Oncology - Hemangiosarcoma Grants

The Oncology - Hemangiosarcoma Research Program Area is designed to gain a better understanding of the biology and progression of this disease with the goal to design new and effective approaches to treatment.  Since hemangiosarcoma is often not detected or diagnosed until the later stages of the disease, there is a focus for developing advanced diagnostics as well as therapeutic interventions. Hemangiosarcoma is of major concern to the AKC Canine Health Foundation and has prompted the establishment of an Hemangiosarcoma Research Initiative to uniquely address this disease.

Learn about our Hemangiosarcoma Research Initiative!

Active Grants:

 03187 Investigating Volatile Organic Compounds as Potential Markers of Canine Hemangiosarcoma by Trained Bio-detection Dogs
 03011 A GD3 Nano-scaled Liposomal Cancer Vaccine Clinical Trial for Canine Hemangiosarcoma
 03003 Suppression of Extracellular Glutamate Efflux & mGluR1 Signaling to Impede Canine Hemangiosarcoma Cell Growth
 02946 Towards Curative Outcomes in Canine Hemangiosarcoma
 02806-MOU Strategic Prevention of Canine Hemangiosarcoma: Lifetime Follow-Up
 02534 Clinical Trial for Evaluation of Propranolol and Doxorubicin in the Treatment of Canine Hemangiosarcoma

Previously Awarded Grants:

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 02746-A Evaluation of Serum miRNA as a Diagnostic Tool for Canine Splenic Hemangiosarcoma
 02519 Prevalence of Bartonella spp. Infection in Dogs with Cardiac and Splenic Hemangiosarcomas within and between Geographic Locations
 02942 Genome-wide Molecular Interrogation of Canine Hemangiosarcoma
 02864-A Luteinizing Hormone Receptor Activation in Canine Hemangiosarcoma Cells
 02759-T Reprogramming the Tumor Immune Niche in Canine Hemangiosarcoma
 02510-T Identification of Novel Synthetic Lethal Partners to Optimize PI3K Targeted Therapies in Canine Hemangiosarcoma
 02234-MOU A Novel Approach for Prevention of Canine Hemangiosarcoma
 2217 A Novel Mechanism to Regulate the Growth of Canine Hemangiosarcoma
 01759 Disrupting the Differentiation of Cancer Stem Cells to Prevent the Spread of Hemangiosarcoma
 02081-A Integrating Cutting Edge Science with Scientific Training to Defeat Hemangiosarcoma
 01925-A Discovery of Novel Micro-Ribonucleic Acids for Diagnosis and Prognosis of Canine Hemangiosarcoma
 01911-A Enhanced Hemangiosarcoma Therapy Using a Novel Combination of Drugs That Target Tumor Proliferation
 01131 Genetic Background and the Angiogenic Phenotype in Cancer
 01429 Mechanistic Relationship of IL-8 in Cell Proliferation and Survival of Canine Hemangiosarcoma
 1484 Identification and Characterization of a Canine Derived Single Chain Antibody that Binds and Neutralizes Canine VEGF
 01139 Immune Targeting of Canine Hemangiosarcoma Using a Canine Derived Single Chain Antibody Approach
 01355-A Expression of Vascular Endothelial markers in Canine Hemangiosarcoma and their use in Diagnostic Cytology Using Immunocytochemistry
 01147 Identifying Mutations in Genes Associated with Canine Hemangiosarcoma
 01175-A Pilot Investigation of the Causes of Hemangiosarcoma in Clumber Spaniels
 01168-A Identifying Mutations in Genes Associated with Canine Hemangiosarcoma: Denser Fine Mapping of the Associated Locus in Chromosome 5
 00257 Investigation of Predictors of Outcome for Canine Mast Cell Tumors
 00593B Mapping Genes Associated with Canine Hemangiosarcoma
 00593A Mapping Genes Associated with Canine Hemangiosarcoma
 01169-A Identifying Mutations in Genes Associated with Canine Hemangiosarcoma: Denser Fine Mapping of the Associated Locus in Chromosome 26
 422 Tailored Antitumor Vaccines for Canine Hemangiosarcoma

The AKC Canine Health Foundation funds research in 23 different Research Program Areas for the health of all dogs. These program areas enable the Foundation to create depth in our research portfolio and help us to be responsive to the health concerns of our constituents.

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Help Future Generations of Dogs

Participate in canine health research by providing samples or by enrolling in a clinical trial. Samples are needed from healthy dogs and dogs affected by specific diseases.

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