1274: Detection of Polymorphism in Comparative Mapping

Grant Status: Closed

Grant Amount: $82,000
Dr. Leslie Lyons, PhD, National Cancer Institute
May 1, 1996 - April 30, 1998
Breed(s): -All Dogs
Research Program Area: Prevention

Project Summary

This project developed 284 genetic markers to be added to the map of the canine genome. Researchers determined that 100 to 150 could be mapped in canine pedigrees, such as the Border Collie and Newfoundland cross developed by Dr. Jasper Rine. In conducting this research, scientists advanced the increasing database of knowledge about the canine genome. This genetic map is essential for locating and identifying the genes causing diseases. The information discovered in this project will provide a tool to assist all researchers that are involved in canine genetics and, eventually, in canine health care, as genetic tests and diagnostic tools are developed.

Publication(s)

- Lyons LA, Kehler JS, O'Brien SJ. Development of comparative anchor tagged sequences (CATS) for canine genome mapping. J Hered. 1999 Jan-Feb;90(1):15-26.

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