Epilepsy Grants
Epilepsy is the most common veterinary neurologic disease in purebred and mixed-breed dogs. Epilepsy is also a disease where animal and human health concerns intersect as canine epilepsy has been shown to offer a highly suitable model for human epilepsy, offering a On Health approach to addressing the health needs of dogs and their people. These disorders have a wide range of severities, precipitating causes, comorbidities, and treatment outcomes. As such, epilepsy is of major concern to the AKC Canine Health Foundation and has prompted the establishment of an Epilepsy Research Initiative to uniquely address this disease.
Learn about our Epilepsy Research Initiative!
Active Grants:
| 03039 | Prognostic Biomarkers for the Development of Drug Resistance in Dogs with Idiopathic Epilepsy |
| 03040 | Identification of Novel Epilepsy Genes in Dogs |
| 03036-A | Mapping Microstructural Myelin and Axonal Damage in Dogs with Idiopathic Epilepsy using Diffusion MRI and Tract-Based Spatial Statistics |
| 02931 | Assessment of Frequency of Seizures and Antiseizure Drug (ASD) Efficacy by Electroencephalography (EEG) for Dogs with Epilepsy |
| 02940 | Investigating Neuronal Network Connectivity in Dogs with Idiopathic Epilepsy using Functional Magnetic Resonance Imaging |
| 02930 | A Dose Finding Study of Cannabidiol in Dogs with Idiopathic Epilepsy |
Previously Awarded Grants:
| 02561 | Is Gut Dysbiosis Associated with Canine Idiopathic Epilepsy? |
| 02936 | Validating Genetic Variants Underlying Canine Idiopathic Epilepsy and Exploring Their Functional Roles in the Belgian Sheepdog and Tervuren |
| 02792-A | Do Dogs Get Temporal Lobe Epilepsy? Clinical Signs, Magnetic Resonance Imaging and Pathological Findings in Epileptic Dogs |
| 02323 | Efficacy of Cannabidiol (CBD) for the Treatment of Canine Epilepsy |
| 02566 | Genetics of Idiopathic Epilepsy in Labrador Retrievers |
| 02252 | Investigating a Ketogenic Medium-Chain Triglyceride (MCT) Supplement for the Treatment of Drug-Resistant Canine Idiopathic Epilepsy and Its Behavioral Comorbidities |
| 02257 | Identification of Genetic Risk Factors for Canine Epilepsy |
| 02249-A | Studying the Role of the Gastrointestinal Tract in Canine Epilepsy |
| 2248 | Identification of a Novel Juvenile Myoclonic Epilepsy Gene and Its Underlying Disease Mechanism |
| 02131 | Neurostimulation: A Groundbreaking New Treatment for Canine Epilepsy |
| 2133 | Canine Epilepsy: Genetic Variants, Biomarkers, and New Therapies |
| 1615 | Identifying the Genetic Cause of Epilepsy |
| 01896-A | A Pilot Study: Establishing the Role of Melatonin in the Occurrence of Seizures in Dogs |
| 1425 | Identification of Epilepsy-Causing Mutations from the Associated Loci by Next-Generation Resequencing |
| 748 | SNP Association Mapping for Canine Epilepsy |
| 00762 | The Mapping and Characterization of Canine Epilepsy Loci |
| 01005-A | A Pilot Study of Intravenous Levetiracetam for Emergency Treatment of Seizures in Dogs |
| 917 | Genetic Determinants of Canine Epilepsy in the Border Collie and the Staffordshire Bull Terrier |
| 00847-A | Mapping and Identification of the Mutation Responsible for Epilepsy in the Chinook |
| 00886-A | Oral Pregabalin as an Add-on Therapy for Refractory Idopathic Epilepsy in Dogs |
| 00906-A | Development of Pharmacogenetic Markers for Refractoriness to Phenobarbital in Treatment of Canine Epilepsy |
| 598 | Candidate Gene Markers for Epilepsy in Beagles and Other Breeds |
| 266 | Canine Epilepsy: Mapping the Genes and Developing a Linkage Test (Continuing Studies) |
| 224 | Characterizing Idiopathic Epilepsy in the Poodle, Giant Schnauzer, English Mastiff: An Assessment of Inheritance |
| 00653-A | Canine Idiopathic Familial Epilepsies are Associated with Ion Channel Mutations |
The AKC Canine Health Foundation funds research in 23 different Research Program Areas for the health of all dogs. These program areas enable the Foundation to create depth in our research portfolio and help us to be responsive to the health concerns of our constituents.
Help Future Generations of Dogs
Participate in canine health research by providing samples or by enrolling in a clinical trial. Samples are needed from healthy dogs and dogs affected by specific diseases.
