Peer-Reviewed Publications Resulting from CHF-funded Grants

We invite you to learn about publications resulting from the Foundation's investments in research. One way CHF measures success in grantmaking is through the production of peer-reviewed publications. CHF-supported research has been published in 218 different peer-reviewed journals, including Nature Genetics and Science and frequently in journals such as the Journal of Veterinary Internal Medicine, Animal Genetics and the American Journal of Veterinary Research.  By consistently funding the most innovative research, the AKC Canine Health Foundation is realizing both small milestones and major breakthroughs in canine health.

You may search the complete list of peer-reviewed publications by research program area, breed and/or disease associated with the grant.

To browse publications by year you may also wish to view our Impact Report.

Research Program Area
Breed:
Disease:
 
Items 136 - 150 of 1000  Previous12345678910Next

Grant Number: 01849

Research Program Area: Cardiology

Filling the Gaps in the Canine Genome
Li, Y., Xu, J., Xiong, H., Ma, Z., Wang, Z., Kipreos, E. T., … Zhao, S. (2014). Cancer driver candidate genes AVL9, DENND5A and NUPL1 contribute to MDCK cystogenesis. Oncoscience, 1, 854. https://doi.org/10.18632/oncoscience.107

Liu, D., Xiong, H., Ellis, A. E., Northrup, N. C., Rodriguez, C. O., O’Regan, R. M., … Zhao, S. (2014). Molecular Homology and Difference between Spontaneous Canine Mammary Cancer and Human Breast Cancer. Cancer Research, 74(18), 5045–5056. https://doi.org/10.1158/0008-5472.CAN-14-0392

Liu, Deli, Xiong, H., Ellis, A. E., Northrup, N. C., Dobbin, K. K., Shin, D. M., & Zhao, S. (2015). Canine Spontaneous Head and Neck Squamous Cell Carcinomas Represent Their Human Counterparts at the Molecular Level. PLOS Genetics, 11(6), e1005277. https://doi.org/10.1371/journal.pgen.1005277

Wang, J., Wang, T., Bishop, M. A., Edwards, J. F., Yin, H., Dalton, S., … Zhao, S. (2018). Collaborating genomic, transcriptomic and microbiomic alterations lead to canine extreme intestinal polyposis. Oncotarget, 9(49). https://doi.org/10.18632/oncotarget.25646

Grant Number: 02138

Research Program Area: Endocrinology

Development of Accurate Diagnostic Tests for Canine Hypothyroidism

Pijnacker, T., Kooistra, H. S., Vermeulen, C. F., van der Vinne, M., Prins, M., Galac, S., & Mol, J. A. (2018). Use of basal and TRH-stimulated plasma growth hormone concentrations to differentiate between primary hypothyroidism and nonthyroidal illness in dogs. Journal of Veterinary Internal Medicine, 32(4), 1319–1324. https://doi.org/10.1111/jvim.15139

Grant Number: 02455-A

Research Program Area: Oncology

Identification of genetic mutations in anal sac carcinoma in English Cocker Spaniels


Wang, J., Wang, T., Sun, Y., Feng, Y., Kisseberth, W. C., Henry, C. J., … Zhao, S. (2018). Proliferative and Invasive Colorectal Tumors in Pet Dogs Provide Unique Insights into Human Colorectal Cancer. Cancers, 10(9), 330. https://doi.org/10.3390/cancers10090330



Zhang, M., Liu, D., Tang, J., Feng, Y., Wang, T., Dobbin, K. K., … Zhao, S. (2018). SEG - A Software Program for Finding Somatic Copy Number Alterations in Whole Genome Sequencing Data of Cancer. Computational and Structural Biotechnology Journal, 16, 335–341. https://doi.org/10.1016/j.csbj.2018.09.001

Grant Number: 02315-A

Research Program Area: Oncology - Lymphoma

Discovering Peptide Targets for Development of Adoptive Cell Therapy for Peripheral T-Cell Lymphoma
Nemec, P. S., Kapatos, A., Holmes, J. C., & Hess, P. R. (2018). The prevalent Boxer MHC class Ia allotype dog leukocyte antigen (DLA)-88*034:01 preferentially binds nonamer peptides with a defined motif. HLA, 92(6), 403–407. https://doi.org/10.1111/tan.13398

