Request For Research Pre-Proposals 2008 - 2009
Submission Deadline: March 3, 2008
Founded in 1995, the AKC Canine Health Foundation (www.akcchf.org) is the largest Foundation in the world focusing solely on canine health research and education. The Foundation provides significant resources for basic and applied health programs with an emphasis on canine genetics to improve the quality of life for dogs and their owners. We support scientists and professionals in research that concerns the origins of canine illness, diagnosis of canine diseases, development of effective treatments, and identification of disease prevention strategies.
Pre-Proposals
Pre-proposals for canine health research, both pre-clinical and clinical studies, in excess of $12,000 are now being accepted. These proposals are for 1 to 2 year projects (special dispensation may be approved for 3 year projects).
Full Applications
Pre-proposals will be evaluated and the Principal Investigator(s) will be notified of the selection of pre-proposals on or about April 1, 2008. Full Applications for approved pre-proposals are to be submitted by May 15, 2008. Additional information on submission of full applications will be provided to the PIs whose pre-proposals are approved. For one year projects, payments are made in three equal payments: upon grant initiation, at six months (upon receipt and approval of timely progress reports), and at the completion of year one. For two year projects, payments are made in five equal payments: upon initiation of grant, every six months (upon receipt and approval of timely progress reports), and upon completion at the end of year two. Progress reports are due on the same schedule. Payments are dependent on the timely submission and approval of progress reports.
GUIDELINES FOR RESEARCH PROPOSALS
Research- Major goals of the Foundation include funding projects that utilize new genetic resources such as the sequence of the canine genome, canine microarray, the SNP chip, developing improved molecular and diagnostic tools, and providing evidence-based information for breeding decisions. The Foundation is also interested in clinical research to improve the health of dogs, especially work that has potential for near term applicability and positive impact on canine health.
- Applicants – Proposals are sought from researchers representing a variety of disciplines including, but not limited to, veterinary clinicians/scientists, geneticists, and molecular biologists. Collaborative projects involving investigators from a variety of disciplines and/or institutions, including human health researchers, are encouraged.
- Significance – Proposals should include the incidence of the particular disease in specific breeds of dogs and/or the canine population in general. Researchers should also clearly articulate the potential impact of their proposed research on the health of dogs or the understanding of the basis of the canine disease being studied.
- Indirect Costs – These costs should be included for all proposed budgets for university or institution-based projects at a maximum level of 8%.
- Items Ineligible for Funding - CHF does not fund salaries of tenure-track or professional investigators/statisticians, purchase or repair of equipment, purchase of computers or software, custom software, tuition, travel to meetings, or purchase or transport of dogs (refer to complete and current list on our website, www.akcchf.org).
- Animal Use and Care – Investigations involving research animals must gain permission from their institutional animal care and use committee (IACUC) and comply with current institutional, USDA, or NIH Care and Use of Laboratory Animal guidelines. Funded projects must be performed in a manner that protects animals from any unnecessary pain. Funding will not be provided for procedures or experiments involving disease or injury induction and/or euthanasia of healthy dogs. In addition, CHF does not support the establishment or maintenance of research dog colonies.
- Breed Specific Research – The Foundation is interested in breed-specific proposals. The Foundation seeks financial support from breed clubs to help fund approved projects. Please see Areas of Specific Research Interest and Breed-Specific Interests on the website, www.akcchf.org.
RESEARCH PRE-PROPOSAL CONTENT GUIDELINES
Pre-proposals are less extensive versions of Full Applications, which outline the investigators objectives/aims, significance of the research and the costs involved.
Title Page
- Title of proposed study (must be different from ongoing or pending research)
- Name of Principal Investigator(s), phone, fax, email, institution, mailing address
- Requested direct costs per year in US dollars
- Requested indirect costs per year (not to exceed 8% of total direct costs) in US dollars
- Total costs (direct plus indirect) for term of grant (one or two years) in US dollars
- Signatures of PI(s)
Additional Pages
- Scientific Abstract – scientific summary of research in 200 words or less
- Lay Abstract - lay summary of research to be provided to breed club health liaisons
- Names of co-investigators, institutions, contact information
- Significance of research
- Background of research and preliminary work
- Specific Objectives: Clearly stated and different from ongoing or pending research. Specific Objectives are to be performed within the grant
timeframe; future research beyond the grant period may be described only as possible future studies or possible future impact.
- Brief description of research design, methods, and/or tools
- Expected outcomes and or potential application(s) to all dogs or specific breeds
- Anticipated problems or obstacles
- Biographical profiles for PI and co-investigators
- References
- Detailed budget estimates for each year. Budget should include the following categories (as appropriate):
- Salary for non-tenured, non-tenure track, non-professional investigators
- supplies and reagents (including microarray costs per sample/dog)
- Clinical tests
- Office supplies, publication preparation
- Travel to dog shows to collect samples
- Specific and total costs to dog owners participating in the research
- Project timeline that identifies intermediate project milestones with anticipated dates for specific objectives to be completed
- Current funding sources for research on related-research topics
- Pending funding sources for research on proposed topic and related-research topics
Indications of support from Parent Clubs may be included as additional pages;
one page per club.
RESEARCH PRE-PROPOSAL SUBMISSION DEADLINE
March 3, 2008
An electronic copy of the application should be:
Emailed to chfapply@akcchf.org
Or mailed to
AKC Canine Health Foundation
Attn: Christine Haakenson, PhD, Director, Research Program Development
P.O. Box 900061, Raleigh, NC 27675-9061 [for US Postal Service] or
8051 Arco Corporate Drive, Suite 300, Raleigh, NC 27617-3901 [for FedEX or other handlers]
Questions: Dr. Christine Haakenson, Director, Research Program Development, CLH@akcchf.org or Erika Werne, Director, Canine Research & Education, EAW@akcchf.org
1-888-682-9696
If you have question please
contact us.
