Peer-Reviewed Publications Resulting from CHF-funded Grants
We invite you to learn about publications resulting from the Foundation's investments in research. One way CHF measures success in grantmaking is through the production of peer-reviewed publications. CHF-supported research has been published in 218 different peer-reviewed journals, including Nature Genetics and Science and frequently in journals such as the Journal of Veterinary Internal Medicine, Animal Genetics and the American Journal of Veterinary Research. By consistently funding the most innovative research, the AKC Canine Health Foundation is realizing both small milestones and major breakthroughs in canine health.
You may search the complete list of peer-reviewed publications by research program area, breed and/or disease associated with the grant.
To browse publications by year you may also wish to view our Impact Report.
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Grant Number: 00896-A Research Program Area: Oncology |
Phase I Clinical Trial and Pharmacokinetics of Intravesical Mytomycin C (MMC) for the Treatment of Canine Transitional Cell Carcinoma (TC) of the Urinary Bladder Abbo, A. H., Jones, D. R., Masters, A. R., Stewart, J. C., Fourez, L., & Knapp, D. W. (2010). Phase I Clinical Trial and Pharmacokinetics of Intravesical Mitomycin C in Dogs with Localized Transitional Cell Carcinoma of the Urinary Bladder. Journal of Veterinary Internal Medicine, 24(5), 1124–1130. https://doi.org/10.1111/j.1939-1676.2010.0569.x |
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Grant Number: 1093B-T Research Program Area: Oncology |
Positional Cloning of the Gene(s) for Gastric Cancer in the Chow Chow Parker, H. G., Shearin, A. L., & Ostrander, E. A. (2010). Man’s Best Friend Becomes Biology’s Best in Show: Genome Analyses in the Domestic Dog. Annual Review of Genetics, 44(1), 309–336. https://doi.org/10.1146/annurev-genet-102808-115200
Shearin, A. L., & Ostrander, E. A. (2010). Leading the way: canine models of genomics and disease. Disease Models & Mechanisms, 3(1–2), 27–34. https://doi.org/10.1242/dmm.004358
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Grant Number: 00675-A Research Program Area: Oncology |
Evaluation of the Safety of Cisplatin/COX-2 Inhibitor Treatment for Canine Cancer Greene, S. N., Ramos-Vara, J. A., Craig, B. A., Hooser, S. B., Anderson, C., Fourez, L. M., … Knapp, D. W. (2010). Effects of cyclooxygenase inhibitor treatment on the renal toxicity of cisplatin in rats. Cancer Chemotherapy and Pharmacology, 65(3), 549–556. https://doi.org/10.1007/s00280-009-1061-2 |
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Grant Number: 00847-A Research Program Area: Epilepsy Initiative |
Mapping and Identification of the Mutation Responsible for Epilepsy in the Chinook Packer, R. A., Patterson, E. E., Taylor, J. F., Coates, J. R., Schnabel, R. D., & O’Brien, D. P. (2010). Characterization and Mode of Inheritance of a Paroxysmal Dyskinesia in Chinook Dogs: Paroxysmal Dyskinesia. Journal of Veterinary Internal Medicine, 24(6), 1305–1313. https://doi.org/10.1111/j.1939-1676.2010.0629.x |
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Grant Number: 917 Research Program Area: Epilepsy Initiative |
Genetic Determinants of Canine Epilepsy in the Border Collie and the Staffordshire Bull Terrier Short, A. D., Mellersh, C. S., Platt, H., Carter, S. D., Timofte, D., Lohi, H., & Ollier, W. E. R. (2010). Exonic mutations in the L2HGDH gene in Staffordshire Bull Terriers. Veterinary Record, 167(12), 455–457. https://doi.org/10.1136/vr.c4476
