1634: Establishment of Genome-Screening Canine Microsatellite Panels for Disease Association Studies

Grant Status: Closed

Grant Amount: $64,084
Niels C Pedersen, PhD; University of California, Davis
October 26, 1998 - October 25, 1999

Sponsor(s):

Breed(s): -All Dogs
Research Program Area: General Canine Health
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Project Summary

Researchers in this study grouped genetic markers into panels that contain approximately 10 markers that can be screened at the same time, saving time and money for researchers doing linkage analyses for diseases. By the end of the project, these panels were already being used by three collaborative projects on the UC Davis campus. Work continues as the scientists develop another 200 markers in the same manner. The researchers in this project act as sort of middlemen between the researchers who are isolating and mapping genetic markers to help complete the map of the canine genome, and those who are using the markers to develop diagnostic tests for specific diseases. Ultimately, these tests will aid in the detection of disease carriers and allow breeders to make informed breeding decisions. Researchers in this project mapped genetic markers and identified 100 that are the most optimal for accurate linkage analysis studies.

Publication(s)

Irion, D. N. (2003). Analysis of Genetic Variation in 28 Dog Breed Populations With 100 Microsatellite Markers. Journal of Heredity, 94(1), 81–87. https://doi.org/10.1093/jhered/esg004

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