02683-A: Treatment of Idiopathic Chronic Hepatitis and Copper Associated Hepatopathy in Dogs

Grant Status: Open

Grant Amount: $15,000
Sarah Shropshire, DVM, PhD; Colorado State University
January 1, 2020 - June 30, 2022

Sponsor(s): Bedlington Terrier Club of America

Breed(s): -All Dogs
Research Program Area: Hepatic Disease
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Abstract

This study will evaluate treatment regimens for two common and important liver diseases in dogs: idiopathic chronic hepatitis (ICH) and copper associated hepatopathy (CAH). Treatment of these diseases is essential to prevent progression to liver failure and death. At present, there are no standardized treatments for ICH or CAH in dogs. Dogs will be treated for ICH and CAH with two separate therapeutic regimens. The investigators will evaluate treatment efficacy by monitoring several hepatic parameters, including clinical signs, liver values, serum drug levels and copper levels. These parameters will be correlated to remission or relapse of disease to identify factors associated with treatment response. The findings of this project may significantly improve veterinarians’ ability to treat dogs with ICH and CAH.

Publication(s)

None at this time.

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