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Grant Number: 908 Research Program Area: Cardiology |
Serotonin Type 2A Receptor Antagonist Therapy for Preventing the Progression of Myxomatous Mitral Valve Disease Oyama, M. A., & Levy, R. J. (2010). Insights into Serotonin Signaling Mechanisms Associated with Canine Degenerative Mitral Valve Disease. Journal of Veterinary Internal Medicine, 24(1), 27–36. https://doi.org/10.1111/j.1939-1676.2009.0411.x |
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Grant Number: 00883-A Research Program Area: Immunology and Infectious Disease |
Training and Racing Associated Hypoglobulinemia in Elite Alaskan Sled Dogs McKenzie, E., Lupfer, C., Banse, H., Hinchcliff, K., Love, S., Nelson, Jr, S., … Pastey, M. (2010). Hypogammaglobulinemia in Racing Alaskan Sled Dogs. Journal of Veterinary Internal Medicine, 24(1), 179–184. https://doi.org/10.1111/j.1939-1676.2009.0416.x |
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Grant Number: 00935A Research Program Area: Oncology |
Positional Cloning of Two Genes for Malignant Histiocytosis (MH) in the Bernese Mountain Dog Abadie, J., Hedan, B., Cadieu, E., De Brito, C., Devauchelle, P., Bourgain, C., … Andre, C. (2009). Epidemiology, Pathology, and Genetics of Histiocytic Sarcoma in the Bernese Mountain Dog Breed. Journal of Heredity, 100(Supplement 1), S19–S27. https://doi.org/10.1093/jhered/esp039
Shearin, A. L., & Ostrander, E. A. (2010). Leading the way: canine models of genomics and disease. Disease Models & Mechanisms, 3(1–2), 27–34. https://doi.org/10.1242/dmm.004358
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Grant Number: 759 Research Program Area: Immunology and Infectious Disease |
Investigation of Antigenic Causes of Vaccine-Associated Allergic Reactions in Dogs Moore, G. E., & HogenEsch, H. (2010). Adverse Vaccinal Events in Dogs and Cats. Veterinary Clinics of North America: Small Animal Practice, 40, 393–407. https://doi.org/10.1016/j.cvsm.2010.02.002 |
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Grant Number: 00799-A Research Program Area: Immunology and Infectious Disease |
Development of Sensitive and Specific Diagnostic Tests to Aid in Eradication of Leishmania infantum from North American Foxhounds
Boggiatto, P. M., Ramer-Tait, A. E., Metz, K., Kramer, E. E., Gibson-Corley, K., Mullin, K., … Petersen, C. A. (2010). Immunologic Indicators of Clinical Progression during Canine Leishmania infantum Infection. Clinical and Vaccine Immunology, 17(2), 267–273. https://doi.org/10.1128/CVI.00456-09 Gibson-Corley, K. N., Hostetter, J. M., Hostetter, S. J., Mullin, K., Ramer-Tait, A. E., Boggiatto, P. M., & Petersen, C. A. (2008). Disseminated Leishmania infantum infection in two sibling foxhounds due to possible vertical transmission. The Canadian Veterinary Journal = La Revue Veterinaire Canadienne, 49(10), 1005–1008. |
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Grant Number: 747 Research Program Area: Ophthalmology |
The Mapping and Characterization of Mutations Responsible for Canine Glaucoma Farias, F. H. G., Johnson, G. S., Taylor, J. F., Giuliano, E., Katz, M. L., Sanders, D. N., … Mellersh, C. (2010). An ADAMTS17 Splice Donor Site Mutation in Dogs with Primary Lens Luxation. Investigative Ophthalmology & Visual Science, 51(9), 4716–4721. https://doi.org/10.1167/iovs.09-5142
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Grant Number: 778 Research Program Area: Oncology - Osteosarcoma |
