02175-A: Development of a Brucellosis Vaccine for Dogs

Grant Status: Open

Grant Amount: $12,952
Dr. Angela M Arenas, DVM, PhD, Texas A&M AgriLife Research
October 1, 2015 - January 31, 2017
Sponsor(s): American German Shepherd Dog Charitable Foundation, Inc., Siberian Husky Club of America, Inc.
Breed(s): -All Dogs
Research Program Area: Reproductive Conditions and Disease

Abstract

Brucella infections constitute a serious problem for dog breeders, pet owners, and kennels, leading not only to economic costs associated with reproductive loss, but also a public health concern because of the zoonotic potential. The disease, once established, is difficult to control due to the lack of a protective vaccine for canine use. Historically, brucellosis control efforts have demonstrated that the spread of the disease is preventable or significantly reduced in association with vaccination. Unfortunately, efforts to develop a brucellosis vaccine that is safe and effective for dogs have been unsuccessful to date. The goal of this research is to develop a safe and efficacious Brucella canis vaccine using a genetic mutant that has been shown to be safe and efficacious for controlling infection against other Brucella species. The development of a safe and highly protective brucellosis vaccine for dogs will significantly impact canine and human health by limiting the spread of disease.

Publication(s)

None at this time.

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