Peer-Reviewed Publications Resulting from CHF-funded Grants

We invite you to learn about publications resulting from the Foundation's investments in research. One way CHF measures success in grantmaking is through the production of peer-reviewed publications. CHF-supported research has been published in 218 different peer-reviewed journals, including Nature Genetics and Science and frequently in journals such as the Journal of Veterinary Internal Medicine, Animal Genetics and the American Journal of Veterinary Research.  By consistently funding the most innovative research, the AKC Canine Health Foundation is realizing both small milestones and major breakthroughs in canine health.

You may search the complete list of peer-reviewed publications by research program area, breed and/or disease associated with the grant.

To browse publications by year you may also wish to view our Impact Report.

Research Program Area
Breed:
Disease:
 
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Grant Number: 2042

Research Program Area: General Canine Health

Identification and Mapping of Genes Expressed in the Canine Brain
Roberts, M. C., Hitte, C., Hendrickson, J. A., Hoffmann, D. E., Flickinger, G. H., Rutherford, M. S., … Mickelson, J. R. (2003). Characterization and radiation hybrid mapping of expressed sequence tags from the canine brain. Mammalian Genome, 14(3), 203–213. https://doi.org/10.1007/s00335-002-2207-2

Grant Number: 2429

Research Program Area: Cardiology

The Assessment of Ejection Murmurs in the Boxer Dog
Koplitz, S. L., Meurs, K. M., Spier, A. W., Bonagura, J. D., Fuentes, V. L., & Wright, N. A. (2003). Aortic ejection velocity in healthy Boxers with soft cardiac murmurs and Boxers without cardiac murmurs: 201 cases (1997–2001). Journal of the American Veterinary Medical Association, 222(6), 770–774. https://doi.org/10.2460/javma.2003.222.770

Grant Number: 0001657T

Research Program Area: Endocrinology

Identification and Inheritance of DNA Markers for Addison's Disease
Famula, T. R., Belanger, J. M., & Oberbauer, A. M. (2003). Heritability and complex segregation analysis of hypoadrenocorticism in the Standard Poodle. Journal of Small Animal Practice, 44(1), 8–12. https://doi.org/10.1111/j.1748-5827.2003.tb00096.x
 
Oberbauer, A. M., Benemann, K. S., Belanger, J. M., Wagner, D. R., Ward, J. H., & Famula, T. R. (2002). Inheritance of hypoadrenocorticism in Bearded Collies. American Journal of Veterinary Research, 63(5), 643–647. https://doi.org/10.2460/ajvr.2002.63.643

Grant Number: 0001626T

Research Program Area: Oncology

Significance of Tumor Suppressor Genes in Canine Cancer
Bianco, S. R., Sun, J., Fosmire, S. P., Hance, K., Padilla, M. L., Ritt, M. G., … Modiano, J. F. (2003). Enhancing antimelanoma immune responses through apoptosis. Cancer Gene Therapy, 10(9), 726–736. https://doi.org/10.1038/sj.cgt.7700625
 
Koenig, A., Bianco, S. R., Fosmire, S., Wojcieszyn, J., & Modiano, J. F. (2002). Expression and Significance of p53, Rb, p21/waf-1, p16/ink-4a, and PTEN Tumor Suppressors in Canine Melanoma. Veterinary Pathology, 39(4), 458–472. https://doi.org/10.1354/vp.39-4-458
 
Koenig, A., Wojcieszyn, J., Weeks, B. R., & Modiano, J. F. (2001). Expression of S100a, Vimentin, NSE, and Melan A/MART-1 in Seven Canine Melanoma Cell Lines and Twenty-nine Retrospective Cases of Canine Melanoma. Veterinary Pathology, 38(4), 427–435. https://doi.org/10.1354/vp.38-4-427

Grant Number: 1634

Research Program Area: General Canine Health

Establishment of Genome-Screening Canine Microsatellite Panels for Disease Association Studies
Irion, D. N. (2003). Analysis of Genetic Variation in 28 Dog Breed Populations With 100 Microsatellite Markers. Journal of Heredity, 94(1), 81–87. https://doi.org/10.1093/jhered/esg004

Grant Number: 1607

Research Program Area: Ophthalmology

Hereditary and DNA Studies in Cataracts in the Bichon Frise
Gelatt, K. N., Wallace, M. R., Andrew, S. E., MacKay, E. O., & Samuelson, D. A. (2003). Cataracts in the Bichon Frise. Veterinary Ophthalmology, 6(1), 3–9. https://doi.org/10.1046/j.1463-5224.2003.00258.x
 
Wallace, M. R., MacKay, E. O., Gelatt, K. N., & Andrew, S. E. (2005). Inheritance of cataract in the Bichon Frise. Veterinary Ophthalmology, 8(3), 203–205. https://doi.org/10.1111/j.1463-5224.2005.00359.x

