Immunology and Infectious Disease Grants

The Immunology Research Program Area is combined with the Infectious Disease Research Program Area because there is substantial overlap in protection against and resolution of pathogenic infection and immunity against pathogens.  This research seeks to define unique and evolutionarily conserved features of canine immune response pathways and determine how these pathways initiate, sustain, moderate, and resolve immune responses in dogs. 

Active Grants:

 03209 Discovery of Major Antigenic Determinants of Antibody Responses to Colonizing and Infecting Canine Staphylococcus pseudintermedius
 03212-A Wolbachia-targeting qPCR for Detection of Heartworm Infection in Dogs
 03147 Improving Treatment of Canine Blastomycosis through Therapeutic Drug Monitoring
 03137 Targeted Next Generation Sequencing Panel for Comprehensive Testing for Reproductive and Neurologic Pathogens of Dogs
 03087 Epidemiology of Trypanosoma cruzi and Other Vector-borne Pathogens in Hunting Dogs in Virginia and West Virginia
 03118 MicroRNAs as Novel Fluid Biomarkers of Rabies in Naturally Infected Dogs
 03090 Leishmaniasis in Imported Dogs
 03083-A Investigation into the Prevalence and Clinical Significance of Vector-borne Pathogen Coinfections in a Population of Trypanosoma cruzi-infected Dogs from Texas
 03169 Characterization of Hookworm Resistance in Dogs with a Novel Diagnostic Test for Early Intervention
 02986 Catechol O-Methyltransferase as a Molecular Drug Target in Heartworm

Previously Awarded Grants:

Items 1 - 25 of 72  123Next
 02980 Canine Systemic Insecticides as a Novel Intervention to Protect Dogs from Triatomine Insect Vectors of Chagas Disease
 02841 Antigen Discovery for an Improved Serologic Diagnostic of Trypanosoma cruzi Infection in Dogs
 02838 Standardization of rLiNTPDase2 and Derived Chimeras as Antigens on Immunochromatographic Assay for Diagnosis of Canine Visceral Leishmaniasis
 02404-A The Impact of Lidocaine Administration on Natural Killer Cell Populations in Canine Sepsis
 02821-A Investigating the Role of Aedes aegypti in Dog Heartworm Transmission in Communities along the U.S.-Mexico Border
 02681-A Analysis of Canine Herpesvirus Isolates Using Next-Generation Sequencing
 02408 Predicting the Outcome of Coccidioidomycosis in Naturally Infected Dogs
 02633 Validation and Diagnostic Performance of a Novel Monoclonal Antibody based Histoplasma Urine Immunoassay in Dogs with Histoplasmosis
 02448 Canine Chagas Disease: Characterizing Cardiac Abnormalities, Vector Infection and Control Strategies, and Parasite Strains in Kennel Environments
 02532-A Canine Influenza: Occurrence, Spatial and Temporal Trends and Identifying Modifiable Factors to Reduce Transmission at Events in the United States
 02458-A A Laboratory Test for Detecting Drug Resistance in Canine Heartworm Disease
 02380-A Estimating Prevalence and Identifying Risk Factors for Canine Leptospirosis in North America
 02407-A In vitro Efficacy of Nano-sulfur Against Planktonic and Biofilm State of Resistant Bacteria
 02647-A Investigation of Cytokine Biomarkers for the Diagnosis of Canine Tuberculosis
 02441 Evaluation of a New Vaccine for Canine Brucellosis
 02404-A The Impact of Lidocaine Administration on Natural Killer Cell Populations in Canine Sepsis
 02461-A Innate immune response to Leptospira in naturally exposed dogs
 02245-MOU Genetic Predisposition to Avian Tuberculosis in Miniature Schnauzers and Bassets Hounds
 01699-A Preventing Inaccurate Diagnosis of Brucellosis
 02299-A Investigating Recovery of the Skin Microbiota after Surgery
 1771 Defining the Unique Genetic Markers in Dogs That Define Immune Function, Disease Resistance and Tissue Transplantation
 1988 Identification of a Safe Storage Time for Canine Blood Used In the Treatment of Anemia
 2002 Defining the Genetic Basis of Inflammatory Bowel Disease
 02180-A Exploring the Canine Immune System for New Treatments
 02128-A Redefining the Recommendations for Prevention of Infectious Disease at Dog Shows and Other Areas Where Dogs Meet and Compete

The AKC Canine Health Foundation funds research in 23 different Research Program Areas for the health of all dogs. These program areas enable the Foundation to create depth in our research portfolio and help us to be responsive to the health concerns of our constituents.

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