03045-A: Artificial Intelligence and Machine Learning for Diagnosis of Dog Sperm Morphology

Grant Status: Open

Grant Amount: $11,502
Leonardo Brito, DVM, PhD; University of Pennsylvania
July 1, 2022 - June 30, 2023

Sponsor(s):

Breed(s): -All Dogs
Research Program Area: Reproductive Conditions
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Abstract

Sperm morphology evaluation is an important component of dog fertility analysis. However, visual evaluation of sperm morphology is difficult to teach, and results are largely dependent on the proficiency and experience of the evaluator, leading to large variability in results within and across evaluators. The objective of this pilot study is to explore recent advances in artificial intelligence for image pattern recognition, similar to that used by the likes of Google and Facebook, to create an automated method for sperm morphology evaluation. A large database with 10,000 dog sperm images will be created. The images will be evaluated by expert veterinarians, then used to train a Convoluted Neural Network (CNN) using deep learning methods. Investigators expect to generate an algorithm capable of classifying sperm morphology with greater than 90% accuracy and precision. Employing such an algorithm could allow veterinarians to establish more reliable reference values and guidelines for prospective stud dogs and for semen to be used for artificial insemination, improve veterinarian’s abilities to formulate diagnoses and prognoses for infertility problems related to specific sperm defects, and to establish the reproductive safety of drugs and compounds.

Publication(s)

None at this time.

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