Peer-Reviewed Publications Resulting from CHF-funded Grants

We invite you to learn about publications resulting from the Foundation's investments in research. One way CHF measures success in grantmaking is through the production of peer-reviewed publications. CHF-supported research has been published in 218 different peer-reviewed journals, including Nature Genetics and Science and frequently in journals such as the Journal of Veterinary Internal Medicine, Animal Genetics and the American Journal of Veterinary Research.  By consistently funding the most innovative research, the AKC Canine Health Foundation is realizing both small milestones and major breakthroughs in canine health.

You may search the complete list of peer-reviewed publications by research program area, breed and/or disease associated with the grant.

To browse publications by year you may also wish to view our Impact Report.

Research Program Area
Breed:
Disease:
 
Items 1 - 15 of 854  12345678910Next

Grant Number: 02111-A

Research Program Area: Dermatology and Allergic Disease

Evaluating the Contribution of Fungal Infection to the Pathogenesis of Atopic Dermatitis: Putting Evidence under the Use of Antifungal Medication

Meason-Smith, C., Diesel, A., Patterson, A. P., Older, C. E., Mansell, J. M., Suchodolski, J. S., & Rodrigues Hoffmann, A. (2015). What is living on your dog’s skin? Characterization of the canine cutaneous mycobiota and fungal dysbiosis in canine allergic dermatitis. FEMS Microbiology Ecology, 91(12), fiv139. https://doi.org/10.1093/femsec/fiv139

Grant Number: 01236-A

Research Program Area: Endocrinology

Hypothyroidism and AutoImmune Susceptibility Genes in the Bearded Collie

Gershony, L. C., Belanger, J. M., Short, A. D., Le, M., Hytönen, M. K., Lohi, H., … Oberbauer, A. M. (2019). DLA class II risk haplotypes for autoimmune diseases in the Bearded Collie offer insight to autoimmunity signatures across dog breeds. Canine Genetics and Epidemiology, 6(1), 2. https://doi.org/10.1186/s40575-019-0070-7

Gershony, L. C., Belanger, J. M., Hytönen, M. K., Lohi, H., & Oberbauer, A. M. (2019). Novel Locus Associated with Symmetrical Lupoid Onychodystrophy in the Bearded Collie. Genes, 10(9), 635. doi.org/10.3390/genes10090635

Rincon, G., Tengvall, K., Belanger, J. M., Lagoutte,L., Medrano, J. F., André, C., … Oberbauer, A. M. (2011). Comparison of buccaland blood-derived canine DNA, either native or whole genome amplified, forarray-based genome-wide association studies. BMC Research Notes, 4(1),226. https://doi.org/10.1186/1756-0500-4-226

Grant Number: 02161-A

Research Program Area: General Canine Health

Supporting the Evidence-Based Use of Antibiotic Gels after Extensive Dental Plaque Removal in Dogs

Martel, D. P., Fox, P. R., Lamb, K. E., & Carmichael, D. T. (2019). Comparison of closed root planing with versus without concurrent doxycycline hyclate or clindamycin hydrochloride gel application for the treatment of periodontal disease in dogs. Journal of the American Veterinary Medical Association, 254(3), 373–379. https://doi.org/10.2460/javma.254.3.373

Grant Number: 02518

Research Program Area: Behavior

The Effects of Early Life Experience on Working Dog Temperament and Cognition

Bray, E. E., Levy, K. M., Kennedy, B. S., Duffy, D. L., Serpell, J. A., & MacLean, E. L. (2019). Predictive Models of Assistance Dog Training Outcomes Using the Canine Behavioral Assessment and Research Questionnaire and a Standardized Temperament Evaluation. Frontiers in Veterinary Science, 6 (49). https://doi.org/10.3389/fvets.2019.00049

Grant Number: 02529

Research Program Area: General Canine Health

Understanding the Genetics of Adverse Drug Reactions in Sighthounds: Phase II
Mealey, K. L., Martinez, S. E., Villarino, N. F., & Court, M. H. (2019). Personalized medicine: going to the dogs? Human Genetics. https://doi.org/10.1007/s00439-019-02020-w

Martinez, S. E., Shi, J., Zhu, H.-J., Jimenez, T. E. P., Zhu, Z., & Court, M. H. (2019). Absolute quantitation of drug metabolizing cytochrome P450 enzymes and accessory proteins in dog liver microsomes using label-free standard-free analysis reveals inter-breed variability. Drug Metabolism and Disposition, dmd.119.088070. https://doi.org/10.1124/dmd.119.088070

