Peer-Reviewed Publications Resulting from CHF-funded Grants

We invite you to learn about publications resulting from the Foundation's investments in research. One way CHF measures success in grantmaking is through the production of peer-reviewed publications. CHF-supported research has been published in 218 different peer-reviewed journals, including Nature Genetics and Science and frequently in journals such as the Journal of Veterinary Internal Medicine, Animal Genetics and the American Journal of Veterinary Research.  By consistently funding the most innovative research, the AKC Canine Health Foundation is realizing both small milestones and major breakthroughs in canine health.

You may search the complete list of peer-reviewed publications by research program area, breed and/or disease associated with the grant.

To browse publications by year you may also wish to view our Impact Report.

Research Program Area
Breed:
Disease:
 
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Grant Number: 00664-A

Research Program Area: Oncology

Exploration of Alternative Samples for Prognostic Assay of Canine Cancers: Getting the Most Out of Existing Samples and Testing New Ones Collected Without Surgery
Starkey, M. P., & Murphy, S. (2010). Using lymph node fine needle aspirates for gene expression profiling of canine lymphoma. Veterinary and Comparative Oncology, 8(1), 56–71. https://doi.org/10.1111/j.1476-5829.2009.00205.x

Grant Number: 00567-A

Research Program Area: Ophthalmology

Mapping the Genetic Lesion of Primary Lens Luxation in Lancashire Heelers, Miniature Bull Terriers and Other Terrier Breeds
Farias, F. H. G., Johnson, G. S., Taylor, J. F., Giuliano, E., Katz, M. L., Sanders, D. N., … Mellersh, C. (2010). An ADAMTS17 Splice Donor Site Mutation in Dogs with Primary Lens Luxation. Investigative Ophthalmology & Visual Science, 51(9), 4716–4721. https://doi.org/10.1167/iovs.09-5142
 
Sargan, D. R., Withers, D., Pettitt, L., Squire, M., Gould, D. J., & Mellersh, C. S. (2007). Mapping the Mutation Causing Lens Luxation in Several Terrier Breeds. Journal of Heredity, 98(5), 534–538. https://doi.org/10.1093/jhered/esm029

Grant Number: 00990-A

Research Program Area: Oncology

Prognostic Indicators for Anal Sac Gland Carcinoma in the English Cocker Spaniel and Preparing to Map Predisposition to this Tumor
Aguirre-Hernández, J., Polton, G., Kennedy, L. J., & Sargan, D. R. (2010). Association between anal sac gland carcinoma and dog leukocyte antigen-DQB1 in the English Cocker Spaniel. Tissue Antigens, 76(6), 476–481. https://doi.org/10.1111/j.1399-0039.2010.01554.x

Grant Number: 01186-A

Research Program Area: Musculoskeletal Conditions and Disease

Evaluation of the Soft Tissue Compartments of the Canine Manus
Ober, C. P., Jones, J. C., Larson, M. M., & Lanz, O. I. (2010). Computed tomographic and cross-sectional anatomic characterization of myofascial compartments and soft tissue spaces in the manus in cadavers of dogs without forelimb disease. American Journal of Veterinary Research, 71(2), 138–149. https://doi.org/10.2460/ajvr.71.2.138
 
Ober, C. P., Jones, J. C., Larson, M. M., Lanz, O. I., & Werre, S. R. (2010). Modeling of the spread of infection in the interdigital spaces of the manus in limbs from clinically normal dogs. American Journal of Veterinary Research, 71(3), 268–274. https://doi.org/10.2460/ajvr.71.3.268

Grant Number: 01074-A

Research Program Area: Gastrointestinal Disease

The Role of Enteropathogenic Bacteria in Diarrhea in Racing Alaskan Sled Dogs
McKenzie, E., Lupfer, C., Banse, H., Hinchcliff, K., Love, S., Nelson, Jr, S., … Pastey, M. (2010). Hypogammaglobulinemia in Racing Alaskan Sled Dogs. Journal of Veterinary Internal Medicine, 24(1), 179–184. https://doi.org/10.1111/j.1939-1676.2009.0416.x
 
McKenzie, E., Riehl, J., Banse, H., Kass, P. H., Nelson, Jr, S., & Marks, S. L. (2010). Prevalence of Diarrhea and Enteropathogens in Racing Sled Dogs. Journal of Veterinary Internal Medicine, 24(1), 97–103. https://doi.org/10.1111/j.1939-1676.2009.0418.x

Grant Number: 1099

Research Program Area: Neurology

Degenerate PCR for Detection of Viral, Bacterial, and Rickettsial Genera in Pugs and Maltese Dogs with Necrotizing and Granulomatous Meningoencephalitis
Barber, R. M., Li, Q., Diniz, P. P. V. P., Porter, B. F., Breitschwerdt, E. B., Claiborne, M. K., … Schatzberg, S. J. (2010). Evaluation of Brain Tissue or Cerebrospinal Fluid with Broadly Reactive Polymerase Chain Reaction for Ehrlichia, Anaplasma , Spotted Fever Group Rickettsia, Bartonella, and Borrelia Species in Canine Neurological Diseases (109 Cases). Journal of Veterinary Internal Medicine, 24(2), 372–378. https://doi.org/10.1111/j.1939-1676.2009.0466.x
 
Nghiem, P. P., & Schatzberg, S. J. (2010). Conventional and molecular diagnostic testing for the acute neurologic patient. Journal of Veterinary Emergency and Critical Care, 20(1), 46–61. https://doi.org/doi:10.1111/j.1476-4431.2009.00495.x
 
