Gastrointestinal Disease Grants
The AKC Canine Health Foundation supports basic science discovery and clinical research into the treatment of gastrointestinal disease through the Gastrointestinal Disease Research Program Area. This program supports research into the pathophysiology of disease, molecular and genetic basis of disease and identification of potential therapeutic drugs that reduce the pathology associated with disease.
Active Grants:
| 03158 | The Associations between Circulating Saturated and Unsaturated Fatty Acids and the Fecal Microbiome and Metabolome with the Development and Severity of Canine Acute Pancreatitis |
| 03140 | Efficacy and Tolerability of Gelatin Tannate (Tasectan®) in Canine parvovirus-infected Dogs |
| 03124 | Synbiotic-IgY Modulates MicroRNA Expression and Microbiota in Dogs with Chronic Enteropathy |
| 02899 | How do Maternal, Environmental, and Genetic Factors Contribute to Acquisition and Evolution of the Enteric Microbiome in Dogs? |
| 02859-A | Acute Gastrointestinal Injury in Dogs |
| 02523-MOU | Identifying the Genetic Basis of Protein Losing Enteropathy in Yorkshire Terriers |
Previously Awarded Grants:
| 02900 | Optimizing Storage Conditions of Canine Feces for Fecal Microbiota Transplantation |
| 02742-A | Assessing Microvasculature for Intestinal Viability in Obstructed Small Intestines and Effects of Resection and Anastomosis Techniques |
| 02709 | Identification of Genetic Risk Factors Contributing to Gastrointestinal Motility Disorders |
| 02861-A | Cardiovascular Complications of Acute Pancreatitis in Dogs |
| 02684-A | Evaluation of Serum Zonulin as a Non-invasive Biomarker and Therapeutic Target in Dogs with Chronic Canine Enteropathy |
| 02338 | The Genetics of Bloat in German Shepherd Dogs: The Roles of Immune System Genes and the Gut Microbiome |
| 01935-B | Abnormalities in the Stomach's Ability to Contract Predisposes Large-Breed Dogs to Bloat |
| 01937-B | Evaluating the Complex Genetic Basis of Bloat |
| 02233-A | Evaluation of a Novel Technique for Gastric Decompression in Dogs with Gastric Dilatation and Volvulus |
| 01930-A | Development of Minimally Invasive Laparoscopic Surgery as a Definitive Diagnostic Tool for Gastrointestinal Obstruction |
| 01609 | Use of Probiotic to Reduce the Symptoms of Inflammatory Bowel Disease |
| 01855-A | Improving Diagnosis and Treatment of Inflammatory Bowel Disease |
| 1445 | Granulomatous Colitis In Boxer Dogs: Genetic Analysis of Disease and Functional Analysis of Bacterial Killing |
| 1485 | Study of PLE/PLN (Protein-losing Enteropathy/Nephropathy) in Soft-Coated Wheaten Terriers |
| 945 | Mucosal Gene Expression Profiles in Canine Inflammatory Bowel Disease |
| 01341-A | Sample Collection, Pedigree Analysis and Candidate Gene Screen for Protein-Losing Enteropathy in Yorkshire Terriers |
| 01227-A | Specificity and Sensitivity of the Pancreatic Lipase Immunoreactivity (SPEC cPL) Test for the Diagnosis of Canine Pancreatitis |
| 01074-A | The Role of Enteropathogenic Bacteria in Diarrhea in Racing Alaskan Sled Dogs |
| 00871-A | Canine Anal Furunculosis |
| 00870-A | Analysis of Pancreatic Acinar Atrophy in the German Shepherd Dog Using the SNP Array |
| 00803-A | Toll-Like Receptors in Dogs And Their Role in Intestinal Inflammation |
| 00270-A | In Vitro Immunosuppressive Effects of Metronidazole on Canine Lymphocytes |
| 454 | Analysis of a Candidate Gene for Pancreatic Acinar Atrophy in the German Shepherd Dog |
| 2219 | Longitudinal Clinical Study, Mode of Inheritance and Therapeutic Trial of Protein-Losing Enteropathy and Nephropathy in Soft Coated Wheaten Terriers |
| 2232 | Cricopharyngeal Dysphagia in the Golden Retriever |
The AKC Canine Health Foundation funds research in 23 different Research Program Areas for the health of all dogs. These program areas enable the Foundation to create depth in our research portfolio and help us to be responsive to the health concerns of our constituents.
Help Future Generations of Dogs
Participate in canine health research by providing samples or by enrolling in a clinical trial. Samples are needed from healthy dogs and dogs affected by specific diseases.