Grant Number: 2242

Research Program Area: General Canine Health

Understanding the Genetics of Adverse Drug Reactions in Sighthounds
Martinez, S. E., Pandey, A. V., & Court, M. H. (2019). Isoform-Dependent Effects of Cytochrome P450 Oxidoreductase Polymorphisms on Drug Metabolism by Cytochrome P450 Enzymes in Dogs. The FASEB Journal, 33(1_supplement), 506.9-506.9. https://doi.org/10.1096/fasebj.2019.33.1_supplement.506.9

Martinez, S. E., Shi, J., Zhu, H.-J., Jimenez, T. E. P., Zhu, Z., & Court, M. H. (2019). Absolute quantitation of drug metabolizing cytochrome P450 enzymes and accessory proteins in dog liver microsomes using label-free standard-free analysis reveals inter-breed variability. Drug Metabolism and Disposition, dmd.119.088070. https://doi.org/10.1124/dmd.119.088070

Grant Number: 02388-MOU

Research Program Area: Cardiology

Genetic Markers for Familial Subvalvular Aortic Stenosis in Newfoundlands
Ontiveros, E. S., Fousse, S. L., Crofton, A. E., Hodge, T. E., Gunther-Harrington, C. T., Visser, L. C., & Stern, J. A. (2019). Congenital Cardiac Outflow Tract Abnormalities in Dogs: Prevalence and Pattern of Inheritance From 2008 to 2017. Frontiers in Veterinary Science, 6. https://doi.org/10.3389/fvets.2019.00052

Grant Number: 02188-A

Research Program Area: Reproductive Conditions

Combined Anti-Mullerian Hormone and Progesterone Testing for the Diagnosis of Canine Ovarian Remnant Syndrome

Place, N. J., Cheraskin, J.-L., & Hansen, B. S. (2019). Evaluation of combined assessments of serum anti-Müllerian hormone and progesterone concentrations for the diagnosis of ovarian remnant syndrome in dogs. Journal of the American Veterinary Medical Association, 254(9), 1067–1072. https://doi.org/10.2460/javma.254.9.1067

Grant Number: 02192-A

Research Program Area: Reproductive Conditions

Advanced Semen Analysis in Labrador Retrievers

Fuente-Lara, A. de la, Hesser, A., Christensen, B., Gonzales, K., & Meyers, S. (2019). Effects from aging on semen quality of fresh and cryopreserved semen in Labrador Retrievers. Theriogenology. https://doi.org/10.1016/j.theriogenology.2019.04.013

Hesser, A., Darr, C., Gonzales, K., Power, H., Scanlan, T., Thompson, J., … Meyers, S. (2017). Semen evaluation and fertility assessment in a purebred dog breeding facility. Theriogenology, 87, 115–123. https://doi.org/10.1016/j.theriogenology.2016.08.012

 

Grant Number: 01075-A

Research Program Area: Dermatology and Allergic Disease

Description and Characterization of a Hair Coat Disorder in Schipperkes

May, E. R., Frank, L. A., & Sula, M.-J. M. (2019). Description and characterization of a hair coat disorder in schipperkes. Veterinary Dermatology, 30(1), 36-e10. https://doi.org/10.1111/vde.12711

Grant Number: 01986

Research Program Area: Hepatic Disease

Profiling the Metabolic and Lipid Imbalances that are Causative of Gallbladder Disease in Dogs

Aicher, K., Cullen, J., Gookin, J., Seiler, G., Lunn, K., Mathews, K., & Correa, M. (2016). HP02 Association of gallbladder mucocele formation with occult hypothyroidism in dogs: A matched case-controlled study. Journal of Veterinary Internal Medicine. 40(4), 1407-1519. https://doi.org/10.1111/jvim.13952

Aicher, K. M., Cullen, J. M., Seiler, G. S., Lunn, K. F., Mathews, K. G., & Gookin, J. L. (2019). Investigation of adrenal and thyroid gland dysfunction in dogs with ultrasonographic diagnosis of gallbladder mucocele formation. PLOS ONE, 14(2), e0212638. https://doi.org/10.1371/journal.pone.0212638