Grant Number: 1844

Research Program Area: Hepatic Disease

Determination of Genetic Relationships Among Yorkshire Terriers With Single Congenital Portosystemic Shunts
Tobias, K. M. (2003). Determination of Inheritance of Single Congenital Portosystemic Shunts in Yorkshire Terriers. Journal of the American Animal Hospital Association, 39(4), 385–389. https://doi.org/10.5326/0390385

Grant Number: 2012

Research Program Area: General Canine Health

Development of PCR Multiplexed Canine Marker Panels for the Purposes of Genome Screening and Linkage Analysis

Eggleston, M. L., Irion, D. N., Schaffer, A. L., Hughes, S. S., Draper, J. E., Robertson, K. R., … Pedersen, N. C. (2002). PCR multiplexed microsatellite panels to expedite canine genetic disease linkage analysis. Animal Biotechnology, 13(2), 223–235. https://doi.org/10.1081/ABIO-120016191

Grant Number: 1268

Research Program Area: General Canine Health

A Genetic Map of the Canine Genome
Richman, M., Mellersh, C. S., André, C., Galibert, F., & Ostrander, E. A. (2001). Characterization of a minimal screening set of 172 microsatellite markers for genome-wide screens of the canine genome. Journal of Biochemical and Biophysical Methods, 47(1–2), 137–149. https://doi.org/10.1016/S0165-022X(00)00160-3
 
Sidjanin, D. J., Zangerl, B., Johnson, J. L., Xue, F., Mellersh, C., Ostrander, E. A., … Aguirre, G. D. (2002). Cloning of the canine delta tubulin cDNA (TUBD) and mapping to CFA9. Animal Genetics, 33(2), 161–162. https://doi.org/10.1046/j.1365-2052.2002.0831d.x

Grant Number: 1633

Research Program Area: Gastrointestinal Disease

Identification of a Genetic Marker for Pancreatic Acinar Atrophy Causing Exocrine Pancreatic Insufficiency in the German Shepherd Dog
Moeller, E. M., Steiner, J. M., Clark, L. A., Murphy, K. E., Famula, T. R., Williams, D. A., … Vose, A. S. (2002). Inheritance of pancreatic acinar atrophy in German Shepherd Dogs. American Journal of Veterinary Research, 63(10), 1429–1434. https://doi.org/10.2460/ajvr.2002.63.1429

Grant Number: 01415

Research Program Area: Dermatology and Allergic Disease

Development of Anti-IgE Peptide for Treatment of Canine Allergy
Hammerberg, B., Olivry, T., & Orton, S. M. (2001). Skin mast cell histamine release following stem cell factor and high-affinity immunoglobulin E receptor cross-linking in dogs with atopic dermatitis. Veterinary Dermatology, 12(6), 339–346. https://doi.org/10.1046/j.0959-4493.2001.00273.x

Grant Number: 0002038T

Research Program Area: Oncology - Lymphoma

The Molecular Cytogenetics of Canine Lymphosarcoma: Correlating Chromosomal Changes with Clinical Disease
Thomas, R., Smith, K. C., Gould, R., Gower, S. M., Binns, M. M., & Breen, M. (2001). Molecular cytogenetic analysis of a novel high-grade canine T-lymphoblastic lymphoma demonstrating co-expression of CD3 and CD79a cell markers. Chromosome Research, 9, 649–657. https://doi.org/10.1023/A:1012904307579

Grant Number: 1815

Research Program Area: General Canine Health

Hair Coat Differences in Canine Breeds Recognized by the American Kennel Club
Credille, K. M., Venta, P. J., Breen, M., Lowe, J. K., Murphy, K. E., Ostrander, E. A., … Dunstan, R. W. (2001). DNA sequence and physical mapping of the canine transglutaminase 1 gene. Cytogenetic and Genome Research, 93(1–2), 73–76. https://doi.org/10.1159/000056952

Grant Number: 1415

Research Program Area: Dermatology and Allergic Disease

Traits of Cutaneous Mast Cell Phenotype and Function Associated with Predisposition to Canine Atopic Dermatitis
Hammerberg, B., Olivry, T., & Orton, S. M. (2001). Skin mast cell histamine release following stem cell factor and high-affinity immunoglobulin E receptor cross-linking in dogs with atopic dermatitis. Veterinary Dermatology, 12(6), 339–346. https://doi.org/10.1046/j.0959-4493.2001.00273.x

Grant Number: 2009

Research Program Area: Cardiology

Determination of the Clinical Phenotype and Inherited Nature of Dilated Cardiomyopathy in the Great Dane
Meurs, K. M., Miller, M. W., & Wright, N. A. (2001). Clinical features of dilated cardiomyopathy in Great Danes and results of a pedigree analysis: 17 cases (1990-2000). Journal of the American Veterinary Medical Association, 218(5), 729–732. https://doi.org/10.2460/javma.2001.218.729

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