Peer-Reviewed Publications Resulting from CHF-funded Grants
We invite you to learn about publications resulting from the Foundation's investments in research. One way CHF measures success in grantmaking is through the production of peer-reviewed publications. CHF-supported research has been published in 218 different peer-reviewed journals, including Nature Genetics and Science and frequently in journals such as the Journal of Veterinary Internal Medicine, Animal Genetics and the American Journal of Veterinary Research. By consistently funding the most innovative research, the AKC Canine Health Foundation is realizing both small milestones and major breakthroughs in canine health.
You may search the complete list of peer-reviewed publications by research program area, breed and/or disease associated with the grant.
To browse publications by year you may also wish to view our Impact Report.
|
Grant Number: 2447 Research Program Area: Endocrinology |
Genetic Determinants of Susceptibility to Hypothyroid Disease in Dogs Bianchi, M., Dahlgren, S., Massey, J., Dietschi, E., Kierczak, M., Lund-Ziener, M., … Rosengren Pielberg, G. (2015). A Multi-Breed Genome-Wide Association Analysis for Canine Hypothyroidism Identifies a Shared Major Risk Locus on CFA12. PLOS ONE, 10(8), e0134720. https://doi.org/10.1371/journal.pone.0134720
Kennedy, L. J., Barnes, A., Short, A., Brown, J. J., Seddon, J., Fleeman, L., … Ollier, W. E. R. (2007). Canine DLA diversity: 3. Disease studies. Tissue Antigens, 69, 292–296. https://doi.org/10.1111/j.1399-0039.2006.00781.x
Kennedy, L. J., Huson, H. J., Leonard, J., Angles, J. M., Fox, L. E., Wojciechowski, J. W., … Happ, G. M. (2006). Association of hypothyroid disease in Doberman Pinscher dogs with a rare major histocompatibility complex DLA class II haplotype. Tissue Antigens, 67(1), 53–56. https://doi.org/10.1111/j.1399-0039.2005.00518.x
Kennedy, L. J., Quarmby, S., Happ, G. M., Barnes, A., Ramsey, I. K., Dixon, R. M., … Ollier, W. E. R. (2006). Association of canine hypothyroidism with a common major histocompatibility complex DLA class II allele. Tissue Antigens, 68(1), 82–86. https://doi.org/10.1111/j.1399-0039.2006.00614.x
|
|
Grant Number: 00593B Research Program Area: Oncology - Hemangiosarcoma |
Mapping Genes Associated with Canine Hemangiosarcoma Tonomura, N., Elvers, I., Thomas, R., Megquier, K., Turner-Maier, J., Howald, C., … Lindblad-Toh, K. (2015). Genome-wide Association Study Identifies Shared Risk Loci Common to Two Malignancies in Golden Retrievers. PLOS Genetics, 11(2), e1004922. https://doi.org/10.1371/journal.pgen.1004922 |
|
Grant Number: 01698-A Research Program Area: Oncology |
Immunohistochemical quantification of the transcobalamin II protein and receptor in naturally occurring canine tumors. Sysel, A. M., Valli, V. E., & Bauer, J. A. (2015). Immunohistochemical quantification of the cobalamin transport protein, cell surface receptor and Ki-67 in naturally occurring canine and feline malignant tumors and in adjacent normal tissues. Oncotarget, 6(4), 2331–2348. https://doi.org/10.18632/oncotarget.3206 |
|
Grant Number: 00294-A Research Program Area: Musculoskeletal Conditions and Disease |
Enhancement of Current Background Information and DNA Material Necessary for the Future Development of a Molecular Genetics Study in Collies and Shetland Sheepdogs with Dermatomyositis Clark, L. A., Credille, K. M., Murphy, K. E., & Rees, C. A. (2005). Linkage of dermatomyositis in the Shetland Sheepdog to chromosome 35. Veterinary Dermatology, 16(6), 392–394. https://doi.org/10.1111/j.1365-3164.2005.00469.x
|
|
Grant Number: 02091-A Research Program Area: Oncology |
Differentiating between Localized and Disseminated Histiocytic Sarcoma in Bernese Mountain Dogs Schoenebeck, J. J., & Ostrander, E. A. (2014). Insights into Morphology and Disease from the Dog Genome Project. Annual Review of Cell and Developmental Biology, 30(1), 535–560. https://doi.org/10.1146/annurev-cellbio-100913-012927 |
|
Grant Number: 01935-B Research Program Area: Gastrointestinal Disease |
Abnormalities in the Stomach's Ability to Contract Predisposes Large-Breed Dogs to Bloat Gazzola, K. M., & Nelson, L. L. (2014). The relationship between gastrointestinal motility and gastric dilatation-volvulus in dogs. Top Companion Anim Med, 29(3), 64-66. doi:10.1053/j.tcam.2014.09.006 |
|
Grant Number: 01701-A Research Program Area: Immunology and Infectious Disease |
Determining the Effect of Pain Medication on Immune Function: Part 1 DeClue, A. E., Yu, D.-H., Prochnow, S., Axiak-Bechtel, S., Amorim, J., Tsuruta, K., … Dodam, J. (2014). Effects of opioids on phagocytic function, oxidative burst capacity, cytokine production and apoptosis in canine leukocytes. The Veterinary Journal, 200(2), 270–275. https://doi.org/10.1016/j.tvjl.2014.02.019 |
|
Grant Number: 01352-A Research Program Area: Immunology and Infectious Disease |
