One Health
One Health is an initiative to improve animal and human health globally through collaboration between veterinarians, physicians, osteopaths, dentists, nurses, and other scientific-health professionals. It recognizes that the health of people is closely connected to the health of animals and our shared environment. The study of emerging infectious diseases, the effects of pollution and antibiotic resistance, the value of the human-animal bond, and more are critical to ensuring optimal health and well-being for all species. To promote One Health, the AKC Canine Health Foundation recognizes and supports research that improves the health of dogs while simultaneously advancing knowledge for human medicine.
CHF-funded studies with a One Health impact are denoted with the following symbol on our website and in our Research Grants Portfolio:
Click here to learn more about the One Health Commission.
Explore the November 2021 issue of Human Genetics - a special issue on companion animal genetics which highlights research by several AKC Canine Health Foundation funded investigators.
Resources
One Health Articles
One Health: A Shortcourse
(courtesy of the Canine Chronicle, June 2021)
Health Research Benefits BOTH Ends of the Leash January 25, 2024
Research to understand dog health may also benefit people at the other end of the leash.
The Role of Pollution in Canine Cancer February 7, 2022
Data suggest that air and water pollution influence the development of bladder cancer and lymphoma in dogs.
Exploring New Treatments for Bone Cancer November 15, 2021
Histotripsy shows promise as a non-invasive treatment method for canine osteosarcoma.
Promising Drug Treatment for Brain Tumors September 10, 2021
A novel drug that activates programmed cell death in many cancer cells was well tolerated in dogs and may be effective against meningioma – cancer of the membrane surrounding the brain and spinal cord.
Granulomatous Colitis in Boxers and French Bulldogs February 2, 2021
CHF-funded researchers at Cornell University have been studying this disease to identify the underlying genetic mutations and explore the molecular processes involved.
One Health Research Grants
| 03283 | Investigating the Immune and Cytoreductive Activities of Gilvetmab Alone and in Combination with Indoleamine 2,3-Dioxygenase Inhibition in Canine Urothelial Carcinoma |
| 03300 | Probiotic Prevention of GI Hyperpermeability and Metabolome Disturbances in Dogs with Multicentric Lymphoma Undergoing Multi-drug Chemotherapy |
| 03322-A | Whole Genome Sequencing of 3 Fungal-like Organisms and Development of a Quantitative Real Time Polymerase Chain Reaction (qPCR) for Oomycosis Diagnosis in Dogs |
| 03305-A | TRAF3 as a Novel Prognostic Biomarker in Canine Tumor-associated Macrophages |
| 03313-A | Standardization and Evaluation of the Use of LPG3 Linear Peptides Alone or in Chimera Form for the Serodiagnosis of CVL by ELISA |
| 03294 | Formulation of Radiopharmaceutical Cocktails with MIRDcell AI to Treat B Cell Lymphoma in Dogs |
| 03286 | Single Nucleus RNA Sequencing of Canine Hemangiosarcoma - A Comparative Study of Splenic, Extra-Splenic, and Metastatic Tumor Profiling for Targeted Therapeutic Development |
| 03321-A | Ehrlichiosis and Hemostasis: Uncovering the Molecular Pathophysiology of Perioperative Bleeding in Ehrlichia canis-positive Dogs through Comparative Transcriptomics |
| 03293 | Foundational Studies for Translating FGFR Inhibition in Canine Osteosarcoma |
| 03235 | Prevalence of Heterobilharzia americana in Labrador Retrievers in Texas |
How to Help
Support CHF-funded research. The knowledge gained will help improve the health of dogs and humans.
Help Future Generations of Dogs
Participate in canine health research by providing samples or by enrolling in a clinical trial. Samples are needed from healthy dogs and dogs affected by specific diseases.