Grant Number: 01826

Research Program Area: Oncology

A Novel Treatment for Brain Tumors Using a One Medicine Approach

Freeman, A. C., Platt, S. R., Holmes, S., Kent, M., Robinson, K., Howerth, E., … Hadjipanayis, C. G. (2018). Convection-enhanced delivery of cetuximab conjugated iron-oxide nanoparticles for treatment of spontaneous canine intracranial gliomas. Journal of Neuro-Oncology, 137(3), 653–663. https://doi.org/10.1007/s11060-018-2764-1

Grant Number: 2011

Research Program Area: Endocrinology

Identification of Novel Drugs to Halt the Metastasis of Tumors That Cause Cushing's Syndrome
Galac, S., Kool, M. M. J., van den Berg, M. F., Mol, J. A., & Kooistra, H. S. (2014). Expression of steroidogenic factor 1 in canine cortisol-secreting adrenocortical tumors and normal adrenals. Domestic Animal Endocrinology, 49, 1–5. https://doi.org/10.1016/j.domaniend.2014.04.002
 
Galac, Sara. (2016). Cortisol-secreting adrenocortical tumours in dogs and their relevance for human medicine. Molecular and Cellular Endocrinology, 421, 34–39. https://doi.org/10.1016/j.mce.2015.06.026
 
Galac, Sara, & Wilson, D. B. (2015). Animal Models of Adrenocortical Tumorigenesis. Endocrinology and Metabolism Clinics of North America, 44(2), 297–310. https://doi.org/10.1016/j.ecl.2015.02.003
 
Sanders, K., Mol, J. A., Kooistra, H. S., Slob, A., & Galac, S. (2016). New Insights in the Functional Zonation of the Canine Adrenal Cortex. Journal of Veterinary Internal Medicine, 30(3), 741–750. https://doi.org/10.1111/jvim.13946
 
Sanders, K., Mol, J. A., Slob, A., Kooistra, H. S., & Galac, S. (2018a). Steroidogenic factor-1 inverse agonists as a treatment option for canine hypercortisolism: In vitro study. Domestic Animal Endocrinology, 63, 23–30. https://doi.org/10.1016/j.domaniend.2017.11.001
 
Sanders, K., Mol, J. A., Slob, A., Kooistra, H. S., & Galac, S. (2018b). Steroidogenic factor-1 inverse agonists as a treatment option for canine hypercortisolism: In vitro study. Domestic Animal Endocrinology, 63, 23–30. https://doi.org/10.1016/j.domaniend.2017.11.001
 
Sanders, R. A., Kurosawa, T. A., & Sist, M. D. (2018). Ambulatory electrocardiographic evaluation of the occurrence of arrhythmias in healthy Salukis. Journal of the American Veterinary Medical Association, 252(8), 966–969. https://doi.org/10.2460/javma.252.8.966

Grant Number: 01762

Research Program Area: Musculoskeletal Conditions and Disease

Use of Plasma-Derived Growth Factors to Heal Cruciate Rupture

Fazio, C. G., Muir, P., Schaefer, S. L., & Waller, K. R. (2017). Accuracy of 3 Tesla magnetic resonance imaging using detection of fiber loss and a visual analog scale for diagnosing partial and complete cranial cruciate ligament ruptures in dogs. Veterinary Radiology & Ultrasound, 59(1), 64–78. https://doi.org/10.1111/vru.12567

Racette, M., Al saleh, H., Waller, K. R., Bleedorn, J. A., McCabe, R. P., Vanderby, R., … Muir, P. (2016). 3D FSE Cube and VIPR-aTR 3.0 Tesla magnetic resonance imaging predicts canine cranial cruciate ligament structural properties. The Veterinary Journal, 209, 150–155. https://doi.org/10.1016/j.tvjl.2015.10.055

Sample, S. J., Racette, M. A., Hans, E. C., Volstad, N. J., Holzman, G., Bleedorn, J. A., … Muir, P. (2017). Radiographic and magnetic resonance imaging predicts severity of cruciate ligament fiber damage and synovitis in dogs with cranial cruciate ligament rupture. PLOS ONE, 12(6), e0178086. https://doi.org/10.1371/journal.pone.0178086

Sample, S. J., Racette, M. A., Hans, E. C., Volstad, N. J., Schaefer, S. L., Bleedorn, J. A., … Muir, P. (2018). Use of a platelet-rich plasma-collagen scaffold as a bioenhanced repair treatment for management of partial cruciate ligament rupture in dogs. PLOS ONE, 13(6), e0197204. https://doi.org/10.1371/journal.pone.0197204