Detection of Brucella canis DNA in canine urine, semen and vaginal cells via qPCR Analysis Kauffman, L. K., Bjork, J. K., Gallup, J. M., Boggiatto, P. M., Bellaire, B. H., & Petersen, C. A. (2014). Early detection of Brucella canis via quantitative polymerase chain reaction analysis. Zoonoses and Public Health, 61(1), 48–54. https://doi.org/10.1111/zph.12041 |
|
Grant Number: 323 Research Program Area: Neurology |
Mapping the Gene Responsible for Hypomyelination in Weimaraner Dogs Pemberton, T. J., Choi, S., Mayer, J. A., Li, F.-Y., Gokey, N., Svaren, J., … Duncan, I. D. (2014). A mutation in the canine gene encoding folliculin-interacting protein 2 (FNIP2) associated with a unique disruption in spinal cord myelination: A Mutation in FNIP2 Disrupts Myelination. Glia, 62(1), 39–51. https://doi.org/10.1002/glia.22582 |
|
Grant Number: 01569 Research Program Area: Oncology - Lymphoma |
Evaluation of a Novel Drug to Treat Canine Cutaneous Lymphoma Morges, M. A., Burton, J. H., Saba, C. F., Vail, D. M., Burgess, K. E., & Thamm, D. H. (2014). Phase II Evaluation of VDC-1101 in Canine Cutaneous T-Cell Lymphoma. Journal of Veterinary Internal Medicine, 28(5), 1569–1574. https://doi.org/10.1111/jvim.12429
|
|
Grant Number: 925 Research Program Area: Neurology |
Identification of Mutations Causing Hereditary Cerebellar Cortical Degeneration in American Staffordshire Terriers and Old English Sheepdogs Abitbol, M., Thibaud, J.-L., Olby, N. J., Hitte, C., Puech, J.-P., Maurer, M., … Tiret, L. (2010). A canine Arylsulfatase G (ARSG) mutation leading to a sulfatase deficiency is associated with neuronal ceroid lipofuscinosis. Proceedings of the National Academy of Sciences, 107(33), 14775–14780. https://doi.org/10.1073/pnas.0914206107
Agler, C., Nielsen, D. M., Urkasemsin, G., Singleton, A., Tonomura, N., Sigurdsson, S., … Olby, N. J. (2014). Canine Hereditary Ataxia in Old English Sheepdogs and Gordon Setters Is Associated with a Defect in the Autophagy Gene Encoding RAB24. PLoS Genetics, 10(2), e1003991. https://doi.org/10.1371/journal.pgen.1003991 |
|
Grant Number: 01248 Research Program Area: Reproductive Conditions |
Whole Genome Association Analyses for Cryptorchidism in Dogs Zhao, X., Onteru, S., Saatchi, M., Garrick, D., & Rothschild, M. (2014). A genome-wide association study for canine cryptorchidism in Siberian Huskies. Journal of Animal Breeding and Genetics, 131(3), 202–209. https://doi.org/10.1111/jbg.12064 |
|
Grant Number: 1004 Research Program Area: Neurology |
Syringomyelia in the Brussels Griffon: Magnetic Resonance Imaging Findings, Clinicopathology, and Prevalence Freeman, A. C., Platt, S. R., Kent, M., Huguet, E., Rusbridge, C., & Holmes, S. (2014). Chiari-Like Malformation and Syringomyelia in American Brussels Griffon Dogs. Journal of Veterinary Internal Medicine, 28(5), 1551–1559. https://doi.org/10.1111/jvim.12421 Knowler, S. P., McFadyen, A. K., Freeman, C., Kent, M., Platt, S. R., Kibar, Z., & Rusbridge, C. (2014). Quantitative Analysis of Chiari-Like Malformation and Syringomyelia in the Griffon Bruxellois Dog. PLoS ONE, 9(2), e88120. https://doi.org/10.1371/journal.pone.0088120 |
|
Grant Number: 920 Research Program Area: Neurology |
Genetic Basis of Polyneuropathy in Leonbergers Ekenstedt, K. J., Becker, D., Minor, K. M., Shelton, G. D., Patterson, E. E., Bley, T., … Mickelson, J. R. (2014). An ARHGEF10 Deletion Is Highly Associated with a Juvenile-Onset Inherited Polyneuropathy in Leonberger and Saint Bernard Dogs. PLoS Genetics, 10(10), e1004635. https://doi.org/10.1371/journal.pgen.1004635
Pemberton, T. J., Choi, S., Mayer, J. A., Li, F.-Y., Gokey, N., Svaren, J., … Duncan, I. D. (2014). A mutation in the canine gene encoding folliculin-interacting protein 2 (FNIP2) associated with a unique disruption in spinal cord myelination. Glia, 62(1), 39–51. https://doi.org/10.1002/glia.22582 |
|
Grant Number: 1130 Research Program Area: Oncology - Lymphoma |
Measurement of Minimal Residual Disease Using Real Time PCR in Canine Lymphoma Johnston, S. A., Thamm, D. H., & Legutki, J. B. (2014). The immunosignature of canine lymphoma: Characterization and diagnostic application. BMC Cancer, 14(1).https://doi.org/10.1186/1471-2407-14-657 Thomas, R., Borst, L., Rotroff, D., Motsinger-Reif, A., Lindblad-Toh, K., Modiano, J. F., & Breen, M. (2014). Genomic profiling reveals extensive heterogeneity in somatic DNA copy number aberrations of canine hemangiosarcoma. Chromosome Research, 22(3), 305–319. https://doi.org/10.1007/s10577-014-9406-z |
Help Future Generations of Dogs
Participate in canine health research by providing samples or by enrolling in a clinical trial. Samples are needed from healthy dogs and dogs affected by specific diseases.
Help Future Generations of Dogs
Participate in canine health research by providing samples or by enrolling in a clinical trial. Samples are needed from healthy dogs and dogs affected by specific diseases.
