Research Portfolio

We invite you to learn about the Foundation's research grants. The search feature and the table below represent the Foundation's complete research portfolio. You may search the complete list of grants by status (open/active or closed/inactive), research program area, and disease.

If you are interested in a specific research program area, browse the recently funded research by program area.

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03186-A: Comparison of Genomic Mutation Status Between Primary Site and Metastatic Lymph Node in Canine Oral Malignant Melanoma University of Missouri Yoshimi Iwaki, DVM Open Oncology
03228: Identification of Tumor-Specific Proteins for Targeted Therapy in Solid and Disseminated Histiocytic Sarcoma University of Zurich Enni Markkanen, Dr. med. vet., Dr. sc. nat. Open Oncology
3195: Early Genetic Markers of Histiocytic Sarcoma for Faster Diagnosis and More Effective Treatment CNRS - University of Rennes Benoit Hedan, DVM, PhD Open Oncology
03121: Optimizing HITI CRISPR/Cas9 Gene Editing for Treating Defective Pyruvate Dehydrogenase Kinase 4 in Doberman Pinschers University of Florida Christopher J Martyniuk, PhD Open Cardiology
03103: Identification of Genetic Mutations in AnalSac Carcinoma Development in English Cocker Spaniels, Part II – Validation University of Georgia Shaying Zhao, PhD Open Oncology
03100-A: The Use of Artificial Intelligence and Computed Tomography Image Features to Predict Sentinel Lymph Node Metastasis in Dogs with Oral Tumours Ontario Veterinary College Christopher Pinard, DVM Open Oncology
02992-A: Sentinel Lymph Node Mapping for Dogs with Lung Tumors University of Guelph Michelle Oblak, DVM, DVSc Open Oncology
03017: Molecular Characterization of Canine Soft Tissue Sarcomas Using Spatially Defined Proteomics and Transcriptomics University of Zurich Enni Markkanen, Dr. med. vet., Dr. sc. nat. Open Oncology
03009: Evaluating Accuracy for Identification of Sentinel Lymph Nodes in Dogs with Cutaneous MCT: A Comparison University of Florida Judith Bertran, DVM, MS and Natalie Worden, DVM Open Oncology
03019: Evaluation of a Targeted Anti αvβ3 Integrin Near-InfraRed (NIR-) Dye for Controlled Resection of Naturally Occurring Soft Tissue Sarcomas in Dogs University of Zurich Mirja Nolff, Dr. med. vet., DVM Open Oncology - Osteosarcoma, Oncology
02987: It’s All In The Genes: The Mutational Landscape of Acute Myeloid Leukemia in Dogs Cornell University Tracy Stokol, BVSc, PhD Open Blood Disorders, Oncology
02907: Ultrasound-guided Histotripsy Ablation of Canine Brain Tumors through an Acoustically Transparent Cranial Window Virginia-Maryland Regional College of Veterinary Medicine John Rossmeisl, DVM, MS Open Oncology
02880: Enhanced Surgical Margin Imaging with Polarization-sensitive Optical Coherence Tomography in Canine Soft Tissue Sarcoma and Mammary Tumors The Ohio State University Laura Selmic, BVetMed, MPH Open Oncology
02858-A: Investigation of Mechanisms of Resistance to Immunotherapy in Dogs with Spontaneous High-grade Glioma University of Minnesota Susan Arnold, DVM Closed Oncology
02879: Use of CRISPR-based Genome-wide Approach for Identification of Vulnerabilities in Canine Oral Melanoma R(D)SVS and Roslin Institute, University of Edinburgh Maciej Parys, DVM, PhD Open Oncology
02910: Open-Label, Phase-2 Clinical Trial of Chlorambucil and Toceranib for Canine Mast Cell Tumors Colorado State University Kristen Weishaar, DVM, MS Open Oncology
02920: Continued Investigation into Tumor-permissive Collagen Signatures in Canine Mammary Gland Tumors: Development of Prognostic Markers and Targeted Therapies for Improved Outcomes University of Pennsylvania Susan W. Volk, VMD, PhD Open Oncology
02855-A: Repurposing Drugs to Modulate Myeloid-derived Suppressor Cells (MDSCs) in Canine Soft Tissue Sarcomas Louisiana State University Sita Withers, BVSc, PhD Open Oncology
02759-T: Reprogramming the Tumor Immune Niche in Canine Hemangiosarcoma University of Florida Jong Hyuk Kim, DVM, PhD Closed Oncology - Hemangiosarcoma
02758: Optical Coherence Tomography for Margin Evaluation of Canine Skin and Subcutaneous Neoplasms The Ohio State University Laura Selmic, BVetMed, MPH Closed Oncology
02772: Identifying Early Stage Ultra-rare Mutations as Predictive Biomarkers of Lymphoma in High-risk versus Low-risk Breeds Within the Dog Aging Project University of Washington Daniel Promislow, PhD Closed Oncology - Lymphoma
02773: Histotripsy for Treatment of Canine Appendicular Osteosarcoma Virginia-Maryland Regional College of Veterinary Medicine Joanne Tuohy, DVM, PhD Closed Oncology - Osteosarcoma
02746-A: Evaluation of Serum miRNA as a Diagnostic Tool for Canine Splenic Hemangiosarcoma University of Georgia Janet Grimes, DVM, MS Closed Oncology - Hemangiosarcoma
02780: Bladder Carcinogen Exposures in Pet Dogs University of Wisconsin, Madison Lauren Trepanier, DVM, PhD Closed Oncology
