2032: Y-Chromosome Haplotype Analysis in the Dog

Grant Status: Closed

Grant Amount: $44,227
Dr. Danika L Bannasch, DVM PhD, University of California, Davis
July 18, 2000 - September 30, 2002
Breed(s): -All Dogs
Research Program Area: Prevention

Abstract

Gender is determined by a single pair of chromosomes referred to as sex chromosomes. Females have two X-chromosomes and males have one X chromosome and one Y Chromosome. The Y chromosome is inherited intact from sire to male offspring and therefore represents the male line of descent. It is postulated that domestic dogs have originated from relatively few founders, i.e. select males. This founder effect may be much more evident in individual breeds, which were founded, or heavily influenced, by distinctive sires. We would like to identify markers on the Y chromosome that will allow us to investigate the relatedness of different dog breeds to each other and the diversity that exists within breeds, understanding the diversity that exists within a breed is important for evaluating the heritability of the diseases and the feasibility of eliminating those disorders.

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