Immunology and Infectious Disease Grants

The Immunology Research Program Area is combined with the Infectious Disease Research Program Area because there is substantial overlap in protection against and resolution of pathogenic infection and immunity against pathogens.  This research seeks to define unique and evolutionarily conserved features of canine immune response pathways and determine how these pathways initiate, sustain, moderate, and resolve immune responses in dogs. 

Active Grants:

 02838 Standardization of rLiNTPDase2 and Derived Chimeras as Antigens on Immunochromatographic Assay for Diagnosis of Canine Visceral Leishmaniasis
 02841 Antigen Discovery for an Improved Serologic Diagnostic of Trypanosoma cruzi Infection in Dogs
 02404-A The Impact of Lidocaine Administration on Natural Killer Cell Populations in Canine Sepsis

Previously Awarded Grants:

 02821-A Investigating the Role of Aedes aegypti in Dog Heartworm Transmission in Communities along the U.S.-Mexico Border
 02681-A Analysis of Canine Herpesvirus Isolates Using Next-Generation Sequencing
 02408 Predicting the Outcome of Coccidioidomycosis in Naturally Infected Dogs
 02633 Validation and Diagnostic Performance of a Novel Monoclonal Antibody based Histoplasma Urine Immunoassay in Dogs with Histoplasmosis
 02448 Canine Chagas Disease: Characterizing Cardiac Abnormalities, Vector Infection and Control Strategies, and Parasite Strains in Kennel Environments
 02532-A Canine Influenza: Occurrence, Spatial and Temporal Trends and Identifying Modifiable Factors to Reduce Transmission at Events in the United States
 02458-A A Laboratory Test for Detecting Drug Resistance in Canine Heartworm Disease
 02407-A In vitro Efficacy of Nano-sulfur Against Planktonic and Biofilm State of Resistant Bacteria
 02380-A Estimating Prevalence and Identifying Risk Factors for Canine Leptospirosis in North America
 02441 Evaluation of a New Vaccine for Canine Brucellosis
 02647-A Investigation of Cytokine Biomarkers for the Diagnosis of Canine Tuberculosis
 02461-A Innate immune response to Leptospira in naturally exposed dogs
 02245-MOU Genetic Predisposition to Avian Tuberculosis in Miniature Schnauzers and Bassets Hounds
 01699-A Preventing Inaccurate Diagnosis of Brucellosis
 02299-A Investigating Recovery of the Skin Microbiota after Surgery
 1771 Defining the Unique Genetic Markers in Dogs That Define Immune Function, Disease Resistance and Tissue Transplantation
 1988 Identification of a Safe Storage Time for Canine Blood Used In the Treatment of Anemia
 2002 Defining the Genetic Basis of Inflammatory Bowel Disease
 02180-A Exploring the Canine Immune System for New Treatments
 02128-A Redefining the Recommendations for Prevention of Infectious Disease at Dog Shows and Other Areas Where Dogs Meet and Compete
 02050 Defining the Genetic Susceptibility to Granulomatous Colitis, a Severe Form of Inflammatory Bowel Disease
 02187-MOU Investigating Symmetrical Lupoid Onychodystrophy in Bearded Collies
 02052 Defining the Mechanism of Severe, Life-Threatening Bleeding Disorders in Dogs
 02102-A Stopping Tick Infestation to Prevent Human and Canine Disease
 2083-A Stemming the Growing Epidemic of Drug Resistant Bacteria

The AKC Canine Health Foundation funds research in 23 different Research Program Areas for the health of all dogs. These program areas enable the Foundation to create depth in our research portfolio and help us to be responsive to the health concerns of our constituents.

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Participate in canine health research by providing samples or by enrolling in a clinical trial. Samples are needed from healthy dogs and dogs affected by specific diseases.

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