One Health is an initiative to improve animal and human health globally through collaboration between veterinarians, physicians, osteopaths, dentists, nurses, and other scientific-health professionals. It recognizes that the health of people is closely connected to the health of animals and our shared environment. The study of emerging infectious diseases, the effects of pollution and antibiotic resistance, the value of the human-animal bond, and more are critical to ensuring optimal health and well-being for all species. To promote One Health, the AKC Canine Health Foundation recognizes and supports research that improves the health of dogs while simultaneously advancing knowledge for human medicine.
CHF-funded studies with a One Health impact are denoted with the following symbol on our website and in our Research Grants Portfolio:
Explore the November 2021 issue of Human Genetics - a special issue on companion animal genetics which highlights research by several AKC Canine Health Foundation funded investigators.
One Health Articles
(courtesy of the Canine Chronicle, June 2021)
The Role of Pollution in Canine Cancer February 7, 2022
Data suggest that air and water pollution influence the development of bladder cancer and lymphoma in dogs.
Exploring New Treatments for Bone Cancer November 15, 2021
Histotripsy shows promise as a non-invasive treatment method for canine osteosarcoma.
Promising Drug Treatment for Brain Tumors September 10, 2021
A novel drug that activates programmed cell death in many cancer cells was well tolerated in dogs and may be effective against meningioma – cancer of the membrane surrounding the brain and spinal cord.
Granulomatous Colitis in Boxers and French Bulldogs February 2, 2021
CHF-funded researchers at Cornell University have been studying this disease to identify the underlying genetic mutations and explore the molecular processes involved.
Exploring Risk Factors for Canine Lymphoma September 8, 2020
CHF-funded investigators at the University of Wisconsin, Madison set out to learn more about the combinations of genetic mutations and toxin exposures that contribute to canine lymphoma.
One Health Research Grants
|03212-A||Wolbachia-targeting qPCR for Detection of Heartworm Infection in Dogs|
|03215-A||Investigation of the Role of Staphylococcus pseudintermedius Phenol-soluble Modulins in Canine Pyoderma|
|03121||Optimizing HITI CRISPR/Cas9 Gene Editing for Treating Defective Pyruvate Dehydrogenase Kinase 4 in Doberman Pinschers|
|03158||The Associations between Circulating Saturated and Unsaturated Fatty Acids and the Fecal Microbiome and Metabolome with the Development and Severity of Canine Acute Pancreatitis|
|03178-A||Effect of a Canine Systematic Exercise Program on the Dimensions of the Lumbar Paraspinal Musculature and Performance Assessment Scores in Healthy Dogs|
|03172||Identification of Genetic Risk Factors for Gingival Enlargement in Boxers|
|03114||Pain Catastrophizing: A Clinically-relevant Phenomenon in Dogs?|
|03181-A||Characterization of Canine CD39 and CD73 for Use in Regenerative Medicine|
|03162||Fecal Microbiota Transplantation for Treatment of Canine Atopic Dermatitis|
|03147||Improving Treatment of Canine Blastomycosis through Therapeutic Drug Monitoring|
How to Help
Support CHF-funded research. The knowledge gained will help improve the health of dogs and humans.
Help Future Generations of Dogs
Participate in canine health research by providing samples or by enrolling in a clinical trial. Samples are needed from healthy dogs and dogs affected by specific diseases.