Oncology - Lymphoma Grants

With over 30 different types of known canine lymphomas, the AKC Canine Health Foundation supports canine lymphoma cancer research through our Oncology - Lymphoma Research Program Area. The research program is designed to develop techniques for early diagnosis, increase our understanding of the biology and physiopathology, and identify potential therapeutics.

Active Grants:

 03194 A Blueprint to Develop Next-Generation CAR T Therapy for Canine Lymphoma
 03144 Lomustine, Asparaginase, Procarbazine and Prednisone (LAPP) for Canine Multicentric Lymphoma: A Practical Multiagent Chemotherapy Protocol that Avoids Injectable Cytotoxics
 03102-A Can Deep Learning (CNN) Detect Minimal Residual Disease (MRD) in Dogs Treated for Lymphoma?
 02998 Whole-Exome and Transcriptome Sequencing of Canine Small Cell B Cell Lymphoma and Comparative Analysis to Diffuse Large B Cell Lymphoma
 03007 Chimeric BiTE-redirected Anti-viral T Cells for Fratricide of Minimal Residual Disease in T-cell Malignancies
 02912 Adoptive Natural Killer (NK) Cell Immunotherapy for Canine Lymphoma
 02885 Exposure to Environmental Chemicals in Boxers with Lymphoma

Previously Awarded Grants:

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 02890 Characterizing the LINE-1 Transcriptome in Canine High-grade Peripheral T-cell Lymphoma by RNAseq to Gain Insight into Mechanisms of Drug and Immune Resistance
 02772 Identifying Early Stage Ultra-rare Mutations as Predictive Biomarkers of Lymphoma in High-risk versus Low-risk Breeds Within the Dog Aging Project
 02502 Precision Medicine for Canine Lymphoma
 02739-A The Role of the Putative Tumor Suppressor Gene SETD2 in Canine Diffuse Large B-cell Lymphoma
 02751-A Luteinizing Hormone Receptor Activation Induces Migration and Adhesion in Neoplastic Canine Lymphocytes
 02309-T Targeting the Cancer Epigenome: The Effect of Specific Histone Lysine Methyltransferase Inhibition in Canine B-Cell Lymphoma
 02317 The Role of Complex Translocations Associated with TP53 Somatic Mutations for Aiding Prognosis of Canine Diffuse Large B cell Lymphoma
 02318 Genetic and Environmental Risk for Lymphoma in Boxer Dogs
 1418 Harnessing a Dog's Own Immune System to Kill Lymphoma Tumor Cells
 02316 Genetic Risk Factors for Canine T zone Lymphoma
 02315-A Discovering Peptide Targets for Development of Adoptive Cell Therapy for Peripheral T-Cell Lymphoma
 01918-G Discovery of Biomarkers to Detect Lymphoma Risk, Classify For Treatment, and Predict Outcome in Golden Retrievers
 02304-A Investigating a Biomarker and Novel Therapeutic Target for Canine Diffuse Large B Cell Lymphoma
 1787 Clinical Advancement of a Cancer Vaccine in Dogs
 02092-A Developing the Use of a Novel Imaging Technique to Define a Dog's Potential Responsiveness to Chemotherapy
 1585 Evaluating a Safer, Less Toxic Radiation Therapy in the Treatment of Lymphoma
 01569 Evaluation of a Novel Drug to Treat Canine Cutaneous Lymphoma
 01494-A Identifying the cause of drug resistance in canine lymphoma
 00768 A Collaborative Study by Veterinary Oncologists, Pathologists and Diagnostic Laboratories to Enhance the Detection, Diagnosis and Treatment of Canine Lymphoma
 01651 Serum Antibody Reactivity Profiling for Canine Lymphoma Detection and Monitoring
 01545-A Pilot Study to Assess Folate Receptor Expression in Canine High-Grade Multicentric Lymphoma
 01524-A Leukocyte Oxidative Burst Activity in Peripheral Blood of Dogs with Lymphoma
 01497-A Dog leukocyte antigen 88 typing in German Shepherd Dogs having pancreatic insufficiency
 00613 The Prognostic Significance of Chromosome Aneuploidy in Canine Lymphoma
 00615B Heritable and Sporadic Genetic Lesions in Canine Lymphoma

The AKC Canine Health Foundation funds research in 23 different Research Program Areas for the health of all dogs. These program areas enable the Foundation to create depth in our research portfolio and help us to be responsive to the health concerns of our constituents.

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Participate in canine health research by providing samples or by enrolling in a clinical trial. Samples are needed from healthy dogs and dogs affected by specific diseases.

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