Role of Regulatory T Cells in Dogs with Osteosarcoma Biller, B. J., Guth, A., Burton, J. H., & Dow, S. W. (2010). Decreased Ratio of CD8+ T Cells to Regulatory T Cells Associated with Decreased Survival in Dogs with Osteosarcoma. Journal of Veterinary Internal Medicine, 24(5), 1118–1123. https://doi.org/10.1111/j.1939-1676.2010.0557.x
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Grant Number: 662 Research Program Area: General Canine Health |
A Canine Linkage Map with More Than 2000 New Markers Mined from the Genome Sequence Greer, K. A., Wong, A. K., Liu, H., Famula, T. R., Pedersen, N. C., Ruhe, A., … Neff, M. W. (2010). Necrotizing meningoencephalitis of Pug Dogs associates with dog leukocyte antigen class II and resembles acute variant forms of multiple sclerosis. Tissue Antigens. https://doi.org/10.1111/j.1399-0039.2010.01484.x
Wong, A. K., & Neff, M. W. (2009). DOGSET?: pre-designed primer sets for fine-scale mapping and DNA sequence interrogation in the dog. Animal Genetics, 40(4), 569–571. https://doi.org/10.1111/j.1365-2052.2009.01875.x
Wong, A. K., Ruhe, A. L., Dumont, B. L., Robertson, K. R., Guerrero, G., Shull, S. M., … Neff, M. W. (2010). A Comprehensive Linkage Map of the Dog Genome. Genetics, 184(2), 595–605. https://doi.org/10.1534/genetics.109.106831 |
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Grant Number: 00881-A Research Program Area: Ophthalmology |
Identifying the Mutation Causing Lens Luxation in the Tibetan Terrier Farias, F. H. G., Johnson, G. S., Taylor, J. F., Giuliano, E., Katz, M. L., Sanders, D. N., … Mellersh, C. (2010). An ADAMTS17 Splice Donor Site Mutation in Dogs with Primary Lens Luxation. Investigative Ophthalmology & Visual Science, 51(9), 4716–4721. https://doi.org/10.1167/iovs.09-5142 |
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Grant Number: 01062-A Research Program Area: Musculoskeletal Conditions and Disease |
Knee Kinematics, Kinetics and Neuromuscular Patterns in Labrador Retrievers Predisposed to Cranial Cruciate Disease Griffon, D. J. (2010). A Review of the Pathogenesis of Canine Cranial Cruciate Ligament Disease as a Basis for Future Preventive Strategies. Veterinary Surgery, 39(4), 399–409. https://doi.org/10.1111/j.1532-950X.2010.00654.x
Mostafa, A. A., Griffon, D. J., Thomas, M. W., & Constable, P. D. (2010). Morphometric Characteristics of the Pelvic Limb Musculature of Labrador Retrievers with and without Cranial Cruciate Ligament Deficiency. Veterinary Surgery, 39(3), 380–389. https://doi.org/10.1111/j.1532-950X.2010.00657.x
Ragetly, C. A., Griffon, D. J., Mostafa, A. A., Thomas, J. E., & Hsiao-Wecksler, E. T. (2010). Inverse Dynamics Analysis of the Pelvic Limbs in Labrador Retrievers With and Without Cranial Cruciate Ligament Disease. Veterinary Surgery, 39(4), 513–522. https://doi.org/10.1111/j.1532-950X.2010.00680.x
Unis, M. D., Johnson, A. L., Griffon, D. J., Schaeffer, D. J., Ragetly, G. R., Hoffer, M. J., & Ragetly, C. A. (2010). Evaluation of Intra- and Interobserver Variability and Repeatability of Tibial Plateau Angle Measurements with Digital Radiography Using a Novel Digital Radiographic Program. Veterinary Surgery, 39(2), 187–194. https://doi.org/10.1111/j.1532-950X.2009.00641.x |
Help Future Generations of Dogs
Participate in canine health research by providing samples or by enrolling in a clinical trial. Samples are needed from healthy dogs and dogs affected by specific diseases.
Help Future Generations of Dogs
Participate in canine health research by providing samples or by enrolling in a clinical trial. Samples are needed from healthy dogs and dogs affected by specific diseases.
