Oncology Grants
In continuation of CHF’s strong support of canine cancer research, the Oncology Research Program Area remains committed to innovative research that will aid in the discovery of advanced diagnostic technology and therapeutic target identification.
To make sense of the complexity of cancer, new approaches are needed to provide comprehensive characterization of tumors and other canine cancers. These approaches will likely require broad bioinformatic analyses, high throughput methodologies and systems biology tools.
Active Grants:
Previously Awarded Grants:
| 00754A | Mapping of the Gene for Transitional Cell Carcinoma in the Scottish Terrier & West Highland White Terrier |
| 00910-A | Epidermal Growth Factor Receptor and Cyclooxygenase-2 Cross-Talk in Canine Mammary Cancers |
| 01052-A | Whole Genome Association Mapping of Squamous Cell Carcinoma (SCC) of the Digit in the Standard Poodle |
| 822 | Canine Comparative Oncology and Genomics Consortium (CCOGC) |
| 00978-A | Isolation of the Canine Telomerase Reverse Transcriptase (TERT) Subunit and Generation of Dominant-Negative Mutants for Telomerase Inhibition |
| 01029-A | Preliminary Pharmacokinetics and Palatability Study of Freeze-Dried Black Raspberries in Healthy Dogs |
| 349 | Genetic Epidemiology of Cancer in the Golden Retriever |
| 01054-A | Adult NeurogenesisA Source of Dog Glioblastoma Multiforme (GBMs) Brain Tumor Development |
| 00841-A | Pharmacokinetics and Phase I Clinical Trial of High-Dose Intermittent Oral Artemisinin in Dogs with Spontaneous Tumors |
| 00830-AT | A Pilot Study to Determine the Molecular Characterization of Canine Follicular Thyroid Carcinoma |
| 00896-A | Phase I Clinical Trial and Pharmacokinetics of Intravesical Mytomycin C (MMC) for the Treatment of Canine Transitional Cell Carcinoma (TC) of the Urinary Bladder |
| 00888-A | Generation of Canine Single Chain Fragment Variable Antibody Libraries for the Identification and Targeting of Tumor-Associated Antigens in the Dog |
| 00990-A | Prognostic Indicators for Anal Sac Gland Carcinoma in the English Cocker Spaniel and Preparing to Map Predisposition to this Tumor |
| 00848-A | Evaluation of Neutrophil Function in Treated Tumor-Bearing Dogs |
| 00837-A | Prognostic Significance of Ezrin Expression in Canine High-Grade Soft Tissue Sarcoma |
| 0002646T | Characterization of Receptor Tyrosine Kinase Dysfunction in Malignant Histiocytosis |
| 595 | The Development of a Cellular Delivery System for RNA Interference Targeted to Canine Tumors |
| 0002465T | Identification and Characterization of Genetic Mutations in Canine Mast Cell Tumors |
| 00878-A | MicroRNA Expression in the Domestic Dog and Its Role in Canine Cancer |
| 00336B | Mapping of the Gene for Malignant Histiocytosis in the Bernese Mountain Dog |
| 00336A | Mapping of the Gene for Malignant Histiocytosis in the Bernese Mountain Dog |
| 591 | In Vitro Effects of the Milk Thistle Extract Silibinin in Canine Tumor Cells |
| 678 | Generation and Analysis of Canine Bone Marrow Derived Mast Cells |
| 00825-A | Microarray Analysis of Immune Responses Elicited by CERT + hGMCSF in Dogs With Advanced Cancer |
| 00718-A | Ras Mutations in Canine Lymphoid and Myeloid Leukemias |
The AKC Canine Health Foundation funds research in 23 different Research Program Areas for the health of all dogs. These program areas enable the Foundation to create depth in our research portfolio and help us to be responsive to the health concerns of our constituents.
Help Future Generations of Dogs
Participate in canine health research by providing samples or by enrolling in a clinical trial. Samples are needed from healthy dogs and dogs affected by specific diseases.
