Musculoskeletal Conditions and Disease Grants

The AKC Canine Health Foundation Musculoskeletal Conditions and Disease Research Program Area supports research aimed at improving the diagnosis, treatment, and prevention of diseases and injuries of the musculoskeletal system and its component tissues.

Active Grants:

 02624  Embracing Polygenicity of Common Complex Disease in Dogs: Genome-wide Association of Cruciate Ligament Rupture
 02589  Genetic Basis of Canine Spinal Abnormalities
 02610-A  The Role of Motilin Signaling in Canine Osteoarthritis
 02646-A  Effect of Hyperthermia on Skeletal Muscle Energy Efficiency
 02400-MOU  Basis of Dwarfism in Great Pyrenees

Previously Awarded Grants:

 02275  Disease Risks Associated with Spay and Neuter: A Breed-Specific, Gender-Specific Perspective
 02229-A  TPLO Surgery and Recovery: A Comparison of Arthroscopy and Arthrotomy
 01828  Mapping of Genetic Risk Factors for Canine Hip Dysplasia
 02078  Development of a Regenerative Medicine Technique to Treat Cartilage Disorders in Dogs
 02226-A  Pilot Clinical Trial to Test the Efficacy of Mesenchymal Stem Cells Over-Expressing IL-10 to Treat Osteoarthritis in Elbows of Senior Dogs
 02142-A  Development of Magnetic Resonance Imaging as a Non-Invasive Tool to Accurately Evaluate Elbow Dysplasia
 2120  Investigating Hypertrophic Osteodystrophy in Weimaraner Dogs
 2109  Studying Hypertrophic Osteodystrophy (HOD) In Irish Setter Dogs
 1762  Use of Plasma-Derived Growth Factors to Heal Cruciate Rupture
 1782  Defining the Elements of Successful Cranial Cruciate Ligament Repair
 01893-A  A Novel, Practical, and Cost-Effective Treatment for Canine Arthritis
 1584  Creation of a Conformation Score to Evaluate Susceptibility to Cranial Cruciate Ligament Disease
 1311  Genome-wide association mapping study of hypertrophic osteodystrophy in Irish Setters
 01901-A  Identifying the Gene Responsible for Dwarfism in Malamutes
 01892-A  Development of Novel Knee Braces As an Alternative to Surgical Intervention in Cranial Cruciate Ligament Disease
 01856-A  Identifying the Best Source of Stem Cells for Treatment of Cranial Cruciate Ligament Disease
 01869-A  Addendum to 1584: Creation of a Conformation Score To Evaluate Susceptibility to Cranial Cruciate Ligament Disease
 1312  Association mapping study of Legg-Calve-Perthes Disease in the West Highland White Terrier, Yorkshire Terrier, and Cairn Terriers
 01718-A  Preventing Osteoarthritis after Elbow Dysplasia Surgery
 01783-A  Mechanical strength of three patella-ligament-tibia allograft fixation techniques for ruptured cranial cruciate ligament repair

The AKC Canine Health Foundation funds research in 23 different Research Program Areas for the health of all dogs. These program areas enable the Foundation to create depth in our research portfolio and help us to be responsive to the health concerns of our constituents.

Help Future Generations of Dogs

Participate in canine health research by providing samples or by enrolling in a clinical trial. Samples are needed from healthy dogs and dogs affected by specific diseases.

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