Peer-Reviewed Publications Resulting from CHF-funded Grants
We invite you to learn about publications resulting from the Foundation's investments in research. One way CHF measures success in grantmaking is through the production of peer-reviewed publications. CHF-supported research has been published in 218 different peer-reviewed journals, including Nature Genetics and Science and frequently in journals such as the Journal of Veterinary Internal Medicine, Animal Genetics and the American Journal of Veterinary Research. By consistently funding the most innovative research, the AKC Canine Health Foundation is realizing both small milestones and major breakthroughs in canine health.
You may search the complete list of peer-reviewed publications by research program area, breed and/or disease associated with the grant.
To browse publications by year you may also wish to view our Impact Report.
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Grant Number: 02231-A Research Program Area: General Canine Health |
Bioavailability of Suppository Acetaminophen for Treatment of Pain in Healthy and Critically Ill Dogs Sikina, E. R., Bach, J. F., Lin, Z., Gehring, R., & KuKanich, B. (2018). Bioavailability of suppository acetaminophen in healthy and hospitalized ill dogs. Journal of Veterinary Pharmacology and Therapeutics, 41(5), 652–658. https://doi.org/10.1111/jvp.12664 |
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Grant Number: 02215 Research Program Area: Oncology, Oncology - Osteosarcoma |
A Cancer Vaccine for Canine Osteosarcoma Sahay, B., Hutchison, S., Cascio, M., Lejeune, A., Souza, C., Szivek, A., … Milner, R. J. (2018). Abstract A07: Changes in immune profiles of osteosarcoma dogs receiving a GD3-based vaccine concurrently with carboplatin chemotherapy and surgery. In Cancer Immunology Research (Vol. 6, pp. A07–A07). https://doi.org/10.1158/2326-6074.TUMIMM17-A07
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Grant Number: 01898-A Research Program Area: Cardiology |
Enhancing Diagnosis and Treatment of Cardiomyopathy through Identification of Biological Markers of Disease Cunningham, S. M., Aona, B. D., Antoon, K., Rush, J. E., & Barton, B. A. (2018). Echocardiographic assessment of right ventricular systolic function in Boxers with arrhythmogenic right ventricular cardiomyopathy. Journal of Veterinary Cardiology, 20(5), 343–353. https://doi.org/10.1016/j.jvc.2018.07.005 |
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Grant Number: 1602 Research Program Area: Endocrinology |
Defining the Cause of Hyperadrenocorticism Zimmerman, K. L., Panciera, D. L., Hoeschele, I., Monroe, W. E., Todd, S. M., Werre, S. R., … Lake, B. B. (2018). Adrenocortical Challenge Response and Genomic Analyses in Scottish Terriers with Increased Alkaline Phosphate Activity. Frontiers in Veterinary Science, 5. https://doi.org/10.3389/fvets.2018.00231 |
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Grant Number: 01762 Research Program Area: Musculoskeletal Conditions and Disease |
Use of Plasma-Derived Growth Factors to Heal Cruciate Rupture Fazio, C. G., Muir, P., Schaefer, S. L., & Waller, K. R. (2017). Accuracy of 3 Tesla magnetic resonance imaging using detection of fiber loss and a visual analog scale for diagnosing partial and complete cranial cruciate ligament ruptures in dogs. Veterinary Radiology & Ultrasound, 59(1), 64–78. https://doi.org/10.1111/vru.12567 Racette, M., Al saleh, H., Waller, K. R., Bleedorn, J. A., McCabe, R. P., Vanderby, R., … Muir, P. (2016). 3D FSE Cube and VIPR-aTR 3.0 Tesla magnetic resonance imaging predicts canine cranial cruciate ligament structural properties. The Veterinary Journal, 209, 150–155. https://doi.org/10.1016/j.tvjl.2015.10.055 Sample, S. J., Racette, M. A., Hans, E. C., Volstad, N. J., Holzman, G., Bleedorn, J. A., … Muir, P. (2017). Radiographic and magnetic resonance imaging predicts severity of cruciate ligament fiber damage and synovitis in dogs with cranial cruciate ligament rupture. PLOS ONE, 12(6), e0178086. https://doi.org/10.1371/journal.pone.0178086 Sample, S. J., Racette, M. A., Hans, E. C., Volstad, N. J., Schaefer, S. L., Bleedorn, J. A., … Muir, P. (2018). Use of a platelet-rich plasma-collagen scaffold as a bioenhanced repair treatment for management of partial cruciate ligament rupture in dogs. PLOS ONE, 13(6), e0197204. https://doi.org/10.1371/journal.pone.0197204 |
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Grant Number: 00898-A Research Program Area: Cardiology |
Diagnosis and Progression of Acquired Mitral Valve Disease in Whippets Stepien, R. L., Kellihan, H. B., & Luis Fuentes, V. (2017). Prevalence and diagnostic characteristics of non-clinical mitral regurgitation murmurs in North American Whippets. Journal of Veterinary Cardiology, 19(4), 317–324. https://doi.org/10.1016/j.jvc.2017.04.004 |
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Grant Number: 02142-A Research Program Area: Musculoskeletal Conditions and Disease |
Development of Magnetic Resonance Imaging as a Non-Invasive Tool to Accurately Evaluate Elbow Dysplasia Franklin, S. P., Burke, E. E., & Holmes, S. P. (2017). Utility of MRI for Characterizing Articular Cartilage Pathology in Dogs with Medial Coronoid Process Disease. Frontiers in Veterinary Science, 4. https://doi.org/10.3389/fvets.2017.00025 |
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Grant Number: 02118-A Research Program Area: Reproductive Conditions |
