Neurology Grants
The AKC Canine Health Foundation supports basic science discovery and clinical research into the treatment of neurological diseases through the Neurology Research Program Area. This program supports research into the molecular and genetic basis of disease, and the identification of potential therapeutics to treat neurologic disorders.
Active Grants:
| 03219 | Combining Traditional and Multiomic Approaches to Reveal the Cause and Mechanisms of Canine Dysautonomia |
| 03139 | Riluzole as a Neuroprotectant in Canine Degenerative Myelopathy |
| 03134 | Use of a Service Dog Breeding Program to Unravel the Genetics of Congenital Idiopathic Megaesophagus in German Shepherd Dogs |
| 02943-MOU | Identification of Genetic Risk Factors in Degenerative Myelopathy in German Shepherd Dogs |
| 02790-A | Characterization of the Fecal Microbiome in Dogs with Spinal Cord Injury Secondary to Intervertebral Disc Disease (IVDD) |
| 02800 | Defining the Effect of Genotype, Breed and Age on the Risk of Developing Canine Degenerative Myelopathy and Investigating the Molecular Mechanisms Underlying That Risk |
| 02802 | Clinical Trial of Prevotella histicola Supplementation to Ameliorate Meningoencephalomyelitis of Unknown Origin (MUO) |
| 02658 | Characterization of Sensory Neuronal and Muscle Pathology in Canine Degenerative Myelopathy to Identify Targets for Therapeutic Intervention |
| 02589 | Genetic Basis of Canine Spinal Abnormalities |
Previously Awarded Grants:
| 02535-MOU | Clinical and Molecular Genetic Analysis of Juvenile-Onset Laryngeal Paralysis in American Staffordshire Terriers |
| 02791-A | Neurofilament Light Chain Concentration in Dogs with Meningoencephalitis (MUE) |
| 02452-A | Targeting the T helper Inflammatory Pathway in Meningoencephalomyelitis of Unknown Origin (MUO) |
| 02604 | Clinical, Pathologic, and Molecular Genetics Investigations of Canine Lysosomal Storage Diseases and Related Diseases |
| 02575-MOU | Genetic Basis of Exercise-Induced Collapse in Border Collie Related Breeds |
| 02165-MOU | Identification of Biomarkers and Therapeutic Targets for Canine Degenerative Myelopathy: The Search for A Cure |
| 02606 | The Genetic Background of Lumbosacral Transitional Vertebrae in Dogs |
| 02162-MOU | Defining The Genetic Foundations of Chiari-Like Malformation and Syringomyelia as a Tool to Better Treat Neuropathic Pain in the Dog |
| 02157-MOU | Genomics of Deafness in the Dalmatian |
| 02387-MOU | Hereditary Deafness in Dogs – Genomic Studies in English Setters Using Full Sibling Pairs |
| 02470-A | Proteomic Evaluation of Greyhound Meningoencephalitis: A Model for Neuroinflammation in Other Breeds |
| 02210 | Gene Therapy for Canine Degenerative Myelopathy |
| 02257 | Identification of Genetic Risk Factors for Canine Epilepsy |
| 02172-MOU | Understanding Hereditary Deafness in Dogs |
| 02249-A | Studying the Role of the Gastrointestinal Tract in Canine Epilepsy |
| 02290-MOU | Further Studies to Identify the Mutation Responsible for DUNGd |
| 2248 | Identification of a Novel Juvenile Myoclonic Epilepsy Gene and Its Underlying Disease Mechanism |
| 02139-A | Development of a Neuromusculoskeletal Computer Simulation Gait Model to Characterize Functional Recovery in Dogs with Intervertebral Disk Herniation |
| 02141-A | Describing the Kinetic and Kinematic Recovery of Dachshunds with Spinal Cord Injury |
| 02143-A | Development of a Novel Treatment for Intervertebral Disc Disease |
| 01985 | Defining Novel Drug Targets to Treat Chronic and Neuropathic Pain in the Dog |
| 1731 | A Novel Approach to Understanding How Meningoencephalomyelitis Develops In Dogs |
| 01975-A | Development of a Technique to Treat Nerve and Spinal Cord Damage Through Transplantation of Cells That Support the Repair of Damaged Neurons |
| 01947-A | Relief for Chronic Nerve Pain: A One Medicine Approach |
| 1455 | Identification of Genes That Confer Risk for Inflammation of the Brain |
The AKC Canine Health Foundation funds research in 23 different Research Program Areas for the health of all dogs. These program areas enable the Foundation to create depth in our research portfolio and help us to be responsive to the health concerns of our constituents.
Help Future Generations of Dogs
Participate in canine health research by providing samples or by enrolling in a clinical trial. Samples are needed from healthy dogs and dogs affected by specific diseases.
