Oncology - Lymphoma Grants
With over 30 different types of known canine lymphomas, the AKC Canine Health Foundation supports canine lymphoma cancer research through our Oncology - Lymphoma Research Program Area. The research program is designed to develop techniques for early diagnosis, increase our understanding of the biology and physiopathology, and identify potential therapeutics.
Active Grants:
| 03194 | A Blueprint to Develop Next-Generation CAR T Therapy for Canine Lymphoma |
| 03144 | Lomustine, Asparaginase, Procarbazine and Prednisone (LAPP) for Canine Multicentric Lymphoma: A Practical Multiagent Chemotherapy Protocol that Avoids Injectable Cytotoxics |
| 03102-A | Can Deep Learning (CNN) Detect Minimal Residual Disease (MRD) in Dogs Treated for Lymphoma? |
| 02998 | Whole-Exome and Transcriptome Sequencing of Canine Small Cell B Cell Lymphoma and Comparative Analysis to Diffuse Large B Cell Lymphoma |
| 03007 | Chimeric BiTE-redirected Anti-viral T Cells for Fratricide of Minimal Residual Disease in T-cell Malignancies |
| 02912 | Adoptive Natural Killer (NK) Cell Immunotherapy for Canine Lymphoma |
| 02885 | Exposure to Environmental Chemicals in Boxers with Lymphoma |
Previously Awarded Grants:
| 02890 | Characterizing the LINE-1 Transcriptome in Canine High-grade Peripheral T-cell Lymphoma by RNAseq to Gain Insight into Mechanisms of Drug and Immune Resistance |
| 02772 | Identifying Early Stage Ultra-rare Mutations as Predictive Biomarkers of Lymphoma in High-risk versus Low-risk Breeds Within the Dog Aging Project |
| 02502 | Precision Medicine for Canine Lymphoma |
| 02739-A | The Role of the Putative Tumor Suppressor Gene SETD2 in Canine Diffuse Large B-cell Lymphoma |
| 02751-A | Luteinizing Hormone Receptor Activation Induces Migration and Adhesion in Neoplastic Canine Lymphocytes |
| 02309-T | Targeting the Cancer Epigenome: The Effect of Specific Histone Lysine Methyltransferase Inhibition in Canine B-Cell Lymphoma |
| 02317 | The Role of Complex Translocations Associated with TP53 Somatic Mutations for Aiding Prognosis of Canine Diffuse Large B cell Lymphoma |
| 02318 | Genetic and Environmental Risk for Lymphoma in Boxer Dogs |
| 1418 | Harnessing a Dog's Own Immune System to Kill Lymphoma Tumor Cells |
| 02316 | Genetic Risk Factors for Canine T zone Lymphoma |
| 02315-A | Discovering Peptide Targets for Development of Adoptive Cell Therapy for Peripheral T-Cell Lymphoma |
| 01918-G | Discovery of Biomarkers to Detect Lymphoma Risk, Classify For Treatment, and Predict Outcome in Golden Retrievers |
| 02304-A | Investigating a Biomarker and Novel Therapeutic Target for Canine Diffuse Large B Cell Lymphoma |
| 1787 | Clinical Advancement of a Cancer Vaccine in Dogs |
| 02092-A | Developing the Use of a Novel Imaging Technique to Define a Dog's Potential Responsiveness to Chemotherapy |
| 1585 | Evaluating a Safer, Less Toxic Radiation Therapy in the Treatment of Lymphoma |
| 01569 | Evaluation of a Novel Drug to Treat Canine Cutaneous Lymphoma |
| 01494-A | Identifying the cause of drug resistance in canine lymphoma |
| 00768 | A Collaborative Study by Veterinary Oncologists, Pathologists and Diagnostic Laboratories to Enhance the Detection, Diagnosis and Treatment of Canine Lymphoma |
| 01651 | Serum Antibody Reactivity Profiling for Canine Lymphoma Detection and Monitoring |
| 01545-A | Pilot Study to Assess Folate Receptor Expression in Canine High-Grade Multicentric Lymphoma |
| 01524-A | Leukocyte Oxidative Burst Activity in Peripheral Blood of Dogs with Lymphoma |
| 01497-A | Dog leukocyte antigen 88 typing in German Shepherd Dogs having pancreatic insufficiency |
| 00613 | The Prognostic Significance of Chromosome Aneuploidy in Canine Lymphoma |
| 00615B | Heritable and Sporadic Genetic Lesions in Canine Lymphoma |
The AKC Canine Health Foundation funds research in 23 different Research Program Areas for the health of all dogs. These program areas enable the Foundation to create depth in our research portfolio and help us to be responsive to the health concerns of our constituents.
Help Future Generations of Dogs
Participate in canine health research by providing samples or by enrolling in a clinical trial. Samples are needed from healthy dogs and dogs affected by specific diseases.
