Peer-Reviewed Publications Resulting from CHF-funded Grants
We invite you to learn about publications resulting from the Foundation's investments in research. One way CHF measures success in grantmaking is through the production of peer-reviewed publications. CHF-supported research has been published in 218 different peer-reviewed journals, including Nature Genetics and Science and frequently in journals such as the Journal of Veterinary Internal Medicine, Animal Genetics and the American Journal of Veterinary Research. By consistently funding the most innovative research, the AKC Canine Health Foundation is realizing both small milestones and major breakthroughs in canine health.
You may search the complete list of peer-reviewed publications by research program area, breed and/or disease associated with the grant.
To browse publications by year you may also wish to view our Impact Report.
|
Grant Number: 2025 Research Program Area: Oncology - Hemangiosarcoma |
Growth Signaling Pathways in the Pathogenesis and Treatment of Canine Cancer Akhtar, N., Padilla, M. L., Dickerson, E. B., Steinberg, H., Breent, M., Auerbach, R., & Helfand, S. C. (2004). Interleukin-12 Inhibits Tumor Growth in a Novel Angiogenesis Canine Hemangiosarcoma Xenograft Model. Neoplasia, 6(2), 106–116. https://doi.org/10.1593/neo.03334 Dickerson, E. B., Thomas, R., Fosmire, S. P., Lamerato-Kozicki, A. R., Bianco, S. R., Wojcieszyn, J. W., … Modiano, J. F. (2005). Mutations of Phosphatase and Tensin Homolog Deleted from Chromosome 10 in Canine Hemangiosarcoma. Veterinary Pathology, 42(5), 618–632. https://doi.org/10.1354/vp.42-5-618 Lin, P.-Y., Fosmire, S. P., Park, S.-H., Park, J.-Y., Baksh, S., Modiano, J. F., & Weiss, R. H. (2007). Attenuation of PTEN increases p21 stability and cytosolic localization in kidney cancer cells: a potential mechanism of apoptosis resistance. Molecular Cancer, 14. |
|
Grant Number: 1870 Research Program Area: General Canine Health |
Genetics of Hereditary Deafness in the Domestic Dog
Cargill, E. J. (2004). Heritability and Segregation Analysis of Deafness in U.S. Dalmatians. Genetics, 166(3), 1385–1393. https://doi.org/10.1534/genetics.166.3.1385 Cargill, Edward J, Famula, T. R., Schnabel, R. D., Strain, G. M., & Murphy, K. E. (2005). The color of a Dalmatian’s spots: Linkage evidence to support the TYRP1 gene. BMC Veterinary Research, 1(1), 3. Cargill, E.J., Schnabel, R. D., & Murphy, K. E. (2004). Assignment of Canine MSS1 Microsatellite Markers to Chromosomes by Linkage Data. DNA Sequence, 15(3), 209–212. https://doi.org/10.1080/10425170410001704490 Tsai, K. L., Guyon, R., & Murphy, K. E. (2003). Identification of isoforms and RH mapping of canine KIT. Cytogenetic and Genome Research, 102(1–4), 261–263. https://doi.org/10.1159/000075759 |
|
Grant Number: 1629 Research Program Area: Immunology and Infectious Disease |
The Genetics of the Major Histocompatibility Complex in Canine Immune-Mediated Diseases Angles, J. M., Famula, T. R., & Pedersen, N. C. (2005). Uveodermatologic (VKH-like) syndrome in American Akita dogs is associated with an increased frequency of DQA1*00201. Tissue Antigens, 66(6), 656–665. https://doi.org/10.1111/j.1399-0039.2005.00508.x |
|
Grant Number: 2230 Research Program Area: Ophthalmology |
Continued DNA Studies in Cataracts in the Bichon Frise Gelatt, K. N., Wallace, M. R., Andrew, S. E., MacKay, E. O., & Samuelson, D. A. (2003). Cataracts in the Bichon Frise. Veterinary Ophthalmology, 6(1), 3–9. https://doi.org/10.1046/j.1463-5224.2003.00258.x
Wallace, M. R., MacKay, E. O., Gelatt, K. N., & Andrew, S. E. (2005). Inheritance of cataract in the Bichon Frise. Veterinary Ophthalmology, 8(3), 203–205. https://doi.org/10.1111/j.1463-5224.2005.00359.x |
|
Grant Number: 0002215AT Research Program Area: General Canine Health |
A BAC Map of the Canine Genome Breen, M., Hitte, C., Lorentzen, T. D., Thomas, R., Cadieu, E., Sabacan, L., … Ostrander, E. A. (2004). An integrated 4249 marker FISH/RH map of the canine genome. BMC Genomics, 5(65), 11. |
|
Grant Number: 1428 Research Program Area: Cardiology |
