00344-A: Tacrolimus 0.1% Ointment in the Treatment of Canine Familial Dermatomyositis

Grant Status: Closed

Grant Amount: $3,211.31
Dr. Christine Rees, DVM, Texas A&M University
October 1, 2004 - September 30, 2005
Breed(s): Shetland Sheepdog, Collie
Research Program Area: Treatment

Abstract

The goal of this pilot study is to determine whether tacrolimus 0.1% ointment would be beneficial (improvement of clinical signs) in the treatment of canine familial dermatomyositis (DM). A total of 8 dogs with clinical signs and biopsy findings which are consistent with DM will be included. Dogs will be monitored at monthly intervals for a three-month treatment period. Photographs, measurements and scoring of skin lesions will be taken during the initial visit and during each of the monthly recheck visits. A clinical scoring system will be used and the statistical significance between the before and after treatment scores will be determined. Bloodwork (complete blood counts and serum chemistries) and urinalysis will be performed at the beginning and at each of the monthly visits. Any changes in clinical pathology parameters will be noted.

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