Hepatic Disease Grants

The AKC Canine Health Foundation supports basic science discovery and clinical research into the treatment of liver disease through the Hepatic Disease Research Program Area. This program supports research into the pathophysiology of hepatic diseases, as well as the molecular and genetic basis and identification of potential therapeutic drugs that reduce the pathology associated with such diseases.

Active Grants:

 03143 Causative Role of Xenobiotic Exposures in Canine Gallbladder Mucocele Formation
 03113 Investigation of Candidate Genetic Variants for Copper-associated Hepatopathy in the Dalmatian
 03030-A Evaluation of Serum C-reactive Protein as a Noninvasive Biomarker of Inflammation and Disease Severity in Dogs with Gallbladder Mucocele
 02544 Medical Resolution of Gallbladder Mucocele Formation in Dogs

Previously Awarded Grants:

 03028-A Characterizing Immunohistopathology and Serum Immunoglobulin G in Immune-Mediated Chronic Hepatitis Dogs
 02297-MOU Understanding the Genetics of Hepatic Copper Toxicosis in the Dalmatian
 02683 Treatment of Idiopathic Chronic Hepatitis and Copper Associated Hepatopathy in Dogs
 02644-A Evaluation of Gallbladder Motility in Dogs with Hyperlipidemia
 01986 Profiling the Metabolic and Lipid Imbalances that are Causative of Gallbladder Disease in Dogs
 02363-A Platelet Function in Dogs with Chronic Liver Disease
 1601 Identifying the Genetic Cause of Fatal Neonatal Liver Disease
 960 Identification of Genes That Cause Liver Copper Toxicosis
 963 Genotyping Small Breed Dogs with Portosystemic Vascular Anomalies and Microvascular Dysplasia
 01160-A Development of Contract-Enhanced Magnetic Resonance Angiography for the Diagnosis of Congenital Vascular Liver Disease in Dogs
 00851-A The Effect of Physiologic Dexamethasone on Blood Glucose Level in Dogs Following Congenital Portosystemic Shunt Ligation
 00981-A Collecting DNA for Identifying Modifiers of COMMD1 in Bedlington Copper Toxicosis
 00722-A Characterization of Liver Auto-Antibodies in Dogs With Chronic Hepatitis
 00395-A Elevated Serum Alkaline Phosphatase Activity in Scottish Terriers: Benign Hyperphosphatasemia or an Indicator of Disease?
 00696-A Transplenic Portography Using a Single Detector Helical CT: Comparison With Transplenic Portal Scintigraphy and Dual Phase CT Angiography
 00649-A MR Portography of Portosystemic Vascular Anomalies in Dogs
 00607-A Comparison of 99MTcO4 Trans-Splenic Portal Scintigraphy to Per-Rectal Portal Scintigraphy for the Diagnosis of Portosystemic Shunts in Dogs
 00578-A Optimization of a DNA Test for the Deletion Mutation in MURR1 Causing Copper Toxicosis in Bedlington Terriers
 1636 Investigation of Oxidant Stress and Antioxidant Levels in Livers of Dogs Having Congenital Portal Systemic Vascular Anomalies
 1844 Determination of Genetic Relationships Among Yorkshire Terriers With Single Congenital Portosystemic Shunts
 1444 Linkage Analysis Between Canine ATP7B Gene Markers and Heritable Copper Toxicosis in Bedlington Terriers

The AKC Canine Health Foundation funds research in 23 different Research Program Areas for the health of all dogs. These program areas enable the Foundation to create depth in our research portfolio and help us to be responsive to the health concerns of our constituents.

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Participate in canine health research by providing samples or by enrolling in a clinical trial. Samples are needed from healthy dogs and dogs affected by specific diseases.

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