Hemangiosarcoma Research Initiative

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|What is Hemangiosarcoma?| Why Study it?| CHF Studies | AKC Match Challenge | Publications | Webinars | Sponsors of the Hemangiosarcoma Initiative |

What is Hemangiosarcoma? 

  • An aggressive and common cancer in dogs.
  • While the cause of the disease is unknown, certain breeds (Golden Retriever, Portuguese Water Dog, Boxer, German Shepherd Dog) are considered to be high-risk. This suggests that heritable traits, while not singularly responsible, may contribute to the disease.
  • Hemangiosarcoma can develop in any tissue or organ, but the most common primary sites for these tumors include spleen, right atrium of the heart, and the skin.

Why study it? 

  • While cutaneous masses (affecting the skin) are often treatable by tumor excision, tumors affecting internal organs are associated with poorer prognosis and are almost always incurable.
  • Hemangiosarcoma is often called the “silent killer” because the tumors are often not detected until the later stages of the disease, and even dogs harboring large tumors may show no clinical signs or evidence that they have a life threatening disease.
  • Because treatments have not improved the overall survival times for dogs with this disease, tremendous efforts are being made through research funded by the CHF and its donors to gain a better understanding of the biology and progression of this disease with the goal to design new and effective approaches to treatment.

CHF Studies: 

02217: A Novel Mechanism to Regulate the Growth of Canine Hemangiosarcoma
Principal Investigator: Erin B. Dickerson, PhD; University of Minnesota
Total Grant Amount: $86,206.00; Grant Period: 1/1/2016 - 6/30/2018

02234-MOU: A Novel Approach for Prevention of Canine Hemangiosarcoma
Principal Investigator: Jaime F Modiano, VMD, PhD; University of Minnesota
Total Grant Amount: $432,000.00; Grant Period: 3/1/2016 - 2/28/2019

02519: Prevalence of Bartonella spp. Infection in Dogs with Cardiac and Splenic Hemangiosarcomas within and between Geographic Locations
Principal Investigator: Edward B Breitschwerdt, DVM; Matthew Breen, PhD; North Carolina State University
Total Grant Amount: $219,026.00; Grant Period: 2/1/2018 - 1/31/2020

02510: Identification of Novel Synthetic Lethal Partners to Optimize PI3K Targeted Therapies in Canine Hemangiosarcoma
Principal Investigator: Cheryl A. London, DVM PhD; Tufts Medical Center
Total Grant Amount: $168,857; Grant Period: 3/1/2018 - 2/28/2021 

 

AKC Match Challenge

You’ve helped us meet the $250,000 AKC Hemangiosarcoma match!

GOOD NEWS! The American German Shepherd Dog Charitable Foundation will generously extend the hemangiosarcoma match with a pledge of $33,500 in matched funds.

Already in 2018, the American Kennel Club matched $250,000 in donations, the Golden Retriever Foundation matched $50,000 in donations, and the Flat-Coated Retriever Foundation matched $25,000 in donations. Thanks to the generosity of these organizations and our donors, $358,500 in donations to hemangiosarcoma research will be matched!

 

 

Publications on Hemangiosarcoma from CHF Studies:

 

Webinars:

Prevention Strategies for Canine Hemangiosarcoma?

See what Douglas H. Thamm, VMD, DACVIM (Oncology) has to say about cancer prevention as well as what we know about the connection between the use of vaccines, flea, tick and heartworm preventatives and cancer risk in dogs.

Update on Canine Hemangiosarcoma

Douglas H. Thamm, VMD, DACVIM (Oncology) presents on:

  •     The clinical presentation, staging, therapy and prognosis in canine hemangiosarcoma
  •     Recent findings about the biology of the disease
  •     Early diagnosis and new treatment strategies
 

Thank you to the sponsors of the Hemangiosarcoma Initiative!

Champion Sponsors ($50,000+)

 

 

 

 

 

Sponsors ($2,500+)

Alaskan Malamute Club of America, Inc.
American Belgian Tervuren Club, Inc.
American Bloodhound Club
American Bullmastiff Association
American Pointer Club
Australian Shepherd Health & Genetics Institute, Inc.
Australian Terrier Trust
Basset Hound Club of America, Inc.
Bedlington Terrier Club of America
Bernese Mountain Dog Club of America
Bouvier Health Foundation
Briard Club of America Health & Education Trust
Chesapeake Kennel Club of Maryland, Inc.
Clumber Spaniel Health Foundation
Dachshund Club of America, Inc.
Flat-Coated Retriever Foundation

French Bulldog Club of America
German Wirehaired Pointer Club of America
Health & Rescue Foundation of the Petit Basset Griffon Vendeen Club of America
Irish Setter Club of America Foundation, Inc.
Irish Setter Club of Milwaukee
Labrador Retriever Club, Inc.
Master National Retriever Club Foundation
Nespola Charitable Foundation
Newfoundland Club of America Charitable Trust
Rottweiler Health Foundation
Saluki Health Research, Inc.
Scottish Terrier Club of America Health Trust Fund
Soft Coated Wheaten Terrier Club of America Endowment, Inc.
Versatility in Poodles, Inc.
Vizsla Club of America Welfare Foundation
Weimaraner Foundation Fund Corporation

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Help Future Generations of Dogs

Participate in canine health research by providing samples or by enrolling in a clinical trial. Samples are needed from healthy dogs and dogs affected by specific diseases.

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Help Future Generations of Dogs

Participate in canine health research by providing samples or by enrolling in a clinical trial. Samples are needed from healthy dogs and dogs affected by specific diseases.

Learn How to Help

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