02992-A: Sentinel Lymph Node Mapping for Dogs with Lung Tumors
Grant Status: Open
One Health: Yes
Abstract
Canine lung cancer is a devastating disease with minimal progress over the last 20 years. One of the important aspects of staging in dogs with lung cancer is the assessment for lymph node spread. Due to the small size of the lung-associated lymph nodes, these lymph nodes are often not removed at the time of surgery. Specialized techniques that allow for visualization of the lymph nodes before and during surgery can improve treatment methods and the surgical experience, ultimately improving patient treatment and outcomes. The primary objective of this study is to pilot a dual-modality approach to lung sentinel lymph node mapping using computed tomography lymphography (CTL) and indocyanine green (ICG) fluorescence-guided visualization. This novel approach may decrease complications after surgery and provide the most accurate information about metastasis of lung tumors in canine patients.
Publication(s)
None at this time.
Related Grants
- 00978-A: Isolation of the Canine Telomerase Reverse Transcriptase (TERT) Subunit and Generation of Dominant-Negative Mutants for Telomerase Inhibition
- 00888-A: Generation of Canine Single Chain Fragment Variable Antibody Libraries for the Identification and Targeting of Tumor-Associated Antigens in the Dog
Help Future Generations of Dogs
Participate in canine health research by providing samples or by enrolling in a clinical trial. Samples are needed from healthy dogs and dogs affected by specific diseases.