Gookin, J. L., Correa, M. T., Peters, A., Malueg, A., Mathews, K. G., Cullen, J., & Seiler, G. (2015). Association of Gallbladder Mucocele Histologic Diagnosis with Selected Drug Use in Dogs: A Matched Case-Control Study. Journal of Veterinary Internal Medicine, 29(6), 1464-1472. https://doi.org/10.1111/jvim.13649

Gookin, J. L., Mathews, K. G., Cullen, J., & Seiler, G. (2018). Qualitative metabolomics profiling of serum and bile from dogs with gallbladder mucocele formation. PLOS ONE, 13(1), e0191076. https://doi.org/10.1371/journal.pone.0191076

Grant Number: 01557

Research Program Area: Oncology

Narrowing the Search for the Genetic Basis of Histiocytic Malignancies

Kennedy, K., Thomas, R., & Breen, M. (2016). Canine Histiocytic Malignancies—Challenges and Opportunities. Veterinary Sciences, 3(1), 2. https://doi.org/10.3390/vetsci3010002

Kennedy, K., Thomas, R., Durrant, J., Jiang, T., Motsinger-Reif, A., & Breen, M. (2019). Genome-wide DNA copy number analysis and targeted transcriptional analysis of canine histiocytic malignancies identifies diagnostic signatures and highlights disruption of spindle assembly complex. Chromosome Research. https://doi.org/10.1007/s10577-019-09606-0

Grant Number: 01896-A

Research Program Area: Epilepsy Initiative

A Pilot Study: Establishing the Role of Melatonin in the Occurrence of Seizures in Dogs

Thomovsky, S. A., Chen, A. V., Deavila, D. M., & Kiszonas, A. M. (2019). Serum Melatonin Values in Normal Dogs and Dogs with Seizures. Journal of the American Animal Hospital Association. https://doi.org/10.5326/JAAHA-MS-6669

Grant Number: 02152

Research Program Area: Kidney & Urological Disease

Translation of MicroRNA into an Early Diagnostic Test for Chronic Kidney Disease

Chu, C. P., & Nabity, M. B. (2019). Comparison of RNA isolation and library preparation methods for small RNA sequencing of canine biofluids. Veterinary Clinical Pathology, 0(0). https://doi.org/10.1111/vcp.12743

Grant Number: 00257

Research Program Area: Oncology - Hemangiosarcoma

Investigation of Predictors of Outcome for Canine Mast Cell Tumors

Kolicheski, A., Barnes Heller, H. L., Arnold, S., Schnabel, R. D., Taylor, J. F., Knox, C. A., … Katz, M. L. (2017). Homozygous PPT1 Splice Donor Mutation in a Cane Corso Dog With Neuronal Ceroid Lipofuscinosis. Journal of Veterinary Internal Medicine, 31(1), 149–157. https://doi.org/10.1111/jvim.14632

Kolicheski, A., Johnson, G. S., Villani, N. A., O’Brien, D. P., Mhlanga-Mutangadura, T., Wenger, D. A., … Katz, M. L. (2017). GM2 Gangliosidosis in Shiba Inu Dogs with an In-Frame Deletion in HEXB. Journal of Veterinary Internal Medicine, 31(5), 1520–1526. https://doi.org/10.1111/jvim.14794

Villani, N. A., Bullock, G., Michaels, J. R., Yamato, O., O’Brien, D. P., Mhlanga-Mutangadura, T., … Katz, M. L. (2019). A mixed breed dog with neuronal ceroid lipofuscinosis is homozygous for a CLN5 nonsense mutation previously identified in Border Collies and Australian Cattle Dogs. Molecular Genetics and Metabolism. https://doi.org/10.1016/j.ymgme.2019.04.003

Items 1 - 15 of 854  12345678910Next

Help Future Generations of Dogs

Participate in canine health research by providing samples or by enrolling in a clinical trial. Samples are needed from healthy dogs and dogs affected by specific diseases.

Learn How to Help

Help Future Generations of Dogs

Participate in canine health research by providing samples or by enrolling in a clinical trial. Samples are needed from healthy dogs and dogs affected by specific diseases.

Learn How to Help

Make an Investment Today:

  • $50
  • $100
  • $250
  • $1000
  • Give Now
Connect With Us:
Get Canine Health News:
Please leave this field empty

© 2018 AKC Canine Health Foundation | Privacy Policy | Site Map

Site by Blackbaud, Inc.

Powered by Blackbaud
nonprofit software