One Health is an initiative to improve animal and human health globally through collaboration between veterinarians, physicians, osteopaths, dentists, nurses, and other scientific-health professionals. It recognizes that the health of people is closely connected to the health of animals and our shared environment. The study of emerging infectious diseases, the effects of pollution and antibiotic resistance, the value of the human-animal bond, and more are critical to ensuring optimal health and well-being for all species. To promote One Health, the AKC Canine Health Foundation recognizes and supports research that improves the health of dogs while simultaneously advancing knowledge for human medicine.
CHF-funded studies with a One Health impact are denoted with the following symbol on our website and in our Research Grants Portfolio:
Explore the November 2021 issue of Human Genetics - a special issue on companion animal genetics which highlights research by several AKC Canine Health Foundation funded investigators.
One Health Articles
(courtesy of the Canine Chronicle, June 2021)
A One Health Approach to Beating Cancer August 27, 2020
Recent discoveries by AKC Canine Health Foundation funded researchers demonstrate the power of a One Health approach in fighting cancer, a devastating disease found in humans and dogs.
CHF-funded researchers concluded that priming of central nervous system immune cells, advancing age, and a mutation in the gene that codes for superoxide dismutase 1 (SOD1) are all risk factors for development of clinical signs of canine DM.
A One Health Approach to Neuronal Ceroid Lipofuscinoses July 15, 2019
CHF-funded researchers are studying a class of rare, fatal disorders of the nervous system called neuronal ceroid lipofuscinoses (NCL). The knowledge gained may help dogs and people affected by this devastating disease.
One Health Research Grants
|03139||Riluzole as a Neuroprotectant in Canine Degenerative Myelopathy|
|03053-A||Genome-wide Association Study to Investigate Genetic Markers for Antimicrobial Resistance in Mycoplasma cynos Associated with Canine Infectious Respiratory Disease|
|03137||Targeted Next Generation Sequencing Panel for Comprehensive Testing for Reproductive and Neurologic Pathogens of Dogs|
|03087||Epidemiology of Trypanosoma cruzi and Other Vector-borne Pathogens in Hunting Dogs in Virginia and West Virginia|
|03124||Synbiotic-IgY Modulates MicroRNA Expression and Microbiota in Dogs with Chronic Enteropathy|
|03143||Causative Role of Xenobiotic Exposures in Canine Gallbladder Mucocele Formation|
|03113||Investigation of Candidate Genetic Variants for Copper-associated Hepatopathy in the Dalmatian|
|03118||MicroRNAs as Novel Fluid Biomarkers of Rabies in Naturally Infected Dogs|
|03090||Leishmaniasis in Imported Dogs|
|03095-A||Cell-Specific Expression of MicroRNAs in Primary and Metastatic Canine Osteosarcoma|
How to Help
Support CHF-funded research. The knowledge gained will help improve the health of dogs and humans.
Help Future Generations of Dogs
Participate in canine health research by providing samples or by enrolling in a clinical trial. Samples are needed from healthy dogs and dogs affected by specific diseases.