02758: Optical Coherence Tomography for Margin Evaluation of Canine Skin and Subcutaneous Neoplasms

Grant Status: Closed

Grant Amount: $43,443
Laura Selmic, BVetMed, MPH; The Ohio State University
March 1, 2020 - August 31, 2022

Sponsor(s): Golden Retriever Foundation, Portuguese Water Dog Foundation

Breed(s): -All Dogs
Research Program Area: Oncology
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Skin cancer is common in older dogs and often requires surgery to treat. For these tumors, the best chance of cure is offered if the surgeon can fully remove both visible and microscopic traces of the tumor. Currently surgeons must rely on pathologist’s assessment of tissues after surgery and the success of the procedure will not be known until several days later. This result is important as residual cancer may need further surgery or other treatments like radiation therapy. Additional treatments such as these can result in further risk and discomfort for dogs as well as be an emotional and financial cost for owners. Optical coherence tomography is an emerging diagnostic imaging tool that uses light waves to generate real-time, high-resolution images of tissue at a microscopic level. These images can be used to evaluate for residual disease at the time of surgery giving immediate feedback to the surgeon. This study will focus on validating this technology for the imaging of surgical margins of canine skin and subcutaneous tumors. If successful, this technology could be used to assess for residual cancer intra-operatively to benefit patients by guiding accurate treatment recommendations.


Cheng, E., Jennings, R. N., Chen, C. L., Biggo, M. R., Erickson, A. K., Dornbusch, J. A., Linn, S. C., Lapsley, J., Alva, B. M., Lorbach, J. N., Premanandan, C., & Selmic, L. E. (2022). Optical coherence tomography for surgical margin evaluation of excised canine cutaneous and subcutaneous tumors. Veterinary and Comparative Oncology. https://doi.org/10.1111/vco.12844

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