Peer-Reviewed Publications Resulting from CHF-funded Grants

We invite you to learn about publications resulting from the Foundation's investments in research. One way CHF measures success in grantmaking is through the production of peer-reviewed publications. CHF-supported research has been published in 218 different peer-reviewed journals, including Nature Genetics and Science and frequently in journals such as the Journal of Veterinary Internal Medicine, Animal Genetics and the American Journal of Veterinary Research.  By consistently funding the most innovative research, the AKC Canine Health Foundation is realizing both small milestones and major breakthroughs in canine health.

You may search the complete list of peer-reviewed publications by research program area, breed and/or disease associated with the grant.

To browse publications by year you may also wish to view our Impact Report.

Research Program Area
Breed:
Disease:
 
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Grant Number: 02819

Research Program Area: Tick-Borne Disease Initiative

Identification of Bartonella henselae In Vivo Induced Antigens for Development of a Reliable Serodiagnostic Assay for Canine Bartonelloses

None at this time.

Grant Number: 00722-A

Research Program Area: Hepatic Disease

Characterization of Liver Auto-Antibodies in Dogs With Chronic Hepatitis

None at this time.

Grant Number: 03235

Research Program Area: Immunology and Infectious Disease

Prevalence of Heterobilharzia americana in Labrador Retrievers in Texas

None at this time.

Grant Number: 02631

Research Program Area: Cardiology

Genetic and Metabolic Determinants of Dilated Cardiomyopathy and their Relationship to Cardiac Arrhythmia in Doberman Pinschers

None at this time.

Grant Number: 02703

Research Program Area: Blood Disorders

Resolving the Major Dyslipidemia Phenotypes and Genetic Risk Factors for Familial Hyperlipidemia in Miniature Schnauzers

Tate, N.M.; Underwood, M.; Thomas-Hollands, A.; Minor, K.M.; Cullen, J.N.; Friedenberg, S.G.; Mickelson, J.R.; Xenoulis, P.G.; Steiner, J.M.; Furrow, E. Sequence Analysis of Six Candidate Genes in Miniature Schnauzers with Primary Hypertriglyceridemia. Genes 2024, 15, 193. https://doi.org/10.3390/genes15020193

Grant Number: 03045-A

Research Program Area: Reproductive Conditions

Artificial Intelligence and Machine Learning for Diagnosis of Dog Sperm Morphology

None at this time.

Grant Number: 02175-A

Research Program Area: Reproductive Conditions

Development of a Brucellosis Vaccine for Dogs

Hensel, M. E., Negron, M., & Arenas-Gamboa, A. M. (2018). Brucellosis in Dogs and Public Health Risk. Emerging Infectious Diseases, 24(8), 1401–1406. https://doi.org/10.3201/eid2408.171171

Stranahan, L. W., Chaki, S. P., Garcia-Gonzalez, D. G., Khalaf, O. H., & Arenas-Gamboa, A. M. (2020). Evaluation of the Efficacy of the Brucella canis RM6/66 Δ vjbR Vaccine Candidate for Protection against B. canis Infection in Mice. MSphere, 5(3), e00172-20. https://doi.org/10.1128/mSphere.00172-20.

Grant Number: 1636

Research Program Area: Hepatic Disease

Investigation of Oxidant Stress and Antioxidant Levels in Livers of Dogs Having Congenital Portal Systemic Vascular Anomalies

None at this time.

Grant Number: 02661

Research Program Area: Cardiology

Investigation into Diet-Associated Dilated Cardiomyopathy in Dogs


Brethel, Sara, Seth Locker, Renee Girens, Paulo Rivera, Kathryn Meurs, and Darcy Adin. “The Effect of Taurine Supplementation on the Renin–Angiotensin–Aldosterone System of Dogs with Congestive Heart Failure.” Scientific Reports 13, no. 1 (July 3, 2023): 10700. https://doi.org/10.1038/s41598-023-37978-1.

Adin DB, Hernandez JA. Influence of sex on renin-angiotensin-aldosterone system metabolites and enzymes in Doberman Pinschers. J Vet Intern Med. 2023;37(1): 22‐27. doi:10.1111/jvim.16589

Stepien, RL, Kellihan, HB, Visser, LC, Wenholz, L, Luis Fuentes, V. Echocardiographic values for normal conditioned and unconditioned North American whippets. J Vet Intern Med. 2023; 1- 12. doi:10.1111/jvim.16691

Adin, D., Freeman, L., Stepien, R., Rush, J. E., Tjostheim, S., Kellihan, H., Aherne, M., Vereb, M., & Goldberg, R. (2021). Effect of type of diet on blood and plasma taurine concentrations, cardiac biomarkers, and echocardiograms in 4 dog breeds. Journal of Veterinary Internal Medicine. https://doi.org/10.1111/jvim.16075

Haimovitz, D., Vereb, M., Freeman, L., Goldberg, R., Lessard, D., Rush, J., & Adin, D. (2022). Effect of diet change in healthy dogs with subclinical cardiac biomarker or echocardiographic abnormalities. Journal of Veterinary Internal Medicine. https://doi.org/10.1111/jvim.16416

Adin, D. B., Haimovitz, D., Freeman, L. M., & Rush, J. E. (2022). Untargeted global metabolomic profiling of healthy dogs grouped on the basis of grain inclusivity of their diet and of dogs with subclinical cardiac abnormalities that underwent a diet change. American Journal of Veterinary Research, 83(9). https://doi.org/10.2460/ajvr.22.03.0054

Grant Number: 02400-MOU

Research Program Area: Musculoskeletal Conditions and Disease

Basis of Dwarfism in Great Pyrenees

None at this time.

Grant Number: 02868-A

Research Program Area: Musculoskeletal Conditions and Disease

Characterization of Mesenchymal Stromal Cell Properties of Canine Culture-expanded Articular Chondrocytes
None at this time.

Grant Number: 03321-A

Research Program Area: Immunology and Infectious Disease

Ehrlichiosis and Hemostasis: Uncovering the Molecular Pathophysiology of Perioperative Bleeding in Ehrlichia canis-positive Dogs through Comparative Transcriptomics

None at this time.

Grant Number: 03030-A

Research Program Area: Hepatic Disease

Evaluation of Serum C-reactive Protein as a Noninvasive Biomarker of Inflammation and Disease Severity in Dogs with Gallbladder Mucocele
None at this time.

Grant Number: 03181-A

Research Program Area: Musculoskeletal Conditions and Disease

Characterization of Canine CD39 and CD73 for Use in Regenerative Medicine
Ronald Sluyter, Tahnee B.-D. McEwan, Reece A. Sophocleous, Leanne Stokes, Methods for studying P2X4 receptor ion channels in immune cells, Journal of Immunological Methods, 2024,113626, ISSN 0022-1759, https://doi.org/10.1016/j.jim.2024.113626.

Grant Number: 02441

Research Program Area: Immunology and Infectious Disease

Evaluation of a New Vaccine for Canine Brucellosis

None at this time.

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Participate in canine health research by providing samples or by enrolling in a clinical trial. Samples are needed from healthy dogs and dogs affected by specific diseases.

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