Inheritance Patterns and Molecular Genetic Analysis of Doberman Pinschers and Boxer Dogs with Familial Dilated Cardiomyopathy Basso, C., Fox, P. R., Meurs, K. M., Towbin, J. A., Spier, A. W., Calabrese, F., … Thiene, G. (2004). Arrhythmogenic Right Ventricular Cardiomyopathy Causing Sudden Cardiac Death in Boxer Dogs: A New Animal Model of Human Disease. Circulation, 109(9), 1180–1185. https://doi.org/10.1161/01.CIR.0000118494.07530.65
Meurs, K. M. (2004). Boxer dog cardiomyopathy: an update. Veterinary Clinics of North America: Small Animal Practice, 34(5), 1235–1244. https://doi.org/10.1016/j.cvsm.2004.05.003
Meurs, K. M., Magnon, A. L., Spier, A. W., Miller, M. W., Lehmkuhl, L. B., & Towbin, J. A. (2001). Evaluation of the cardiac actin gene in Doberman Pinschers with dilated cardiomyopathy. American Journal of Veterinary Research, 62(1), 33–36. https://doi.org/10.2460/ajvr.2001.62.33
Meurs, K. M., Miller, M. W., & Wright, N. A. (2001). Clinical features of dilated cardiomyopathy in Great Danes and results of a pedigree analysis: 17 cases (1990-2000). Journal of the American Veterinary Medical Association, 218(5), 729–732. https://doi.org/10.2460/javma.2001.218.729
Meurs, K. M., Spier, A. W., Miller, M. W., Lehmkuhl, L., & Towbin, J. A. (1999). Familial Ventricular Arrhythmias in Boxers. Journal of Veterinary Internal Medicine, 13, 437–439.
Meurs, K. M., Spier, A. W., Wright, N. A., Atkins, C. E., DeFrancesco, T. C., Gordon, S. G., … Moise, N. S. (2002). Comparison of the effects of four antiarrhythmic treatments for familial ventricular arrhythmias in Boxers. Journal of the American Veterinary Medical Association, 221(4), 522–527. https://doi.org/10.2460/javma.2002.221.522
Meurs, K. M., Spier, A. W., Wright, N. A., & Hamlin, R. L. (2001). Comparison of in-hospital versus 24-hour ambulatory electrocardiography for detection of ventricular premature complexes in mature Boxers. Journal of the American Veterinary Medical Association, 218(2), 222–224. https://doi.org/10.2460/javma.2001.218.222
|
|
Grant Number: 1252 Research Program Area: Gastrointestinal Disease |
A Prospective Study of Morphometric, Genetic & Dietary Risk Factors for Bloat in Dogs Glickman, L., Glickman, N., Schellenberg, D., Simpson, K., & Lantz, G. (1997). Multiple risk factors for the gastric dilatation-volvulus syndrome in dogs: A practitioner/owner case-control study. Journal of the American Animal Hospital Association, 33(3), 197–204. https://doi.org/10.5326/15473317-33-3-197 Glickman, L., Lantz, G., Schellenberg, D., & Glickman, N. (1998). A prospective study of survival and recurrence following the acute gastric dilatation-volvulus syndrome in 136 dogs. Journal of the American Animal Hospital Association, 34(3), 253–259. https://doi.org/10.5326/15473317-34-3-253 Glickman, L. T., Glickman, N. W., Schellenberg, D. B., Raghavan, M., & Lee, T. (2000a). Non-dietary risk factors for gastric dilatation-volvulus in large and giant breed dogs. Journal of the American Veterinary Medical Association, 217(10), 1492–1499. >https://doi.org/10.2460/javma.2000.217.1492 Glickman, L. T., Glickman, N. W., Schellenberg, D. B., Raghavan, M., & Lee, T. L. (2000b). Incidence of and breed-related risk factors for gastric dilatation-volvulus in dogs. Journal of the American Veterinary Medical Association, 216(1), 40–45. https://doi.org/10.2460/javma.2000.216.40 Raghavan, M., Glickman, N., McCabe, G., Lantz, G., & Glickman, L. T. (2004). Diet-Related Risk Factors for Gastric Dilatation-Volvulus in Dogs of High-Risk Breeds. Journal of the American Animal Hospital Association, 40(3), 192–203. https://doi.org/10.5326/0400192 Raghavan, M., Glickman, N. W., & Glickman, L. T. (2006). The Effect of Ingredients in Dry Dog Foods on the Risk of Gastric Dilatation-Volvulus in Dogs. Journal of the American Animal Hospital Association, 42(1), 28–36. https://doi.org/10.5326/0420028 Schaible, R. H., Ziech, J., Glickman, N. W., Schellenberg, D., Yi, Q., & Glickman, L. T. (1997). Predisposition to gastric dilatation-volvulus in relation to genetics of thoracic conformation in Irish Setters. Journal of the American Animal Hospital Association, 33(5), 379–383. https://doi.org/10.5326/15473317-33-5-379 Ward, M. P., Patronek, G. J., & Glickman, L. T. (2003). Benefits of prophylactic gastropexy for dogs at risk of gastric dilatation–volvulus. Preventive Veterinary Medicine, 60(4), 319–329. https://doi.org/10.1016/S0167-5877(03)00142-9 |
|
Grant Number: 2636 Research Program Area: Neurology |