Schatzberg, S. J., Li, Q., Porter, B. F., Barber, R. M., Claiborne, M. K., Levine, J. M., … Tong, S. (2009). Broadly Reactive Pan-Paramyxovirus Reverse Transcription Polymerase Chain Reaction and Sequence Analysis for the Detection of Canine Distemper Virus in a Case of Canine Meningoencephalitis of Unknown Etiology. Journal of Veterinary Diagnostic Investigation, 21(6), 844–849. https://doi.org/10.1177/104063870902100613
 
Talarico, L. R., & Schatzberg, S. J. (2010). Idiopathic granulomatous and necrotising inflammatory disorders of the canine central nervous system: A review and future perspectives. Journal of Small Animal Practice, 51(3), 138–149. https://doi.org/10.1111/j.1748-5827.2009.00823.x

Grant Number: 01179-A

Research Program Area: General Canine Health

Evaluation of Fungal Flora in Normal and Diseased Canine Ears
Campbell, J. J., Coyner, K. S., Rankin, S. C., Lewis, T. P., Schick, A. E., & Shumaker, A. K. (2010). Evaluation of fungal flora in normal and diseased canine ears. Veterinary Dermatology, 21(6), 619–625. https://doi.org/10.1111/j.1365-3164.2010.00927.x

Grant Number: 2010

Research Program Area: Oncology

Dissecting the Biology and Genetics of c-Kit Mutations in Canine Mast Cell Tumors

Downing, S., Chien, M. B., Kass, P. H., Moore, P. F., & London, C. A. (2002). Prevalence and importance of internal tandem duplications in exons 11 and 12 of c- kit in mast cell tumors of dogs. American Journal of Veterinary Research, 63(12), 1718–1723. https://doi.org/10.2460/ajvr.2002.63.1718

Lin, T.-Y., Fenger, J., Murahari, S., Bear, M. D., Kulp, S. K., Wang, D., … London, C. A. (2010). AR-42, a novel HDAC inhibitor, exhibits biologic activity against malignant mast cell lines via down-regulation of constitutively activated Kit. Blood, 115(21), 4217–4225. https://doi.org/10.1182/blood-2009-07-231985

Grant Number: 00985-A

Research Program Area: Ophthalmology

In vivo Effects of Tetracycline on Canine Refractory Ulcers
Chandler, H. L., Gemensky-Metzler, A. J., Bras, I. D., Robbin-Webb, T. E., Saville, W. J. A., & Colitz, C. M. H. (2010). In vivo effects of adjunctive tetracycline treatment on refractory corneal ulcers in dogs. Journal of the American Veterinary Medical Association, 237(4), 378–386. https://doi.org/10.2460/javma.237.4.378

Grant Number: 00886-A

Research Program Area: Epilepsy Initiative

Oral Pregabalin as an Add-on Therapy for Refractory Idopathic Epilepsy in Dogs

Dewey, C. W., Cerda-Gonzalez, S., Levine, J. M., Badgley, B. L., Ducoté, J. M., Silver, G. M., … Lavely, J. A. (2009). Pregabalin as an adjunct to phenobarbital, potassium bromide, or a combination of phenobarbital and potassium bromide for treatment of dogs with suspected idiopathic epilepsy. Journal of the American Veterinary Medical Association, 235(12), 1442–1449. https://doi.org/10.2460/javma.235.12.1442

Grant Number: 763

Research Program Area: Ophthalmology

Capsular Tension Ring Effect on Canine Lens Epithelial Migration and Post-Operative Lens Capsule Opacification
Wilkie, D. A., & Colitz, C. M. (2009). Update on veterinary cataract surgery: Current Opinion in Ophthalmology, 20(1), 61–68. https://doi.org/10.1097/ICU.0b013e32831a98aa

Grant Number: 00997-A

Research Program Area: Ophthalmology

Virological Survey of Dogs with Idiopathic Conjunctivitis
Ledbetter, E. C., Hornbuckle, W. E., & Dubovi, E. J. (2009). Virologic survey of dogs with naturally acquired idiopathic conjunctivitis. Journal of the American Veterinary Medical Association, 235(8), 954–959. https://doi.org/10.2460/javma.235.8.954

Grant Number: 1276

Research Program Area: Kidney & Urological Disease

Molecular Genetic Characterization of Canine Cystinuria for the Development of Carrier Tests
Bannasch, D., & Henthorn, P. S. (2009). Changing Paradigms in Diagnosis of Inherited Defects Associated with Urolithiasis. Veterinary Clinics of North America: Small Animal Practice, 39(1), 111–125. https://doi.org/10.1016/j.cvsm.2008.09.006

Grant Number: 00849-A

Research Program Area: Reproductive Conditions

Incidence of Serum Alloantibody in Dogs with a Known History of Pregnancy
Blais, M.-C., Rozanski, E. A., Hale, A. S., Shaw, S. P., & Cotter, S. M. (2009). Lack of Evidence of Pregnancy-Induced Alloantibodies in Dogs. Journal of Veterinary Internal Medicine, 23(3), 462–465. https://doi.org/10.1111/j.1939-1676.2009.0286.x

Grant Number: 00906-A

Research Program Area: Epilepsy Initiative

Development of Pharmacogenetic Markers for Refractoriness to Phenobarbital in Treatment of Canine Epilepsy
Kennerly, E. M., Idaghdour, Y., Olby, N. J., Munana, K. R., & Gibson, G. (2009). Pharmacogenetic association study of 30 genes with phenobarbital drug response in epileptic dogs: Pharmacogenetics and Genomics, 19(12), 911–922. https://doi.org/10.1097/FPC.0b013e3283307cba

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