Immunology and Infectious Disease Grants
The overarching goal of the Immunology Research Program Area is to define unique and evolutionarily conserved features of canine immune response pathways, and to determine how these pathways initiate, sustain, moderate, and resolve immune responses in dogs. This program supports basic science and clinical research into the pathophysiology of immune-mediated disease, the molecular and genetic basis of immune-mediated disease and the identification of potential therapeutic drugs that reduce the pathology associated with immune-mediated disease.
The Immunology Research Program is combined with the Infectious Disease Research Program because there is substantial overlap in protection against and resolution of pathogenic infection and immunity against pathogens.
Recently funded grant titles:
- Using a Novel Diagnostic Test to Guide the Treatment of a Common Fungal Pathogen Encountered by Field Trial and Hunting Dogs
- Understanding Mechanisms Involved in Canine Autoimmune and Inflammatory Disorders
- Stopping Tick Infestation to Prevent Human and Canine Disease
- Stemming the Growing Epidemic of Drug Resistant Bacteria
- Redefining the Recommendations for Prevention of Infectious Disease at Dog Shows and Other Areas Where Dogs Meet and Compete
- Rapid and Accurate Diagnosis of Bacterial Peritonitis
- Preventing Inaccurate Diagnosis of Brucellosis
- Leptospirosis: An Emerging Health Concern for Field Trial and Hunting Dogs
- Investigating Symmetrical Lupoid Onychodystrophy in Bearded Collies
- Investigating Recovery of the Skin Microbiota after Surgery
- Innate immune response to Leptospira in naturally exposed dogs
- Increasing Awareness of Tick-Borne Disease in Dogs Suffering from Immune-Mediated Hemolytic Anemia, Thrombocytopenia and/or Joint Pain through Accurate Diagnosis Of Infection
- Identification of Biological Marker of Idiopathic Immune-Mediated Polyarthropathy to Enable Non-Invasive Diagnosis and Prognosis
- Identification of a Safe Storage Time for Canine Blood Used In the Treatment of Anemia
- Genetic Predisposition to Avian Tuberculosis in Miniature Schnauzers and Bassets Hounds
- Exploring the Canine Immune System for New Treatments
- Estimating Prevalence and Identifying Risk Factors for Canine Leptospirosis in North America
- Documentation of Disease-Causing Ticks in a Field Trial Environment for the Purpose of Developing Practical and Cost-Effective Strategies for Tick Control
- Determining the Effect of Pain Medication on Immune Function: Part 2
- Determining the Effect of Pain Medication on Immune Function: Part 1
The AKC Canine Health Foundation funds research in 18 different Research Program Areas. These program areas enable the Foundation to create depth in our research portfolio and help us to be responsive to the health concerns of our constituents.
Help Future Generations of Dogs
Participate in canine health research by providing samples or by enrolling in a clinical trial. Samples are needed from healthy dogs and dogs affected by specific diseases.