Characterization of Cerebellar Cortical Degeneration in American Staffordshire Terriers Olby, N., Blot, S., Thibaud, J.-L., Phillips, J., O’Brien, D. P., Burr, J., … Breen, M. (2004). Cerebellar Cortical Degeneration in Adult American Staffordshire Terriers. Journal of Veterinary Internal Medicine, 18, 201–208. |
|
Grant Number: 0002215B Research Program Area: General Canine Health |
A BAC Map of the Canine Genome Breen, M., Hitte, C., Lorentzen, T. D., Thomas, R., Cadieu, E., Sabacan, L., … Ostrander, E. A. (2004). An integrated 4249 marker FISH/RH map of the canine genome. BMC Genomics, 5(65), 11. |
|
Grant Number: 1614 Research Program Area: Musculoskeletal Conditions and Disease |
Development of a DNA-Based Diagnostic Test for Craniomandibular Osteopathy of the Cairn Terrier, West Highland White Terrier, and Scottish Terrier Breeds Brouillette, J. A., & Venta, P. J. (2002). Within-breed heterozygosity of canine single nucleotide polymorphisms identified by across-breed comparison. Animal Genetics, 33(6), 464–467. https://doi.org/10.1046/j.1365-2052.2002.00918.x
Housley, D. J. E., Ritzert, E., & Venta, P. J. (2004). Comparative radiation hybrid map of canine chromosome 1 incorporating SNP and indel polymorphisms. Genomics, 84(2), 248–264. https://doi.org/10.1016/j.ygeno.2004.04.001 |
|
Grant Number: 0022113 Research Program Area: Musculoskeletal Conditions and Disease |
Radiographic Analysis of Tibial Plateau Angle Development in Maturing Labrador Retriever Dogs Odders, J. W., Jessen, C. R., & Lipowitz, A. J. (2004). Sequential measurements of the tibial plateau angle in large-breed, growing dogs. American Journal of Veterinary Research, 65(4), 513–518. https://doi.org/10.2460/ajvr.2004.65.513 |
|
Grant Number: 2020 Research Program Area: Kidney & Urological Disease |
Inheritance of Urinary Stone Formation in the Dalmatian Bannasch, D. L., Ling, G. V., Bea, J., & Famula, T. R. (2004). Inheritance of Urinary Calculi in the Dalmatian. Journal of Veterinary Internal Medicine, 18, 483–487.
Bannasch, D. L., Ryun, J. R., Bannasch, M. J., Schaible, R. H., Breen, M., & Ling, G. (2004). Exclusion of galectin 9 as a candidate gene for hyperuricosuria in the Dalmatian dog. Animal Genetics, 35(4), 326–328. https://doi.org/10.1111/j.1365-2052.2004.01154.x |
|
Grant Number: 2620 Research Program Area: Cardiology |
Determination of the Clinical Phenotype and Inherited Nature of Familial Subvalvular Aortic Stenosis in the Rottweiler Davainis, G. M., Meurs, K. M., & Wright, N. A. (2004). The Relationship of Resting S-T Segment Depression to the Severity of Subvalvular Aortic Stenosis and the Presence of Ventricular Premature Complexes in the Dog. Journal of the American Animal Hospital Association, 40(1), 20–23. https://doi.org/10.5326/0400020
|
|
Grant Number: 2248 Research Program Area: General Canine Health |
Generation of Canine EST Resources Palmer, L. E. (2003). A Survey of Canine Expressed Sequence Tags and a Display of Their Annotations Through a Flexible Web-Based Interface. Journal of Heredity, 94(1), 15–22. https://doi.org/10.1093/jhered/esg003 |
|
Grant Number: 0001840 Research Program Area: Immunology and Infectious Disease |
Studies of the Host (Canine) Immune Response to the Opportunistic Pathogen Malassezia pachydermatis Morris, D. O., Clayton, D. J., Drobatz, K. J., & Felsburg, P. J. (2002). Response to Malassezia pachydermatis by peripheral blood mononuclear cells from clinically normal and atopic dogs. American Journal of Veterinary Research, 63(3), 358–362. https://doi.org/10.2460/ajvr.2002.63.358 Morris, D. O., & DeBoer, D. J. (2003). Evaluation of serum obtained from atopic dogs with dermatitis attributable to Malassezia pachydermatis for passive transfer of immediate hypersensitivity to that organism. American Journal of Veterinary Research, 64(3), 262–266. https://doi.org/10.2460/ajvr.2003.64.262 |
Help Future Generations of Dogs
Participate in canine health research by providing samples or by enrolling in a clinical trial. Samples are needed from healthy dogs and dogs affected by specific diseases.
Help Future Generations of Dogs
Participate in canine health research by providing samples or by enrolling in a clinical trial. Samples are needed from healthy dogs and dogs affected by specific diseases.
