Ophthalmology Grants

Through the Ophthalmology Research Program Area, the AKC Canine Health Foundation will support basic and clinical research into diseases of the canine eye. Areas of emphasis within this program area include genetics, mechanisms of disease, pathology and molecular interactions important to the eye, and clinical application of research findings to the prevention, diagnosis, and treatment of diseases affecting the eye and visual system.

Active Grants:

 03115 Prolonging Tear Film Stability in Dogs Using a Novel Rabbit Nonpolar Lipid (rNPL593)
 03094-MOU Identification of Gene Mutation Underlying Ocular Melanosis in Cairn Terriers
 02966 Corneal Cross-linking as Treatment for Corneal Ulceration - “Using Light to Save Sight”
 02952 Genetics of X-linked Progressive Retinal Atrophy in Greyhounds
 02963 Genetics of Glaucoma in the Entlebucher Mountain Dog
 02959 Genetic Basis of non-HSF4 Hereditary Cataracts in a Family of Miniature American Shepherds
 02948-A Effect of Glycemic Control on the Onset of Cataract Development in Diabetic Dogs
 02608-T Identification of Genetic Risk Factors for Primary Closed Angle Glaucoma and Pectinate Ligament Abnormality in the Basset Hound
 02569-MOU Development of a Polygenic Risk Model for Pigmentary Uveitis in Golden Retrievers
 02432-A Tears as a Source of Biomarkers for Dry Eye in the Dog

Previously Awarded Grants:

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 02336 Genetics of Primary Angle Closure Glaucoma in American Cocker Spaniels
 02572-MOU Characterization of Retinal Phenotypes and their Association with RPGRIP1 and Modifiers in English Springer Spaniels
 02590-A Histologic characterization of Golden Retriever Pigmentary Uveitis
 02950-A Late-onset Hereditary Cataract in the Boston Terrier: A Whole Genome Sequencing Approach
 02696 Efficacy and Safety of Netarsudil for Canine Corneal Endothelial Dystrophy
 02164-MOU Determining the Genetic Contribution to Boxer Corneal Ulcers
 02340 Clinical and Genetic Background of Progressive Retinal Atrophy in Miniature Schnauzers
 02332-A Identification of Mutations for Primary Lens Luxation in Multiple Dog Breeds
 2061 Emergence of Pigmentary Uveitis as a Potential Cause of Cataracts and Glaucoma
 2336 Genetics of Primary Angle Closure Glaucoma in American Cocker Spaniels
 02243-A Genomic Profiling of Canine Corneal Endothelial Dystrophy
 02105-A The Genetics of Keratoconjunctivitis Sicca in West Highland White Terrier
 2057 Identification of the Genetic Cause of Corneal Ulcers
 02145-A Prevention of Glaucoma and Goniodysgenesis through Genetic Profiling of Disease
 02146-A Development of a Novel Drug Delivery System to Prevent Vision Loss in Canine Cataract Patients
 1594 Identifying the Genes Associated with Glaucoma
 01727-A Emergence of Pigmentary Uveitis as a Potential Cause of Cataracts and Glaucoma
 01874-A Identifying the Genes That Confer Risk for Development of Cataracts
 1612 Regulation of Inflammation to Prevent Cataract Surgery Complications
 01670-A Pinpointing the causal mutation(s) underlying a genome-wide association signal for hereditary cataract in Northern breeds
 1137 Eradication of Cairn Terrier Ocular Melanosis
 747 The Mapping and Characterization of Mutations Responsible for Canine Glaucoma
 972 Identification of Mutations Associated with Hereditary Cataracts in Northern Breeds
 763 Capsular Tension Ring Effect on Canine Lens Epithelial Migration and Post-Operative Lens Capsule Opacification
 642 Investigation of the Genetic Mutations Underlying Progressive Retinal Atrophy

The AKC Canine Health Foundation funds research in 23 different Research Program Areas for the health of all dogs. These program areas enable the Foundation to create depth in our research portfolio and help us to be responsive to the health concerns of our constituents.

 

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Participate in canine health research by providing samples or by enrolling in a clinical trial. Samples are needed from healthy dogs and dogs affected by specific diseases.

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