Neurology Grants

The AKC Canine Health Foundation supports basic science discovery and clinical research into the treatment of neurological diseases through the Neurology Research Program Area. This program supports research into the molecular and genetic basis of disease, and the identification of potential therapeutics to treat neurologic disorders.

Active Grants:

 02800 Defining the Effect of Genotype, Breed and Age on the Risk of Developing Canine Degenerative Myelopathy and Investigating the Molecular Mechanisms Underlying That Risk
 02790-A Characterization of the Fecal Microbiome in Dogs with Spinal Cord Injury Secondary to Intervertebral Disc Disease (IVDD)
 02802 Clinical Trial of Prevotella histicola Supplementation to Ameliorate Meningoencephalomyelitis of Unknown Origin (MUO)
 02791-A Neurofilament Light Chain Concentration in Dogs with Meningoencephalitis (MUE)
 02658 Characterization of Sensory Neuronal and Muscle Pathology in Canine Degenerative Myelopathy to Identify Targets for Therapeutic Intervention
 02604 Clinical, Pathologic, and Molecular Genetics Investigations of Canine Lysosomal Storage Diseases and Related Diseases
 02589 Genetic Basis of Canine Spinal Abnormalities
 02575-MOU Genetic Basis of Exercise-Induced Collapse in Border Collie Related Breeds
 02535-MOU Clinical and Molecular Genetic Analysis of Juvenile-Onset Laryngeal Paralysis in American Staffordshire Terriers
 02452-A Targeting the T helper Inflammatory Pathway in Meningoencephalomyelitis of Unknown Origin (MUO)
 02157-MOU Genomics of Deafness in the Dalmatian
 02165-MOU Identification of Biomarkers and Therapeutic Targets for Canine Degenerative Myelopathy: The Search for A Cure

Previously Awarded Grants:

 02606 The Genetic Background of Lumbosacral Transitional Vertebrae in Dogs
 02162-MOU Defining The Genetic Foundations of Chiari-Like Malformation and Syringomyelia as a Tool to Better Treat Neuropathic Pain in the Dog
 02387-MOU Hereditary Deafness in Dogs – Genomic Studies in English Setters Using Full Sibling Pairs
 02470-A Proteomic Evaluation of Greyhound Meningoencephalitis: A Model for Neuroinflammation in Other Breeds
 02210 Gene Therapy for Canine Degenerative Myelopathy
 02257 Identification of Genetic Risk Factors for Canine Epilepsy
 02172-MOU Understanding Hereditary Deafness in Dogs
 02249-A Studying the Role of the Gastrointestinal Tract in Canine Epilepsy
 02290-MOU Further Studies to Identify the Mutation Responsible for DUNGd
 2248 Identification of a Novel Juvenile Myoclonic Epilepsy Gene and Its Underlying Disease Mechanism
 02141-A Describing the Kinetic and Kinematic Recovery of Dachshunds with Spinal Cord Injury
 02139-A Development of a Neuromusculoskeletal Computer Simulation Gait Model to Characterize Functional Recovery in Dogs with Intervertebral Disk Herniation
 02143-A Development of a Novel Treatment for Intervertebral Disc Disease
 1985 Defining Novel Drug Targets to Treat Chronic and Neuropathic Pain in the Dog
 1731 A Novel Approach to Understanding How Meningoencephalomyelitis Develops In Dogs
 01975-A Development of a Technique to Treat Nerve and Spinal Cord Damage Through Transplantation of Cells That Support the Repair of Damaged Neurons
 01947-A Relief for Chronic Nerve Pain: A One Medicine Approach
 1455 Identification of Genes That Confer Risk for Inflammation of the Brain
 01928-A A Novel Technique to Reveal the Multiple Genes Associated with Canine Epileptoid Cramping Syndrome
 01865-A Defining the Genes That Cause Fatal Degeneration of the Nervous System
 01467 Understanding Laryngeal Paralysis to Provide Better Treatment
 1592 Investigation into the Genetics of Scottie Cramp: Sequencing of Associated Chromosomal Regions
 1004 Syringomyelia in the Brussels Griffon: Magnetic Resonance Imaging Findings, Clinicopathology, and Prevalence
 927 Gene Discovery in Hereditary Cerebellar Abiotrophy of Scottish Terriers
 925 Identification of Mutations Causing Hereditary Cerebellar Cortical Degeneration in American Staffordshire Terriers and Old English Sheepdogs

The AKC Canine Health Foundation funds research in 23 different Research Program Areas for the health of all dogs. These program areas enable the Foundation to create depth in our research portfolio and help us to be responsive to the health concerns of our constituents.

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Participate in canine health research by providing samples or by enrolling in a clinical trial. Samples are needed from healthy dogs and dogs affected by specific diseases.

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