Peer-Reviewed Publications Resulting from CHF-funded Grants
We invite you to learn about publications resulting from the Foundation's investments in research. One way CHF measures success in grantmaking is through the production of peer-reviewed publications. CHF-supported research has been published in 218 different peer-reviewed journals, including Nature Genetics and Science and frequently in journals such as the Journal of Veterinary Internal Medicine, Animal Genetics and the American Journal of Veterinary Research. By consistently funding the most innovative research, the AKC Canine Health Foundation is realizing both small milestones and major breakthroughs in canine health.
You may search the complete list of peer-reviewed publications by research program area, breed and/or disease associated with the grant.
To browse publications by year you may also wish to view our Impact Report.
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Grant Number: 03194 Research Program Area: Oncology - Lymphoma |
A Blueprint to Develop Next-Generation CAR T Therapy for Canine Lymphoma |
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Grant Number: 02105-A Research Program Area: Ophthalmology |
The Genetics of Keratoconjunctivitis Sicca in West Highland White Terrier None at this time. |
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Grant Number: 2290 Research Program Area: Dermatology and Allergic Disease |
Mapping Canine X Chromosome Linked Alopecia None at this time. |
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Grant Number: 02299-A Research Program Area: Immunology and Infectious Disease |
Investigating Recovery of the Skin Microbiota after Surgery None at this time. |
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Grant Number: 642 Research Program Area: Ophthalmology |
Investigation of the Genetic Mutations Underlying Progressive Retinal Atrophy None at this time. |
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Grant Number: 2616 Research Program Area: Musculoskeletal Conditions and Disease |
Molecular Analysis of Contributory Factors of Osteoarthritis in Canine Hip Dysplasia None at this time. |
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Grant Number: 01363-A Research Program Area: Kidney & Urological Disease |
Comparison of Vitamin B6 levels in a Breed (the Bichon Frise dog) Predisposed to Calcium Oxalate Stones versus Healthy Dogs None at this time. |
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Grant Number: 01672-A Research Program Area: Oncology - Osteosarcoma |
Isolation and Characterization of Tumor Initiating Cells in Canine Osteosarcoma Cell Lines None at this time. |
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Grant Number: 03283 Research Program Area: Oncology |
Investigating the Immune and Cytoreductive Activities of Gilvetmab Alone and in Combination with Indoleamine 2,3-Dioxygenase Inhibition in Canine Urothelial Carcinoma None at this time. |
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Grant Number: 02921-MOU Research Program Area: Dermatology and Allergic Disease |
Transcriptome Profiling of Canine Familial Dermatomyositis Skin Lesions and Treatment with a JAK Inhibitor to Identify Novel Pathways Involved in Pathogenesis None at this time. |
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Grant Number: 03147 Research Program Area: Immunology and Infectious Disease |
Improving Treatment of Canine Blastomycosis through Therapeutic Drug Monitoring
None to date. |
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Grant Number: 02529 Research Program Area: General Canine Health |
Understanding the Genetics of Adverse Drug Reactions in Sighthounds: Phase II Martinez, S. E., Jimenez, T. E. P., & Court, M. H. (2024). Validation of a bupropion, dextromethorphan, and omeprazole cocktail for simultaneous phenotyping of cytochrome P450 2B11, 2D15, and 3A12 activities in dogs. American Journal of Veterinary Research https://doi.org/10.2460/ajvr.24.02.0049 Martinez SE, Pandey AV, Perez Jimenez TE, Zhu Z, Court MH (2024) Pharmacogenomics of poor drug metabolism in greyhounds: Canine P450 oxidoreductase genetic variation, breed heterogeneity, and functional characterization. PLoS ONE 19(2): e0297191. https://doi.org/10.1371/journal.pone.0297191
Mealey, K. L., Martinez, S. E., Villarino, N. F., & Court, M. H. (2019). Personalized medicine: going to the dogs? Human Genetics. https://doi.org/10.1007/s00439-019-02020-w
Martinez, S. E., Shi, J., Zhu, H.-J., Jimenez, T. E. P., Zhu, Z., & Court, M. H. (2019). Absolute quantitation of drug metabolizing cytochrome P450 enzymes and accessory proteins in dog liver microsomes using label-free standard-free analysis reveals inter-breed variability. Drug Metabolism and Disposition, dmd.119.088070. https://doi.org/10.1124/dmd.119.088070 Martinez, S. E., Andresen, M. C., Zhu, Z., Papageorgiou, I., & Court, M. H. (2020). Pharmacogenomics of poor drug metabolism in Greyhounds: Cytochrome P450 (CYP) 2B11 genetic variation, breed distribution, and functional characterization. Scientific Reports, 10(69). doi:10.1038/s41598-019-56660-z |
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Grant Number: 2462 Research Program Area: Kidney & Urological Disease |
Molecular Genetic Study of Fanconi Syndrome in Basenjis None at this time. |
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Grant Number: 01239-A Research Program Area: Reproductive Conditions |
SNP Chip Analyses for Canine Cryptorchidism None at this time. |
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Grant Number: 1836 Research Program Area: Musculoskeletal Conditions and Disease |
Identifying the Genetic Cause of Canine Hip Dysplasia None at this time. |
Help Future Generations of Dogs
Participate in canine health research by providing samples or by enrolling in a clinical trial. Samples are needed from healthy dogs and dogs affected by specific diseases.
Help Future Generations of Dogs
Participate in canine health research by providing samples or by enrolling in a clinical trial. Samples are needed from healthy dogs and dogs affected by specific diseases.
