Gastrointestinal Disease Grants

The AKC Canine Health Foundation supports basic science discovery and clinical research into the treatment of gastrointestinal disease through the Gastrointestinal Disease Research Program Area. This program supports research into the pathophysiology of disease, molecular and genetic basis of disease and identification of potential therapeutic drugs that reduce the pathology associated with disease.

Active Grants:

 02523-MOU Identifying the Genetic Basis of Protein Losing Enteropathy in Yorkshire Terriers
 02338 The Genetics of Bloat in German Shepherd Dogs: The Roles of Immune System Genes and the Gut Microbiome
 01935-B Abnormalities in the Stomach's Ability to Contract Predisposes Large-Breed Dogs to Bloat

Previously Awarded Grants:

 01937-B Evaluating the Complex Genetic Basis of Bloat
 02233-A Evaluation of a Novel Technique for Gastric Decompression in Dogs with Gastric Dilatation and Volvulus
 01609 Use of Probiotic to Reduce the Symptoms of Inflammatory Bowel Disease
 01930-A Development of Minimally Invasive Laparoscopic Surgery as a Definitive Diagnostic Tool for Gastrointestinal Obstruction
 01855-A Improving Diagnosis and Treatment of Inflammatory Bowel Disease
 1445 Granulomatous Colitis In Boxer Dogs: Genetic Analysis of Disease and Functional Analysis of Bacterial Killing
 1485 Study of PLE/PLN (Protein-losing Enteropathy/Nephropathy) in Soft-coated Wheaten Terriers
 945 Mucosal Gene Expression Profiles in Canine Inflammatory Bowel Disease
 01341-A Sample Collection, Pedigree Analysis and Candidate Gene Screen for Protein-Losing Enteropathy in Yorkshire Terriers
 01227-A Specificity and Sensitivity of the Pancreatic Lipase Immunoreactivity (SPEC cPL) Test for the Diagnosis of Canine Pancreatitis
 01074-A The Role of Enteropathogenic Bacteria in Diarrhea in Racing Alaskan Sled Dogs
 00871-A Canine Anal Furunculosis
 00870-A Analysis of Pancreatic Acinar Atrophy in the German Shepherd Dog Using the SNP Array
 00803-A Toll-Like Receptors in Dogs And Their Role in Intestinal Inflammation
 00270-A In Vitro Immunosuppressive Effects of Metronidazole on Canine Lymphocytes
 454 Analysis of a Candidate Gene for Pancreatic Acinar Atrophy in the German Shepherd Dog
 2219 Longitudinal Clinical Study, Mode of Inheritance and Therapeutic Trial of Protein-Losing Enteropathy and Nephropathy in Soft Coated Wheaten Terriers
 2232 Cricopharyngeal Dysphagia in the Golden Retriever
 1633 Identification of a Genetic Marker for Pancreatic Acinar Atrophy Causing Exocrine Pancreatic Insufficiency in the German Shepherd Dog
 1873 Sequential Clinical Evaluation, Mode of Inheritance, and Therapeutic Trial of Protein-Losing Enteropathy and Nephropathy in Soft Coated Wheaten Terriers
 1252 A Prospective Study of Morphometric, Genetic & Dietary Risk Factors for Bloat in Dogs
 1285 Mode of Inheritance and Method for Early Detection of Protein-Losing Enteropathy and Nephropathy in Soft Coated Wheaten Terriers

The AKC Canine Health Foundation funds research in 23 different Research Program Areas for the health of all dogs. These program areas enable the Foundation to create depth in our research portfolio and help us to be responsive to the health concerns of our constituents.

Help Future Generations of Dogs

Participate in canine health research by providing samples or by enrolling in a clinical trial. Samples are needed from healthy dogs and dogs affected by specific diseases.

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