One Health is an initiative to improve animal and human health globally through collaboration between veterinarians, physicians, osteopaths, dentists, nurses, and other scientific-health professionals. It recognizes that the health of people is closely connected to the health of animals and our shared environment. The study of emerging infectious diseases, the effects of pollution and antibiotic resistance, the value of the human-animal bond, and more are critical to ensuring optimal health and well-being for all species. To promote One Health, the AKC Canine Health Foundation recognizes and supports research that improves the health of dogs while simultaneously advancing knowledge for human medicine.
CHF-funded studies with a One Health impact are denoted with the following symbol on our website and in our Research Grants Portfolio:
One Health Articles
(courtesy of the Canine Chronicle, June 2021)
Granulomatous Colitis in Boxers and French Bulldogs February 2, 2021
CHF-funded researchers at Cornell University have been studying this disease to identify the underlying genetic mutations and explore the molecular processes involved.
Exploring Risk Factors for Canine Lymphoma September 8, 2020
CHF-funded investigators at the University of Wisconsin, Madison set out to learn more about the combinations of genetic mutations and toxin exposures that contribute to canine lymphoma.
A One Health Approach to Beating Cancer August 27, 2020
Recent discoveries by AKC Canine Health Foundation funded researchers demonstrate the power of a One Health approach in fighting cancer, a devastating disease found in humans and dogs.
CHF-funded researchers concluded that priming of central nervous system immune cells, advancing age, and a mutation in the gene that codes for superoxide dismutase 1 (SOD1) are all risk factors for development of clinical signs of canine DM.
A One Health Approach to Neuronal Ceroid Lipofuscinoses July 15, 2019
CHF-funded researchers are studying a class of rare, fatal disorders of the nervous system called neuronal ceroid lipofuscinoses (NCL). The knowledge gained may help dogs and people affected by this devastating disease.
One Health Research Grants
|02900||Optimizing Storage Conditions of Canine Feces for Fecal Microbiota Transplantation|
|02931||Assessment of Frequency of Seizures and Antiseizure Drug (ASD) Efficacy by Electroencephalography (EEG) for Dogs with Epilepsy|
|02940||Investigating Neuronal Network Connectivity in Dogs with Idiopathic Epilepsy using Functional Magnetic Resonance Imaging|
|02930||A Dose Finding Study of Cannabidiol in Dogs with Idiopathic Epilepsy|
|02921-MOU||Transcriptome Profiling of Canine Familial Dermatomyositis Skin Lesions and Treatment with a JAK Inhibitor to Identify Novel Pathways Involved in Pathogenesis|
|02838||Standardization of rLiNTPDase2 and Derived Chimeras as Antigens on Immunochromatographic Assay for Diagnosis of Canine Visceral Leishmaniasis|
|02875||Canine Pituitary Adenoma Organoids (CaPitO) as in vitro Model for Canine Cushing's Disease|
|02890||Characterizing the LINE-1 Transcriptome in Canine High-grade Peripheral T-cell Lymphoma by RNAseq to Gain Insight into Mechanisms of Drug and Immune Resistance|
|02885||Exposure to Environmental Chemicals in Boxers with Lymphoma|
|02920||Continued Investigation into Tumor-permissive Collagen Signatures in Canine Mammary Gland Tumors: Development of Prognostic Markers and Targeted Therapies for Improved Outcomes|
How to Help
Support CHF-funded research. The knowledge gained will help improve the health of dogs and humans.
Help Future Generations of Dogs
Participate in canine health research by providing samples or by enrolling in a clinical trial. Samples are needed from healthy dogs and dogs affected by specific diseases.