Grant Number: 01859-A

Research Program Area: Cardiology

Defining the Significance of Irregular Heartbeats through Early Monitoring
Kurosawa, T. A., Sist, M. D., & Sanders, R. A. (2018). Echocardiographic variables in healthy North American Salukis. Journal of Veterinary Cardiology, 20(5), 301–306. https://doi.org/10.1016/j.jvc.2018.07.003
 
Sanders, R. A., Kurosawa, T. A., & Sist, M. D. (2018). Ambulatory electrocardiographic evaluation of the occurrence of arrhythmias in healthy Salukis. Journal of the American Veterinary Medical Association, 252(8), 966–969. https://doi.org/10.2460/javma.252.8.966

Grant Number: 02353-A

Research Program Area: General Canine Health

Characterization of Naturally-Occurring Neuropathic Pain in Dogs
Ruel, H. L., Watanabe, R., Evangelista, M. C., Beauchamp, G., & Steagall, P. V. (2018). Feasibility and reliability of electrical, mechanical and thermal nociceptive testing and assessment of diffuse noxious inhibitory control in dogs. Journal of Pain Research, 11, 2491–2496. https://doi.org/10.2147/JPR.S164483

Grant Number: 1658

Research Program Area: Kidney & Urological Disease

Early Detection of Chronic Kidney Disease to Prevent Kidney Damage

Hokamp, J. A., Cianciolo, R. E., Boggess, M., Lees, G. E., Benali, S. L., Kovarsky, M., & Nabity, M. B. (2016). Correlation of Urine and Serum Biomarkers with Renal Damage and Survival in Dogs with Naturally Occurring Proteinuric Chronic Kidney Disease. Journal of Veterinary Internal Medicine, 30(2), 591–601. https://doi.org/10.1111/jvim.13832

Hokamp, J. A., Leidy, S. A., Gaynanova, I., Cianciolo, R. E., & Nabity, M. B. (2018). Correlation of electrophoretic urine protein banding patterns with severity of renal damage in dogs with proteinuric chronic kidney disease. Veterinary Clinical Pathology, 47(3), 425–434. https://doi.org/10.1111/vcp.12648

Grant Number: 02231-A

Research Program Area: General Canine Health

Bioavailability of Suppository Acetaminophen for Treatment of Pain in Healthy and Critically Ill Dogs

Sikina, E. R., Bach, J. F., Lin, Z., Gehring, R., & KuKanich, B. (2018). Bioavailability of suppository acetaminophen in healthy and hospitalized ill dogs. Journal of Veterinary Pharmacology and Therapeutics, 41(5), 652–658. https://doi.org/10.1111/jvp.12664

Grant Number: 01869-A

Research Program Area: Musculoskeletal Conditions and Disease

Addendum to 1584: Creation of a Conformation Score To Evaluate Susceptibility to Cranial Cruciate Ligament Disease
Cunningham, D. P., Mostafa, A. A., Gordan-Evans, W. J., Boudrieau, R. J., & Griffon, D. J. (2017). Factors contributing to the variability of a predictive score for cranial cruciate ligament deficiency in Labrador Retrievers. BMC Veterinary Research, 13(1). https://doi.org/10.1186/s12917-017-1154-9
 
Griffon, D. J., Cunningham, D., Gordon-Evans, W. J., Tanaka, R., Bruecker, K. A., & Boudrieau, R. J. (2017). Evaluation of a scoring system based on conformation factors to predict cranial cruciate ligament disease in Labrador Retrievers. Veterinary Surgery, 46(2), 206–212. https://doi.org/10.1111/vsu.12593
 
Mostafa, A. A., Cunningham, D. P., Boudrieau, R. J., Kowaleski, M. P., & Griffon, D. J. (2018). Influence of radiographic techniques on the measurement of femoral anteversion angles and a conformation score of pelvic limbs in Labrador Retrievers. Veterinary Surgery, 47(3), 421–430. https://doi.org/10.1111/vsu.12782

Grant Number: 01746-A

Research Program Area: Dermatology and Allergic Disease

Discovery of the Genetic Cause of Lethal Acrodermatitis
Bauer, A., Jagannathan, V., Högler, S., Richter, B., McEwan, N. A., Thomas, A., … Leeb, T. (2018). MKLN1 splicing defect in dogs with lethal acrodermatitis. PLOS Genetics, 14(3), e1007264. https://doi.org/10.1371/journal.pgen.1007264

