Participate in Research

Canine health researchers throughout the country are looking for dogs to help them better understand disease. In some cases, you and your dog need to live close to the research institution. In other cases, you can participate no matter where you live. Learn more about the significant impact you can make on canine health research through your participation.

Canine Health Information Center (CHIC) DNA Repository 

The CHIC DNA Repository, co-sponsored by the Orthopedic Foundation for Animals (OFA) and the AKC Canine Health Foundation (CHF), collects and stores canine DNA samples along with corresponding genealogic and phenotypic information to facilitate future research and testing aimed at reducing the incidence of inherited disease in dogs.  DNA samples from any purebred dog may be submitted at any time.  Researchers may then access these samples to be included in their canine health studies.  Learn more at the CHIC website.  
CHICLogo5.15.2018

Clinical Trials

If your dog has recently been diagnosed with a disease, there may be a clinical trial in your area investigating a treatment for that disease.  Enrolling in a clinical trial brings with it a commitment to follow through on therapies and testing. The benefits can include access to cutting-edge medicine and the chance to help future generations of dogs. Use the Individual Research Projects search engine below or review these resources for finding clinical trials.

Sample Submission

The AKC Canine Health Foundation funds canine health research, but does not directly accept samples on behalf of our funded researchers. Biologic sample submission and participation requirements vary by study, so please contact the study center directly to determine which, if any, opportunities match your current situation. Use the Individual Research Projects search engine below to review current opportunities.

Individual Research Projects

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Search for a study by the below criteria to narrow the selection.  More information may be obtained by selecting an individual project. Each study has unique requirements, so please reach out to the listed contact on the linked participation page if you have questions regarding a specific project.

 

Research Area:
Breed:
Type:
 

 


Enhanced surgical margin imaging with polarization-sensitive optical coherence tomography in canine soft tissue sarcoma and mammary tumors

06/14/2021
Breed(s): -All Dogs
Sample Type: Tissue Sample
Study Location: The Ohio State University
CHF-funded Grant: 02880

Clinical evaluation of propranolol in combination with doxorubicin for the treatment of hemangiosarcoma

05/03/2021
Breed(s): -All Dogs
Sample Type: Blood Sample, Clinical Study
Study Location: University of Minnesota, University of Pennsylvania, and Purdue University
CHF-funded Grant: 02534

Understanding the Genetic Basis of Addison's Disease in Portuguese Water Dogs

04/01/2021
Breed(s): Portuguese Water Dog
Sample Type: Blood Sample
Study Location: University of Minnesota
CHF-funded Grant: 02945-MOU

Investigating Neuronal Network Connectivity in Dogs with Idiopathic Epilepsy using Functional Magnetic Resonance Imaging

03/29/2021
Breed(s): -All Dogs
Sample Type: Clinical Study
Study Location: North Carolina State University
CHF-funded Grant: 02940

A Dose Finding Study of Cannabidiol in Dogs with Idiopathic Epilepsy

03/19/2021
Breed(s): -All Dogs
Sample Type: Blood Sample, Clinical Study
Study Location: Colorado State University
CHF-funded Grant: 02930

Transcriptome Profiling of Canine Familial Dermatomyositis (DMS) Skin Lesions and Treatment

02/22/2021
Breed(s): Shetland Sheepdog, Collie
Sample Type: Clinical Study, Tissue Sample
Study Location: University of Georgia
CHF-funded Grant: 02921-MOU

Open-Label, Phase-2 Clinical Trial of Chlorambucil and Toceranib for Canine Mast Cell Tumors

02/12/2021
Breed(s): -All Dogs
Sample Type: Clinical Study
Study Location: Colorado State University
CHF-funded Grant: 02910

Three-dimensional Echocardiographic Determinants of the Age of Onset of Myxomatous Mitral Valve Disease in Cavalier King Charles Spaniels

02/01/2021
Breed(s): Cavalier King Charles Spaniel
Sample Type: Radiographic Study
Study Location: Virginia-Maryland College of Veterinary Medicine
CHF-funded Grant: 02649

Duration of antibiotic therapy for canine superficial pyoderma: Is the one-week post resolution of clinical signs a valid rule-of-thumb?

11/16/2020
Breed(s): -All Dogs
Sample Type: Clinical Study
Study Location: University of Illinois
CHF-funded Grant: 02837

Microbial and Cytokine Signatures of Periodontitis in Dogs

10/05/2020
Breed(s): -All Dogs
Sample Type: Clinical Study, Tissue Sample
Study Location: Cornell University
CHF-funded Grant: 02809

Characterization of Sensory Neuronal and Muscle Pathology in Canine Degenerative Myelopathy to Identify Targets for Therapeutic Intervention

07/01/2020
Breed(s): Pembroke Welsh Corgi, Boxer
Sample Type: Blood Sample, Radiographic Study, Tissue Sample
Study Location: Veterinary Health Center, University of Missouri
CHF-funded Grant: 02658

Genetic Contribution to Early-onset Osteosarcoma

02/25/2020
Breed(s): Irish Wolfhound
Sample Type: Blood Sample
Study Location: University of Wisconsin-Madison
CHF-funded Grant: 02782

Genetic Basis of Canine Spinal Abnormalities

09/29/2019
Breed(s): Icelandic Sheepdog, English Toy Spaniel, Keeshond, Bulldog, Basenji, Shiba Inu, French Bulldog, Norwegian Elkhound, Norwegian Buhund, Pug, Chow Chow, Boston Terrier
Sample Type: DNA Sample
Study Location: Purdue Veterinary Medicine
CHF-funded Grant: 02589

Investigation into Subclinical Diet-Associated Dilated Cardiomyopathy in 4 Dog Breeds

05/08/2019
Breed(s): Miniature Schnauzer, Doberman Pinscher, Golden Retriever
Sample Type: Blood Sample
Study Location: University of Florida
CHF-funded Grant: 02661

Portuguese Water Dog Syndromic Ocular Disease (Microphthalmia)

11/19/2018
Breed(s): Portuguese Water Dog
Sample Type: DNA Sample
Study Location: University of Pennsylvania
CHF-funded Grant: 02403-MOU

Identifying the Genetic Basis of Protein Losing Enteropathy in Yorkshire Terriers

08/16/2018
Breed(s): Yorkshire Terrier
Sample Type: Blood Sample
Study Location: Cornell University College of Veterinary Medicine
CHF-funded Grant: 02523-MOU

Therapeutic gene transfer abrogates canine dilated cardiomyopathy

04/25/2018
Breed(s): Doberman Pinscher
Sample Type: Clinical Study
Study Location: University of Florida Veterinary School
CHF-funded Grant: 01760-T

Towards Curative Outcomes in Canine Hemangiosarcoma

11/15/0021
Breed(s): -All Dogs
Sample Type: Blood Sample, Tissue Sample
Study Location: Ethos Discovery (see website for a list of locations)
CHF-funded Grant: 02946

 

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 *The AKC Canine Health Foundation ensures studies are Institutional Animal Care and Use Committee (IACUC) approved and provide standard informed owner consent information before publicizing requests for participation. Not all projects listed are funded by the AKC Canine Health Foundation and the inclusion of information about studies does not necessarily imply a recommendation for participation. This list is provided as a service to dog owners and breeders.

Help Future Generations of Dogs

Participate in canine health research by providing samples or by enrolling in a clinical trial. Samples are needed from healthy dogs and dogs affected by specific diseases.

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