02829: Investigating the Potential of Phage Therapy to Tackle Staphylococcus pseudintermedius Infections in Dogs
Grant Status: Closed
One Health: Yes
Abstract
The spread of antimicrobial resistance is a major threat to modern medicine, for both humans and animals. In the case of dogs, Staphylococcus pseudintermedius is an important cause of infections, especially pyoderma. Antimicrobial resistance in S. pseudintermedius is making infections more difficult to treat which is affecting dog welfare and might pose a threat to humans too. There is a need to explore alternative treatments to antibiotics with one approach being to use phage therapy. This therapy uses naturally-occurring viruses, called bacteriophages (phages) which infect and kill bacteria to treat bacterial infections. Phage therapy has a long history of safe and effective use in humans and has the advantages that it can target drug resistance bacteria with few side effects. This project has a team of veterinarians and scientists working together to isolate and characterize phages that kill S. pseudintermedius which may contribute to the development of new, exciting treatments to benefit dog health and wellbeing.
Publication(s)
None at this time.
Help Future Generations of Dogs
Participate in canine health research by providing samples or by enrolling in a clinical trial. Samples are needed from healthy dogs and dogs affected by specific diseases.
