One Health
One Health is an initiative to improve animal and human health globally through collaboration between veterinarians, physicians, osteopaths, dentists, nurses, and other scientific-health professionals. It recognizes that the health of people is closely connected to the health of animals and our shared environment. The study of emerging infectious diseases, the effects of pollution and antibiotic resistance, the value of the human-animal bond, and more are critical to ensuring optimal health and well-being for all species. To promote One Health, the AKC Canine Health Foundation recognizes and supports research that improves the health of dogs while simultaneously advancing knowledge for human medicine.
CHF-funded studies with a One Health impact are denoted with the following symbol on our website and in our Research Grants Portfolio:
Click here to learn more about the One Health Commission.
Explore the November 2021 issue of Human Genetics - a special issue on companion animal genetics which highlights research by several AKC Canine Health Foundation funded investigators.
Resources
One Health Articles
One Health: A Shortcourse
(courtesy of the Canine Chronicle, June 2021)
Exploring Risk Factors for Canine Lymphoma September 8, 2020
CHF-funded investigators at the University of Wisconsin, Madison set out to learn more about the combinations of genetic mutations and toxin exposures that contribute to canine lymphoma.
A One Health Approach to Beating Cancer August 27, 2020
Recent discoveries by AKC Canine Health Foundation funded researchers demonstrate the power of a One Health approach in fighting cancer, a devastating disease found in humans and dogs.
The Role of Aging and the Immune System in Canine Degenerative Myelopathy February 18, 2020
CHF-funded researchers concluded that priming of central nervous system immune cells, advancing age, and a mutation in the gene that codes for superoxide dismutase 1 (SOD1) are all risk factors for development of clinical signs of canine DM.
A One Health Approach to Neuronal Ceroid Lipofuscinoses July 15, 2019
CHF-funded researchers are studying a class of rare, fatal disorders of the nervous system called neuronal ceroid lipofuscinoses (NCL). The knowledge gained may help dogs and people affected by this devastating disease.
One Health Research Grants
| 03257 | B cell Subset Analysis Through Spatial Transcriptomics with Application to B cell Disorders |
| 03237 | Impact of Perioperative Antibiotic Prophylaxis on the Intestinal Microbiome in Selected Surgical Procedures |
| 03248 | The Application of Magnetic Resonance Elastography in the Assessment of Dogs with Idiopathic Epilepsy |
| 03189 | Efficacy and Safety of Ripasudil and Nicotinamide for Canine Corneal Endothelial Dystrophy |
| 03261-A | Mechanisms of Immunotolerance in Canine Oral Melanoma: An Opportunity for Comparative Approaches |
| 03259-A | Screening for Genetic Variants Using Whole Exome Sequencing in Dogs with Protein-losing Enteropathy |
| 3195 | Early Genetic Markers of Histiocytic Sarcoma for Faster Diagnosis and More Effective Treatment |
| 03227 | Genetic Testing for Cruciate Ligament Rupture Using Polygenic Risk Score (PRS) Prediction |
| 03209 | Discovery of Major Antigenic Determinants of Antibody Responses to Colonizing and Infecting Canine Staphylococcus pseudintermedius |
| 03194 | A Blueprint to Develop Next-Generation CAR T Therapy for Canine Lymphoma |
How to Help
Support CHF-funded research. The knowledge gained will help improve the health of dogs and humans.
Help Future Generations of Dogs
Participate in canine health research by providing samples or by enrolling in a clinical trial. Samples are needed from healthy dogs and dogs affected by specific diseases.