Grant Number: 01584

Research Program Area: Musculoskeletal Conditions and Disease

Creation of a Conformation Score to Evaluate Susceptibility to Cranial Cruciate Ligament Disease

Cunningham, D. P., Mostafa, A. A., Gordan-Evans, W. J., Boudrieau, R. J., & Griffon, D. J. (2017). Factors contributing to the variability of a predictive score for cranial cruciate ligament deficiency in Labrador Retrievers. BMC Veterinary Research, 13(1). https://doi.org/10.1186/s12917-017-1154-9

Griffon, D. J., Cunningham, D., Gordon-Evans, W. J., Tanaka, R., Bruecker, K. A., & Boudrieau, R. J. (2017). Evaluation of a scoring system based on conformation factors to predict cranial cruciate ligament disease in Labrador Retrievers. Veterinary Surgery, 46(2), 206–212. https://doi.org/10.1111/vsu.12593

Keebaugh, A. E., Redman-Bentley, D., & Griffon, D. J. (2015). Influence of leash side and handlers on pressure mat analysis of gait characteristics in small-breed dogs. Journal of the American Veterinary Medical Association, 246(11), 1215–1221. https://doi.org/10.2460/javma.246.11.1215

Mostafa, A. A., Cunningham, D. P., Boudrieau, R. J., Kowaleski, M. P., & Griffon, D. J. (2018). Influence of radiographic techniques on the measurement of femoral anteversion angles and a conformation score of pelvic limbs in Labrador Retrievers. Veterinary Surgery, 47(3), 421–430. https://doi.org/10.1111/vsu.12782

Ragetly, C. A., Griffon, D. J., Hsu, M. K. I., Klump, L. M., & Hsiao-Wecksler, E. T. (2012). Kinetic and kinematic analysis of the right hind limb during trotting on a treadmill in Labrador Retrievers presumed predisposed or not predisposed to cranial cruciate ligament disease. American Journal of Veterinary Research, 73(8), 1171–1177. https://doi.org/10.2460/ajvr.73.8.1171

Ragetly, C. A., Griffon, D. J., Klump, L. M., & Hsiao-Wecksler, E. T. (2012). Pelvic Limb Kinetic and Kinematic Analysis in Labrador Retrievers Predisposed or at a Low Risk for Cranial Cruciate Ligament Disease: Pelvic Limbs Kinetic and Kinematic Analysis in Labrador Retrievers. Veterinary Surgery, 41(8), 973–982. https://doi.org/10.1111/j.1532-950X.2012.01042.x

Grant Number: 822

Research Program Area: Oncology

Canine Comparative Oncology and Genomics Consortium (CCOGC)
Sakthikumar, S., Elvers, I., Kim, J., Arendt, M. L., Thomas, R., Turner-Maier, J., … Lindblad-Toh, K. (2018). SETD2 is recurrently mutated in whole-exome sequenced canine osteosarcoma. Cancer Research, canres.3558.2017. https://doi.org/10.1158/0008-5472.CAN-17-3558
 
Webster, J. D., Simpson, E. R., Michalowski, A. M., Hoover, S. B., & Simpson, R. M. (2011). Quantifying Histological Features of Cancer Biospecimens for Biobanking Quality Assurance Using Automated Morphometric Pattern Recognition Image Analysis Algorithms. Journal of Biomolecular Techniques, 22(3), 11.

Items 136 - 150 of 1000  Previous12345678910Next

Help Future Generations of Dogs

Participate in canine health research by providing samples or by enrolling in a clinical trial. Samples are needed from healthy dogs and dogs affected by specific diseases.

Learn How to Help

Help Future Generations of Dogs

Participate in canine health research by providing samples or by enrolling in a clinical trial. Samples are needed from healthy dogs and dogs affected by specific diseases.

Learn How to Help

Get Canine Health News:
Please leave this field empty
American Kennel Club Canine Health Foundation, Inc

8051 Arco Corporate Dr.
Suite 300
Raleigh, NC 27617
(888)-682-9696

Tax ID# 13-3813813

  

© 2021 AKC Canine Health Foundation | Privacy Policy | Site Map

Site by Blackbaud, Inc.

Powered by Blackbaud
nonprofit software