Targeting the Mechanism of Bacterial Adherence during Pyometra to Develop an Effective, Non-Invasive Treatment for Disease Gabriel, C., Becher-Deichsel, A., Hlavaty, J., Mair, G., & Walter, I. (2016). The physiological expression of scavenger receptor SR-B1 in canine endometrial and placental epithelial cells and its potential involvement in pathogenesis of pyometra. Theriogenology, 85(9), 1599-1609.e2. https://doi.org/10.1016/j.theriogenology.2016.01.021 Mair, G., Unger, H., & Gabriel, C. (2017). Combining RPL27 with OAZ1 or RPL8 as Universal Normalizers of Gene Expression in Canine Endometrial Studies. International Journal of Veterinary Science and Technology, 1(1), 23–24. |
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Grant Number: 1731 Research Program Area: Neurology |
A Novel Approach to Understanding How Meningoencephalomyelitis Develops In Dogs Jeffery, N. D., Barker, A. K., Alcott, C. J., Levine, J. M., Meren, I., Wengert, J., … Suchodolski, J. S. (2017). The Association of Specific Constituents of the Fecal Microbiota with Immune-Mediated Brain Disease in Dogs. PLOS ONE, 12(1), e0170589. https://doi.org/10.1371/journal.pone.0170589 |
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Grant Number: 02123-A Research Program Area: Reproductive Conditions |
Identifying the Gene Responsible For Inherited Infertility and Sterility in 28 Breeds Meyers-Wallen, V. N., Boyko, A. R., Danko, C. G., Grenier, J. K., Mezey, J. G., Hayward, J. J., … Sinclair, A. H. (2017). XX Disorder of Sex Development is associated with an insertion on chromosome 9 and downregulation of RSPO1 in dogs (Canis lupus familiaris). PLOS ONE, 12(10), e0186331. https://doi.org/10.1371/journal.pone.0186331 |
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Grant Number: 01995 Research Program Area: Behavior |
Understanding the Flexibility and Limitations of How Dogs Acquire Knowledge and Understanding: Application to Service Dog Emotional Health and Selection Bray, E. E., MacLean, E. L., & Hare, B. A. (2015). Increasing arousal enhances inhibitory control in calm but not excitable dogs. Animal Cognition, 18(6), 1317–1329. https://doi.org/10.1007/s10071-015-0901-1 MacLean, E. L., & Hare, B. (2018). Enhanced Selection of Assistance and Explosive Detection Dogs Using Cognitive Measures. Frontiers in Veterinary Science, 5. https://doi.org/10.3389/fvets.2018.00236 MacLean, E. L., Herrmann, E., Suchindran, S., & Hare, B. (2017). Individual differences in cooperative communicative skills are more similar between dogs and humans than chimpanzees. Animal Behaviour, 126, 41–51. https://doi.org/10.1016/j.anbehav.2017.01.005 |
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Grant Number: 02148-A Research Program Area: Blood Disorders |
The Prevalence of the Dal-Negative Blood Type and Its Mode of Inheritance in Doberman Pinschers and in Dalmatians Goulet, S., Giger, U., Arsenault, J., Abrams-Ogg, A., Euler, C. C., & Blais, M.-C. (2017). Prevalence and Mode of Inheritance of the Dal Blood Group in Dogs in North America. Journal of Veterinary Internal Medicine, 31(3), 751–758. https://doi.org/10.1111/jvim.14693 |
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Grant Number: 02124-A Research Program Area: Reproductive Conditions |
Determining the Characteristics of Sperm That Accurately Predict Fertility of Stud Dogs Hesser, A., Darr, C., Gonzales, K., Power, H., Scanlan, T., Thompson, J., … Meyers, S. (2017). Semen evaluation and fertility assessment in a purebred dog breeding facility. Theriogenology, 87, 115–123. https://doi.org/10.1016/j.theriogenology.2016.08.012 |
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Grant Number: 01893-A Research Program Area: Musculoskeletal Conditions and Disease |
A Novel, Practical, and Cost-Effective Treatment for Canine Arthritis Sherwood, J. M., Roush, J. K., Armbrust, L. J., & Renberg, W. C. (2017). Prospective Evaluation of Intra-Articular Dextrose Prolotherapy for Treatment of Osteoarthritis in Dogs. Journal of the American Animal Hospital Association, 53(3), 135–142. https://doi.org/10.5326/JAAHA-MS-6508 |
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Grant Number: 927 Research Program Area: Neurology |
Gene Discovery in Hereditary Cerebellar Abiotrophy of Scottish Terriers Urkasemsin, G., Linder, K. E., Bell, J. S., De Lahunta, A., & Olby, N. J. (2010). Hereditary Cerebellar Degeneration in Scottish Terriers. Journal of Veterinary Internal Medicine, 24(3), 565–570. https://doi.org/10.1111/j.1939-1676.2010.0499.x
Urkasemsin, G., Linder, K. E., Bell, J. S., de Lahunta, A., & Olby, N. J. (2012). Mapping of Purkinje Neuron Loss and Polyglucosan Body Accumulation in Hereditary Cerebellar Degeneration in Scottish Terriers. Veterinary Pathology, 49(5), 852–859. https://doi.org/10.1177/0300985811412622
Urkasemsin, G., Nielsen, D. M., Singleton, A., Arepalli, S., Hernandez, D., Agler, C., & Olby, N. J. (2017). Genetics of Hereditary Ataxia in Scottish Terriers. Journal of Veterinary Internal Medicine, 31(4), 1132–1139. https://doi.org/10.1111/jvim.14738 |
Help Future Generations of Dogs
Participate in canine health research by providing samples or by enrolling in a clinical trial. Samples are needed from healthy dogs and dogs affected by specific diseases.
Help Future Generations of Dogs
Participate in canine health research by providing samples or by enrolling in a clinical trial. Samples are needed from healthy dogs and dogs affected by specific diseases.
