Single Nucleotide Polymorphism (SNP)


Definition: A Single Nucleotide Polymorphism, or SNP (pronounced "snip"), is a small genetic change, or variation, that can occur within a person or animal's DNA sequence. The genetic code is specified by the four nucleotide "letters" A (adenine), C (cytosine), T (thymine), and G (guanine). SNP variation occurs when a single nucleotide, such as an A, replaces one of the other three nucleotide letters—C, G, or T.

Although many SNPs do not produce physical changes, scientists believe that other SNPs may predispose people and animals to disease and even influence their response to drug regimens.

This definition comes from the National Center for Biotechnology Information (NCBI).

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