Oncology Grants

In continuation of CHF’s strong support of canine cancer research, the Oncology Research Program Area remains committed to innovative research that will aid in the discovery of advanced diagnostic technology and therapeutic target identification.

To make sense of the complexity of cancer, new approaches are needed to provide comprehensive characterization of tumors and other canine cancers. These approaches will likely require broad bioinformatic analyses, high throughput methodologies and systems biology tools.

Active Grants:

Previously Awarded Grants:

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 01698-A Immunohistochemical quantification of the transcobalamin II protein and receptor in naturally occurring canine tumors.
 01152 Liposomal Bisphosphonate Therapy for Malignant Histiocytosis
 01336B Finding the Mutations that Increase Susceptibility to Transitional Cell Carcinoma in the Scottish Terrier, West Highland Terrier, and Shetland Sheepdog
 01336A Finding the Mutations that Increase Susceptibility to Transitional Cell Carcinoma in the Scottish Terrier, West Highland Terrier, and Shetland Sheepdog
 01410B Positional Cloning of Histiocytic Sarcoma (HS) in the Bernese Mountain Dog (BMD) and Flat Coated Retriever (Part B - See also 01410A)
 01410A Positional Cloning of Histiocytic Sarcoma (HS) in the Bernese Mountain Dog (BMD) and Flat Coated Retriever (Part A - See also 01410B)
 01093A Positional Cloning of the Gene(s) for Gastric Cancer in the Chow Chow
 00947A Heritable and Sporadic Genetic Lesions in Canine Osteosarcoma
 01384-A Improved Imaging to Monitor Therapy Response of Urinary Bladder Cancer Using 3D Volume Ultrasonography
 01502-A Myxoma Virus Oncolytic Therapy in Mouse Models of Canine Cancer
 01376-A Immunohistochemical Detection of Retinoid Receptor Alpha (RARa) in Naturally Occurring Cases of Cutaneous Mast Cell Tumors in Dogs
 00935A Positional Cloning of Two Genes for Malignant Histiocytosis (MH) in the Bernese Mountain Dog
 00935B Positional Cloning of Two Genes for Malignant Histiocytosis (MH) in the Bernese Mountain Dog
 760 Cellular Genomics - Molecular Cytogenetic Investigation of Canine Soft Tissue Sarcomas
 01194-A Role of Hypoxia-Related Factors in Dog Glioblastoma Invasion
 01064-A Immunocytochemical Detection and siRNA-Mediated Knockdown of Survivin in Canine Lymphoma
 00754B Mapping of the Gene for Transitional Cell Carcinoma in the Scottish Terrier and West Highland White Terrier
 00754A Mapping of the Gene for Transitional Cell Carcinoma in the Scottish Terrier & West Highland White Terrier
 00910-A Epidermal Growth Factor Receptor and Cyclooxygenase-2 Cross-Talk in Canine Mammary Cancers
 01052-A Whole Genome Association Mapping of Squamous Cell Carcinoma (SCC) of the Digit in the Standard Poodle
 822 Canine Comparative Oncology and Genomics Consortium (CCOGC)
 00978-A Isolation of the Canine Telomerase Reverse Transcriptase (TERT) Subunit and Generation of Dominant-Negative Mutants for Telomerase Inhibition
 01029-A Preliminary Pharmacokinetics and Palatability Study of Freeze-Dried Black Raspberries in Healthy Dogs
 349 Genetic Epidemiology of Cancer in the Golden Retriever
 01054-A Adult NeurogenesisA Source of Dog Glioblastoma Multiforme (GBMs) Brain Tumor Development

The AKC Canine Health Foundation funds research in 23 different Research Program Areas for the health of all dogs. These program areas enable the Foundation to create depth in our research portfolio and help us to be responsive to the health concerns of our constituents.

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