02681-A: Analysis of Canine Herpesvirus Isolates Using Next-Generation Sequencing

Grant Status: Closed

Grant Amount: $13,775
Andrew C. Lewin, BVM&S; Louisiana State University
January 1, 2020 - December 31, 2020

Sponsor(s): Irish Setter Club of America Foundation, Inc., Labrador Retriever Club, Inc.

Breed(s): -All Dogs
Research Program Area: Immunology and Infectious Disease
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Canine herpesvirus (CHV-1) is a common and serious disease of puppies and adult dogs. It is often fatal in puppies and can cause serious illness such as ocular disease, upper respiratory disease and vaginitis in adult dogs. This study will use cutting edge technology to determine the DNA sequence of canine herpesvirus isolates collected from dogs in the U.S. Sequenced DNA will be analyzed to study the virus at a genomic level and to highlight differences in viral genomes based on geographic location. This level of characterization will represent the largest work for CHV-1 worldwide to help prevent disease and inform novel therapeutic targets for treatment.


Lewin, A. C., Coghill, L. M., Mironovich, M., Liu, C.-C., Carter, R. T., & Ledbetter, E. C. (2020). Phylogenomic Analysis of Global Isolates of Canid Alphaherpesvirus 1. Viruses, 12(12), 1421. https://doi.org/10.3390/v12121421

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