02782: Genetic Contribution to Early-onset Osteosarcoma University of Wisconsin, Madison Susannah Sample, DVM, MS, PhD Open Oncology - Osteosarcoma
02783: Transcriptional Profiling of Canine Soft Tissue Sarcoma Cornell University Andrew D. Miller, DVM Closed Oncology
02739-A: The Role of the Putative Tumor Suppressor Gene SETD2 in Canine Diffuse Large B-cell Lymphoma Michigan State University Bonnie Harrington, DVM, PhD Closed Oncology - Lymphoma
02751-A: Luteinizing Hormone Receptor Activation Induces Migration and Adhesion in Neoplastic Canine Lymphocytes Oregon State University Michelle Kutzler, DVM, PhD Closed Oncology - Lymphoma
02732-A: Tumor-educated Platelets: A Novel Minimally Invasive Liquid Biopsy for Early Cancer Diagnosis Texas A&M AgriLife Research Blanca M. Lupiani, PhD Open Oncology
02534: Clinical Trial for Evaluation of Propranolol and Doxorubicin in the Treatment of Canine Hemangiosarcoma University of Minnesota Erin B. Dickerson, PhD and Antonella Borgatti, DVM, MS Open Oncology - Hemangiosarcoma
02643-A: Examination of the Effects of Cannabidiol on Canine Neoplastic Cell Apoptosis/Autophagy and Potential for Chemotherapy Resistance or Sensitivity Cornell University Joseph J. Wakshlag, DVM, PhD Closed Oncology
02595-A: Defining the Flow Cytometric Characteristics of Normal and Diseased Canine Spleen and Visceral Lymph Nodes University of Minnesota Courtney E. Johnson, DVM Closed Oncology
02642-A: NF-kappaB Inactivation Enhances Apoptosis in Canine Osteosarcoma Cells University of Georgia Travis Laver, VMD, PhD Closed Oncology - Osteosarcoma
02663: Comparative Brain Tumor Consortium (CBTC) Meningioma Pathology Board National Institutes of Health/National Cancer Institute/Center for Cancer Research/Comparative Oncology Program, Cornell University, and University of Pennsylvania Amy LeBlanc, DVM, Andrew Miller, DVM and Molly Church, MS, VMD, PhD Open Oncology
02636-A: Development of RNA in-situ Hybridization to Identify T Regulatory Cells and their Function within the Tumor Microenvironment of Canine Oral Malignant Melanoma University of Florida Sandra M. Bechtel, DVM Closed Oncology
02487: OX40 Checkpoint Molecule Targeted Antibodies for Cancer Immunotherapy in Dogs Colorado State University Steven W. Dow, DVM, PhD Closed Oncology
02522-A: The Investigation of Lypoxigenase-5 Expression in Canine Normal, Hyperplastic and Neoplastic Urinary Bladder Epithelium University of Liverpool Riccardo Finotello, DVM, PhD Closed Oncology
02489: Tumor-permissive Collagen Signatures in Canine Mammary Gland Tumors: Development of Prognostic Markers and Targeted Therapies for Improved Outcomes University of Pennsylvania Susan W. Volk, VMD, PhD Closed Oncology
02502: Precision Medicine for Canine Lymphoma Trustees of the University of Pennsylvania Nicola J Mason, BVetMed, PhD Closed Oncology - Lymphoma
02510-T: Identification of Novel Synthetic Lethal Partners to Optimize PI3K Targeted Therapies in Canine Hemangiosarcoma Tufts University School of Medicine Cheryl A. London, DVM, PhD Closed Oncology - Hemangiosarcoma
02500: Immune Targeting of the V600E B-Raf Neoantigen in Canine Urothelial Carcinoma University of Pennsylvania Nicola J Mason, BVetMed, PhD Closed Oncology
02519: Prevalence of Bartonella spp. Infection in Dogs with Cardiac and Splenic Hemangiosarcomas within and between Geographic Locations North Carolina State University Edward B Breitschwerdt, DVM; Matthew Breen, PhD Closed Tick-Borne Disease Initiative , Oncology - Hemangiosarcoma
02456-A: The Impact of Intravenous Anesthetic Agents on Canine Natural Killer Cell Trustees of the University of Pennsylvania Oliver A Garden, BVetMed, PhD Closed Oncology
02455-A: Identification of genetic mutations in anal sac carcinoma in English Cocker Spaniels University of Georgia Shaying Zhao, PhD Closed Oncology
02405-A: Transcriptome Based Diagnostics in Canine Soft Tissue Sarcoma Cornell University Andrew D. Miller, DVM Closed Oncology
02321: Clinical Trial of Procaspase-3 Activator (PAC-1) in Combination with Hydroxyurea for Treatment of Canine Meningioma University of Illinois Timothy M. Fan, DVM, PhD Closed Oncology
02318: Genetic and Environmental Risk for Lymphoma in Boxer Dogs University of Wisconsin, Madison Lauren A. Trepanier, DVM, PhD Closed Oncology - Lymphoma
02316: Genetic Risk Factors for Canine T zone Lymphoma Colorado State University Anne A. Avery, DVM, PhD Closed Oncology - Lymphoma
02317: The Role of Complex Translocations Associated with TP53 Somatic Mutations for Aiding Prognosis of Canine Diffuse Large B cell Lymphoma North Carolina State University Matthew Breen, PhD Closed Oncology - Lymphoma
02309-T: Targeting the Cancer Epigenome: The Effect of Specific Histone Lysine Methyltransferase Inhibition in Canine B-Cell Lymphoma University of Missouri Angela McCleary-Wheeler, DVM, PhD Closed Oncology - Lymphoma

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