Hepatic Disease Grants
The AKC Canine Health Foundation supports basic science discovery and clinical research into the treatment of liver disease through the Hepatic Disease Research Program Area. This program supports research into the pathophysiology of hepatic diseases, as well as the molecular and genetic basis and identification of potential therapeutic drugs that reduce the pathology associated with such diseases.
Active Grants:
03143 | Causative Role of Xenobiotic Exposures in Canine Gallbladder Mucocele Formation |
03113 | Investigation of Candidate Genetic Variants for Copper-associated Hepatopathy in the Dalmatian |
03028-A | Characterizing Immunohistopathology and Serum Immunoglobulin G in Immune-Mediated Chronic Hepatitis Dogs |
03030-A | Evaluation of Serum C-reactive Protein as a Noninvasive Biomarker of Inflammation and Disease Severity in Dogs with Gallbladder Mucocele |
02544 | Medical Resolution of Gallbladder Mucocele Formation in Dogs |
Previously Awarded Grants:
02297-MOU | Understanding the Genetics of Hepatic Copper Toxicosis in the Dalmatian |
02683 | Treatment of Idiopathic Chronic Hepatitis and Copper Associated Hepatopathy in Dogs |
02644-A | Evaluation of Gallbladder Motility in Dogs with Hyperlipidemia |
01986 | Profiling the Metabolic and Lipid Imbalances that are Causative of Gallbladder Disease in Dogs |
02363-A | Platelet Function in Dogs with Chronic Liver Disease |
1601 | Identifying the Genetic Cause of Fatal Neonatal Liver Disease |
960 | Identification of Genes That Cause Liver Copper Toxicosis |
963 | Genotyping Small Breed Dogs with Portosystemic Vascular Anomalies and Microvascular Dysplasia |
01160-A | Development of Contract-Enhanced Magnetic Resonance Angiography for the Diagnosis of Congenital Vascular Liver Disease in Dogs |
00851-A | The Effect of Physiologic Dexamethasone on Blood Glucose Level in Dogs Following Congenital Portosystemic Shunt Ligation |
00981-A | Collecting DNA for Identifying Modifiers of COMMD1 in Bedlington Copper Toxicosis |
00722-A | Characterization of Liver Auto-Antibodies in Dogs With Chronic Hepatitis |
00395-A | Elevated Serum Alkaline Phosphatase Activity in Scottish Terriers: Benign Hyperphosphatasemia or an Indicator of Disease? |
00696-A | Transplenic Portography Using a Single Detector Helical CT: Comparison With Transplenic Portal Scintigraphy and Dual Phase CT Angiography |
00649-A | MR Portography of Portosystemic Vascular Anomalies in Dogs |
00607-A | Comparison of 99MTcO4 Trans-Splenic Portal Scintigraphy to Per-Rectal Portal Scintigraphy for the Diagnosis of Portosystemic Shunts in Dogs |
00578-A | Optimization of a DNA Test for the Deletion Mutation in MURR1 Causing Copper Toxicosis in Bedlington Terriers |
1636 | Investigation of Oxidant Stress and Antioxidant Levels in Livers of Dogs Having Congenital Portal Systemic Vascular Anomalies |
1844 | Determination of Genetic Relationships Among Yorkshire Terriers With Single Congenital Portosystemic Shunts |
1444 | Linkage Analysis Between Canine ATP7B Gene Markers and Heritable Copper Toxicosis in Bedlington Terriers |
The AKC Canine Health Foundation funds research in 23 different Research Program Areas for the health of all dogs. These program areas enable the Foundation to create depth in our research portfolio and help us to be responsive to the health concerns of our constituents.
Help Future Generations of Dogs
Participate in canine health research by providing samples or by enrolling in a clinical trial. Samples are needed from healthy dogs and dogs affected by specific diseases.