Cardiology Grants

The Cardiology Research Program Area is designed to support integrated basic and clinical research to study normal and abnormal cardiovascular development.  This program supports research in the general areas of:

  • Heart Development
  • Structural Disease
  • Arrhythmias
  • Diagnostics
  • Therapeutics
  • Surgery
  • Enabling Technologies in research discovery
  • Enabling Technologies in drug design and development

Active Grants:

 02632 Canine Chagas Disease: Characterizing Cardiac Disease and Developing Screening Recommendations for Asymptomatic Dogs Seropositive for Trypanosoma cruzi
 02631 Genetic and Metabolic Determinants of Dilated Cardiomyopathy and their Relationship to Cardiac Arrhythmia in Doberman Pinschers
 02649 Three-dimensional Echocardiographic Determinants of the Age of Onset of Myxomatous Mitral Valve Disease in Cavalier King Charles Spaniels
 02661 Investigation into Diet-Associated Dilated Cardiomyopathy in Dogs
 02550 The Role of Bartonella spp. Exposure and Cardiac Genetic Variation on the Clinical Expression of Arrhythmogenic Right Ventricular Cardiomyopathy in the Boxer Dog
 02531 Identification of Genetic Risk Allele(s) Associated with the Development of Tricuspid Valve Dysplasia in the Labrador Retriever
 02436 Predicting Disease Stage and Diuretic Responsiveness in Dogs with Acquired Heart Disease
 02424 Identification of Genetic Variants Associated with Pulmonary Valve Stenosis in Bulldogs through Whole-Genome Sequencing
 02520-MOU Identification of Genetic Markers for Familial Subvalvular Aortic Stenosis in Rottweilers
 02521-MOU Identification of Genetic Markers for Familial Subvalvular Aortic Stenosis in Golden Retrievers

Previously Awarded Grants:

 02163 Is Hypothyroidism a Contributor to Progression of Arrhythmogenic Right Ventricular Cardiomyopathy?
 02160 Identification of Genetic Variants Associated with Myxomatous Mitral Valve Degeneration in the Whippet Dog through Whole-Genome Sequencing
 01982 Personalized Medicine: The Intersection of Genotype and Drug Responsiveness in the Treatment of Canine Pulmonary Hypertension
 02227-MOU Identification of Genetic Markers of Pulmonic Stenosis in Bulldogs
 02147 Use of MicroRNA Profiles in the Serum of Dogs for Early Diagnosis of Mitral Valve Disease and Dilated Cardiomyopathy
 02101 Whole Genome Sequencing for Great Dane Dilated Cardiomyopathy
 02086 Defining the Genetic Basis of Myxomatous Mitral Valve Disease
 01898-A Enhancing Diagnosis and Treatment of Cardiomyopathy through Identification of Biological Markers of Disease
 01849 Filling the Gaps in the Canine Genome
 01753 Identification of Genetic Factors That Alter the Severity of Cardiomyopathy
 01994 Early and Accurate Prediction of Mitral Valve Disease Development
 02098-A Measurement of a Cardiac Muscle Development Protein to Enhance Diagnosis and Prognosis of Cardiomyopathy
 01151 Molecular Basis of Tricuspid Valve Dysplasia
 01866-A Enhancing Treatment of Mitral Valve Disease through the Identification of Biological Markers of Disease
 01859-A Defining the Significance of Irregular Heartbeats through Early Monitoring
 01529-A Platelet, myocardial, and valvular serotonin concentrations in healthy dogs and dogs with mitral valve disease
 01694-A Progression of "Silent" Degenerative Mitral Valve Disease in Norfolk Terriers
 01345-A Circulating Isoforms of B-type Natriuretic Peptide and the Pathogenesis of Canine Heart Failure
 908 Serotonin Type 2A Receptor Antagonist Therapy for Preventing the Progression of Myxomatous Mitral Valve Disease
 01142 Cutting Balloon Valvuloplasty for Dogs with Subaortic Stenosis
 0276 Microarray Analysis for Cardiac Gene Expression in German Shepherd Dogs with Sudden Death
 1428 Inheritance Patterns and Molecular Genetic Analysis of Doberman Pinschers and Boxer Dogs with Familial Dilated Cardiomyopathy

The AKC Canine Health Foundation funds research in 23 different Research Program Areas for the health of all dogs. These program areas enable the Foundation to create depth in our research portfolio and help us to be responsive to the health concerns of our constituents.

Help Future Generations of Dogs

Participate in canine health research by providing samples or by enrolling in a clinical trial. Samples are needed from healthy dogs and dogs affected by specific diseases.

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