Kidney and Urological Disease Grants
The AKC Canine Health Foundation supports basic science discovery and clinical research into the treatment of renal and urologic disorders through the Kidney and Urological Disease Research Program Area. This program supports research into the pathophysiology of disease, the identification of unique/emerging risk factors for the development of renal disease, genetic/epigenetic/proteomic/metabolomic factors associated with disease development, predictors (biomarkers) of kidney damage and recovery, and identification of potential therapeutic drugs that reduce the pathology associated with disease.
Active Grants:
| 03281-MOU | Kidney Disease in Shetland Sheepdogs |
| 03106 | Clinical Validation of Urinary miR-126 as a Marker of Immune Complex- Mediated Glomerulonephritis in Dogs |
| 03020 | Novel Biomarker and Therapeutic Target for Chronic Kidney Disease in Dogs |
| 03026 | Evaluation of the Efficacy of Antioxidant Treatment on Active Kidney Damage and Oxidative Stress |
| 03021 | Judicious Antibiotic Use in Cases of Canine Pyelonephritis |
| 02807-MOU | Characterization of Renal Disease in Greyhound Dogs |
Previously Awarded Grants:
| 02437-MOU | Characterization of Renal Disease in American Boxer Dogs |
| 02556-MOU | Identification of the Molecular Genetic Cause for Cystinuria in Irish Terriers |
| 02263-MOU | Characterization of Kidney Disease in Dalmatians |
| 01844 | Treatment of Urinary Incontinence with Multipotent Muscle Cells: A Regenerative Medicine Approach to a Common Canine Health Problem |
| 02066 | Identification of Novel Biomarkers and Therapeutic Targets for Chronic Kidney Disease in Dogs |
| 02152 | Translation of MicroRNA into an Early Diagnostic Test for Chronic Kidney Disease |
| 02110-A | Investigating the Effects of an Infusion of Fenoldopam on Kidney Function to Improve Outcomes of Acute Kidney Injury Patients |
| 1766 | Identification and Validation of the Genes That Define Abnormal Development of the Kidney in Dogs |
| 1658 | Early Detection of Chronic Kidney Disease to Prevent Kidney Damage |
| 01354-A | Heritability of Calcium Oxalate Urolithiasis in Miniature Schnauzers |
| 01535-A | DNA Sequence Examination of a Gene Region Associated with Mastiff Cystine Stone Formation |
| 01363-A | Comparison of Vitamin B6 levels in a Breed (the Bichon Frise dog) Predisposed to Calcium Oxalate Stones versus Healthy Dogs |
| 01388-A | Validation of a SNP Haplotype Associated with Mastiff Cystine Stone Formation for Use in Genetic Testing |
| 919 | Molecular Genetic Characterization of Canine Cystinuria for the Development of Carrier Tests |
| 386 | Elucidation of the Genetic Defect in Familial Renal Disease in the Norwegian Elkhound |
| 639 | Molecular Genetic Characterization of Canine Cystinuria for the Development of Carrier Tests |
| 00873-A | Preliminary Disease Gene Mapping of Juvenile Renal Dysplasia in the Boxer Dog |
| 00801-A | Characterization of the Mutation Responsible for Fanconi Syndrome in Basenjis |
| 248 | Use of an Artificial Urethral Sphincter in Dogs with Urethral Sphincter Mechanism Incompetence |
| 460 | Measurement of Acute Phase Reactants as a Diagnostic Tool in Shar-Pei Fever |
| 2458 | Molecular Genetic Characterization of Canine Cystinuria for the Development of Carrier Tests |
| 00311-A | A Continued Molecular Genetic Study of Fanconi Syndrome in Basenjis |
| 2462 | Molecular Genetic Study of Fanconi Syndrome in Basenjis |
| 2020 | Inheritance of Urinary Stone Formation in the Dalmatian |
| 1946 | Molecular Genetic Characterization of Canine Cystinuria for the Development of Carrier Tests |
The AKC Canine Health Foundation funds research in 23 different Research Program Areas for the health of all dogs. These program areas enable the Foundation to create depth in our research portfolio and help us to be responsive to the health concerns of our constituents.
Help Future Generations of Dogs
Participate in canine health research by providing samples or by enrolling in a clinical trial. Samples are needed from healthy dogs and dogs affected by specific diseases.
