02595-A: Defining the Flow Cytometric Characteristics of Normal and Diseased Canine Spleen and Visceral Lymph Nodes

Grant Status: Open

Grant Amount: $14,903
Courtney E. Johnson, DVM; University of Minnesota
May 1, 2019 - April 30, 2020

Sponsor(s):

Breed(s): -All Dogs
Research Program Area: Oncology
Donate to Support this Research Program Area

Abstract

The canine spleen and internal lymph nodes are frequently affected by blood-borne cancer. Flow cytometry (FC) can provide key diagnostic and prognostic information for canine cancer and is a rapid and objective tool while also minimally invasive to the patient. However, the methodology is currently limited by the lack of tissue-specific reference intervals (i.e., what is considered “normal”), and published data on the canine spleen and internal lymph nodes is lacking. In light of these knowledge gaps, the investigators will examine the benefits of flow cytometry in the evaluation of dogs with blood-borne cancer that commonly affects the spleen and internal lymph nodes. Performing flow cytometry on tissues from canine patients presenting to University of Minnesota Veterinary Medical Center will allow identification of tissue- specific reference intervals. The findings may provide for accurate and reliable diagnosis of blood-borne disease, including cancer, in dogs.

Publication(s)

None at this time.

Help Future Generations of Dogs

Participate in canine health research by providing samples or by enrolling in a clinical trial. Samples are needed from healthy dogs and dogs affected by specific diseases.

Learn How to Help

Make an Investment Today:

  • $50
  • $100
  • $250
  • $1000
  • Give Now
Connect With Us:
Get Canine Health News:
Please leave this field empty

© 2018 AKC Canine Health Foundation | Privacy Policy | Site Map

Site by Blackbaud, Inc.

Powered by Blackbaud
nonprofit software