the Dalmatian and English Setter Cargill, E. J. (2004). Heritability and Segregation Analysis of Deafness in U.S. Dalmatians. Genetics, 166(3), 1385–1393. https://doi.org/10.1534/genetics.166.3.1385 Cargill, Edward J, Famula, T. R., Schnabel, R. D., Strain, G. M., & Murphy, K. E. (2005). The color of a Dalmatian’s spots: Linkage evidence to support the TYRP1 gene. BMC Veterinary Research, 1(1), 3. Cargill, E.J., Schnabel, R. D., & Murphy, K. E. (2004). Assignment of Canine MSS1 Microsatellite Markers to Chromosomes by Linkage Data. DNA Sequence, 15(3), 209–212. https://doi.org/10.1080/10425170410001704490 |
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Grant Number: 249 Research Program Area: Oncology |
Genomics of Canine Brain Neoplasia Thomson, S. A. M., Kennerly, E., Olby, N., Mickelson, J. R., Hoffmann, D. E., Dickinson, P. J., … Breen, M. (2005). Microarray Analysis of Differentially Expressed Genes of Primary Tumors in the Canine Central Nervous System. Veterinary Pathology, 42(5), 550–558. https://doi.org/10.1354/vp.42-5-550
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Grant Number: 1432 Research Program Area: Immunology and Infectious Disease |
The Genetics of the Major Histocompatibility Complex in Canine Immune-Mediated Disease Angles, J. M., Kennedy, L. J., & Pedersen, N. C. (2005). Frequency and distribution of alleles of canine MHC-II DLA-DQB1, DLA-DQA1 and DLA-DRB1 in 25 representative American Kennel Club breeds. Tissue Antigens, 66(3), 173–184. https://doi.org/10.1111/j.1399-0039.2005.00461.x
Kennedy, L. J., Altet, L., Angles, J. M., Barnes, A., Carter, S. D., Francino, O., … Wagner, J. L. (2000). Nomenclature for factors of the Dog Major Histocompatibility System (DLA), 1998: first report of the ISAG DLA Nomenclature Committee. Animal Genetics, 10. |
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Grant Number: 2628 Research Program Area: Musculoskeletal Conditions and Disease |
The Effects of Acupuncture, Electroacupuncture and Transcutaneous Cranial Electrical Stimulation on Isoflurane Requirements in Dogs: A Comparative Study Culp, L. B., Skarda, R. T., & Muir III, W. W. (2005). Comparisons of the effects of acupuncture, electroacupuncture, and transcutaneous cranial electrical stimulation on the minimum alveolar concentration of isoflurane in dogs. American Journal of Veterinary Research, 66(8), 1364–1370. https://doi.org/10.2460/ajvr.2005.66.1364 |
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Grant Number: 2002 Research Program Area: Cardiology |
Evaluation of the Clinical Outcome of Asymptomatic Adult Boxers with Ventricular Arrythmias Over a Four-Year Period Baumwart, R. D., & Meurs, K. M. (2005). Assessment of plasma brain natriuretic peptide concentration in Boxers with arrhythmogenic right ventricular cardiomyopathy. American Journal of Veterinary Research, 66(12), 2086–2089. https://doi.org/10.2460/ajvr.2005.66.2086
Baumwart, R. D., Meurs, K. M., Atkins, C. E., Bonagura, J. D., DeFrancesco, T. C., Keene, B. W., … Spier, A. W. (2005). Clinical, echocardiographic, and electrocardiographic abnormalities in Boxers with cardiomyopathy and left ventricular systolic dysfunction: 48 cases (1985-2003). Journal of the American Veterinary Medical Association, 226(7), 1102–1104. https://doi.org/10.2460/javma.2005.226.1102
Meurs, K. M., Spier, A. W., Wright, N. A., & Hamlin, R. L. (2001). Use of ambulatory electrocardiography for detection of ventricular premature complexes in healthy dogs. Journal of the American Veterinary Medical Association, 218(8), 1291–1292. https://doi.org/10.2460/javma.2001.218.1291 |
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Grant Number: 2032 Research Program Area: General Canine Health |
Y-Chromosome Haplotype Analysis in the Dog Bannasch, D. L., Bannasch, M. J., Ryun, J. R., Famula, T. R., & Pedersen, N. C. (2005). Y chromosome haplotype analysis in purebred dogs. Mammalian Genome, 16(4), 273–280. https://doi.org/10.1007/s00335-004-2435-8 |
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Grant Number: 2105 Research Program Area: Oncology |
Characterization of Host and Environmental Risk Factors for Urinary Bladder Cancer in a High Risk Breed (the Scottish Terrier) Glickman, L. T., Raghavan, M., Knapp, D. W., Bonney, P. L., & Dawson, M. H. (2004). Herbicide exposure and the risk of transitional cell carcinoma of the urinary bladder in Scottish Terriers. Journal of the American Veterinary Medical Association, 224(8), 1290–1297. https://doi.org/10.2460/javma.2004.224.1290
Raghavan, M., Knapp, D. W., Bonney, P. L., Dawson, M. H., & Glickman, L. T. (2005). Evaluation of the effect of dietary vegetable consumption on reducing risk of transitional cell carcinoma of the urinary bladder in Scottish Terriers. Journal of the American Veterinary Medical Association, 227(1), 94–100. https://doi.org/10.2460/javma.2005.227.94 |
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Grant Number: 454 Research Program Area: Gastrointestinal Disease |
Analysis of a Candidate Gene for Pancreatic Acinar Atrophy in the German Shepherd Dog Clark, L. A., Wahl, J. M., Steiner, J. M., Zhou, W., Ji, W., Famula, T. R., … Murphy, K. E. (2005). Linkage analysis and gene expression profile of pancreatic acinar atrophy in the German Shepherd Dog. Mammalian Genome, 16(12), 955–962. https://doi.org/10.1007/s00335-005-0076-1
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Grant Number: 1656 Research Program Area: Cardiology |
Cellular, Biochemical and Molecular Biological Analysis of Dilated Cardiomyopathy in Portuguese Water Dogs Alroy, J., Rush, J. E., & Sarkar, S. (2005). Infantile dilated cardiomyopathy in Portuguese water dogs: Correlation of the autosomal recessive trait with low plasma taurine at infancy. Amino Acids, 28(1), 51–56. https://doi.org/10.1007/s00726-004-0149-6 |
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Grant Number: 002304 Research Program Area: Epilepsy Initiative |
Continued Investigation into the Molecular Genetic Causes of Canine Epilepsies O’Brien, D. P. (2005). Genetic Mapping of Canine Multiple System Degeneration and Ectodermal Dysplasia Loci. Journal of Heredity, 96(7), 727–734. https://doi.org/10.1093/jhered/esi086 |
Help Future Generations of Dogs
Participate in canine health research by providing samples or by enrolling in a clinical trial. Samples are needed from healthy dogs and dogs affected by specific diseases.
Help Future Generations of Dogs
Participate in canine health research by providing samples or by enrolling in a clinical trial. Samples are needed from healthy dogs and dogs affected by specific diseases.
