Oncology - Osteosarcoma Grants

The Oncology - Osteosarcoma Research Program Area remains a focus of the AKC Canine Health Foundation through support of research into the pathophysiology of osteosarcoma, as well as the genetic basis and identification of potential therapeutic drugs.

Active Grants:

 03293 Foundational Studies for Translating FGFR Inhibition in Canine Osteosarcoma
 03262 Dual Energy Computed Tomography and Bone Resorption Markers in Dogs with Appendicular Osteosarcoma Treated with Stereotactic Body Radiation Therapy
 03266-A Development of a Novel Diagnostic Test for Canine Osteosarcoma Using Raman Spectroscopy
 03095-A Cell-Specific Expression of MicroRNAs in Primary and Metastatic Canine Osteosarcoma
 03032-MOU Early Detection of Canine Osteosarcoma
 02991-A Investigating Extracellular Crosstalk Between Canine Osteosarcoma and Macrophages
 02782 Genetic Contribution to Early-onset Osteosarcoma
 01660 Identifying the Genes That Confer Risk for Osteosarcoma

Previously Awarded Grants:

Items 1 - 25 of 30  12Next
 03015 The Immune and Molecular Landscape of Canine Osteosarcoma at the Single-Cell Level
 03019 Evaluation of a Targeted Anti αvβ3 Integrin Near-InfraRed (NIR-) Dye for Controlled Resection of Naturally Occurring Soft Tissue Sarcomas in Dogs
 03000 Characterizing the Immunomodulatory Response of Histotripsy in Canine Osteosarcoma
 02768 Defining the Functional Consequences and Therapeutic Vulnerability of Dystrophin Alterations in Canine Osteosarcoma
 02999 Evaluating Magnetic Resonance Imaging for Quantifying Histotripsy Ablation in Canine Osteosarcoma
 02773 Histotripsy for Treatment of Canine Appendicular Osteosarcoma
 02642-A NF-kappaB Inactivation Enhances Apoptosis in Canine Osteosarcoma Cells
 02215 A Cancer Vaccine for Canine Osteosarcoma
 1806 A Novel Virus-Based Anti-Tumor Treatment for Canine Osteosarcoma
 01949-A Targeting the Cell's Activation Machinery to Halt Tumor Metastasis in Canine Osteosarcoma
 01903-A Defining the Anti-Tumor Activity of Monocytes in Osteosarcoma
 01726-A Identifying Growth Factors That Promote the Spread of Osteosarcoma
 01672-A Isolation and Characterization of Tumor Initiating Cells in Canine Osteosarcoma Cell Lines
 01704-A Expression and distribution of Receptor Activator of Nuclear factor kB Ligand (RANK-L) and its receptor RANK in canine osteosarcoma
 01317 Mutation Detection and Functional Analysis of Multiple Loci for Osteosarcoma
 01542-A The Effects of Baicalein on Canine Osteosarcoma Cells
 01503-A Rational Development of Targeted Therapy - Aurora Kinase Inhibition in Osteosarcoma
 00947B Heritable and Sporadic Genetic Lesions in Canine Osteosarcoma
 982 Evaluation of Efficacy of Fasaret in Dogs with Osteosarcoma
 976 Investigating the Role of STAT3 Activation in Canine Osteosarcoma
 01192-A Metabolism and Action of Gemcitabine in Canine Osteosarcoma Cell Lines
 00757A Hereditary Mutations in Genes Associated with Osteosarcoma in Large Dog Breeds
 778 Role of Regulatory T Cells in Dogs with Osteosarcoma
 01046-A The Relevance of Ezrin in the Metastatic Progression of Canine Osteosarcoma
 00757B Hereditary Mutations in Genes Associated with Osteosarcoma in Large Dog Breeds

The AKC Canine Health Foundation funds research in 23 different Research Program Areas for the health of all dogs. These program areas enable the Foundation to create depth in our research portfolio and help us to be responsive to the health concerns of our constituents.

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