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RFP – Request for Research Pre-Proposals 2010

Submission Deadline: March 1, 2010

Pre-proposals for canine health research, both pre-clinical and clinical studies, in excess of $12,000, are now being accepted. These proposals are for 1 to 2 year projects (special dispensation may be made for 3 year projects). There is not a specified budget limit but note that the average approved grant in 2009 was $94,000 with a $57,000 standard deviation.

Pre-proposals will be evaluated and the Principal Investigator will be notified of the selection of pre-proposals by April 9, 2010. Full Applications for approved pre-proposals are to be submitted by May 15, 2010. Additional information on submission instructions for full applications will be provided to the PIs whose pre-proposals are approved. Funding decisions for the 2010 grant cycle will be made in September, 2010.

Pre-proposals will be selected based on:

  • Significance of health concern through the seriousness of the disease and the potential impact on the lives of dogs.
  • Research areas of interest for CHF and breed clubs.
  • Cost benefit of the study.
  • Scientific soundness of proposed methods. Detailed scientific review will occur if invited for full application.
  • Humane treatment of dogs with study participation only with the consent of the owners.
  • Investigator’s past performance with research projects and publications in peer-reviewed journals.
  • Current and future portfolio of CHF grants.

CHF will accept pre-proposals for all areas of canine health however there are specific areas for which CHF is seeking submissions. Go to CHF Research Interests for more information.

CHF also polls the breed clubs and breed enthusiasts for a list of the major health concerns for within the breeds. Go to Breed Specific Health Interests for more information.

Please forward this RFP to any of your colleagues who may be interested in applying for a CHF grant.

Proposals for less than $12,000 (ACORN grants) may be submitted throughout the year. For more information about these grants, go to the ACORN Information Page.

Notice for Genetic Researchers:
The CHIC DNA Repository has canine DNA samples available to genetic researchers. The CHIC DNA Repository, co-sponsored by OFA and CHF, collects and stores canine DNA samples along with corresponding genealogic and updated health information to facilitate future research and testing aimed at reducing the incidence of inherited disease in dogs. The goals of the CHIC DNA Repository are to:

  • Facilitate more rapid research progress by expediting the sample collection process
  • Provide researchers with optimized family groups needed for research
  • Foster a team environment between breeders/owners and the research community improving the likelihood of genetic discovery

Any genetic researcher may apply to have access to these samples and any CHF funded project is pre-approved this access.

The database for the CHIC DNA Repository has the capability to record the existence of DNA samples located at outside research institutions to assistance in collaboration between researchers. CHF requests that the existence of DNA samples collected with CHF funding be submitted to the CHIC DNA Repository upon completion of the research project and publication of the results.

Research Pre-Proposal Instructions

Please Note: The instructions for the Pre-Proposals have been modified. Please read them carefully and follow the directions. CHF Pre-Proposals are now being submitted online. Any applications submitted that do not follow the instructions will not be reviewed.

Pre-Proposal Content and Submission:
To submit an application you must completed a short form online and attach a PDF Research Proposal. The information entered online must match your proposal exactly.

1) Online Form – Required. Start a new application online at New CHF Pre-Proposal. If you are returning to work on a saved application, go to Continue CHF Applications. A tutorial presentation is available to help assist in using the online submission (click here.) Information to be entered in the online form includes:

  • Title of the proposed study
  • Research Organization
  • Principal Investigator
  • Co-Principle Investigator
  • Duration of the project in months
  • Total amount requested in US Dollars
  • Lay Abstract (limit to 250 words) - Statement of Research Problem and Objectives in lay language for public audiences

2) Study Pre-Proposal – Required. Upload PDF attachment to the online form. (limit to 5 pages – Be succinct)

An application template is available (click here.) Format information for the study pre-proposal is: Font Style: Arial or Times New Roman; Font Size: 12 pt; Margins: 1 inch

A. Cover Page

  • Title of the proposed study
  • Research Organization
  • Principal Investigator(s)
  • Indicate if the application is a resubmission or a continuation of currently funded research.
  • Duration of the project in months
  • Total amount requested in US Dollars
  • Lay Abstract (limit to 250 words) - Statement of Research Problem and Objectives in lay language for public audiences

B. Study Proposal

i. Statement of Purpose/Hypothesis/Objectives

  • Specific objectives (must be different from ongoing or pending research)

ii. Background of Proposed Research

  • Significance to Canine Health (If applicable, significance to specific breeds)
  • Brief Literature Review
  • Preliminary Studies - Description of preliminary data that supports the hypothesis. Please indicate if previous CHF funding was used to generate the data.

iii. Experimental Methods and Design

  • General description about methods to be used for each objective.

iv. Animals (limit 100 words)

  • Since CHF has restrictions on dogs used in research, please clearly indicate where the participating dogs and/or samples will be obtained. Specific treatment protocols for the animals should be included in the Experimental Methods and Design. CHF will not fund the purchase of dogs, dog research colonies, projects involving disease induction or injury models in dogs, or euthanasia of healthy dogs.

v. Expected outcome, significance and application of findings (limit 200 words)

C. List of Investigators

D. References

E. Budget Estimates

  • Cost Estimates based on the below categories
    • Salary (non-tenured, non-tenure track, non-professional investigators)
    • Supplies and Reagents
    • Clinical Tests
    • Sample Collection Expenses
    • Other (please specify)
    • Institutional Indirect Costs (Max of 8%)
  • CHF does not financially support the following:
    • Salary of tenure-track faculty (university) or professional, salaried senior-staff (non-profit or for-profit)
    • Laboratory equipment, repair or non-disposable parts
    • Computer equipment
    • Computer software
    • Development of custom-designed computer software
    • Tuition or registration fees for classes, training, or conferences
    • Travel expenses for any purpose, except those directly related to sample procurement (example: dog shows)
    • Transportation of dogs

3) Signature Page – Required. To submit an application you must attach a PDF Signature Page. Upload an one page PDF attachment to the online form which includes the signatures of the Principal Investigator(s) and the Organization's Grant Officer. This page should have much of the cover page information. A signature page application template is available (click here.)

  • Title of the proposed study
  • Research Organization
  • Principal Investigator(s)
  • Indicate if the application is a resubmission or a continuation of currently funded research.
  • Duration of the project in months
  • Total amount requested in US Dollars
  • Signatures

4) Recommendation Letters – Optional. Upload a single PDF attachment to the online form contained recommendation letters from Breed Clubs or co-investigators.

How To Submit

The Pre-proposal is due March 1, 2010. Start a new application online at New CHF Pre-Proposal. If you are returning to work on a saved application, go to Continue CHF Applications. A tutorial presentation is available to help assist in using the online submission (click here.)

Once your proposal is submitted, it cannot be changed. Please review and/or print before clicking “Submit.”

If you do not receive a confirmation email by 5 PM March 2, 2010, contact the office at 888-682-9696.

Questions:
Dr. Christine Haakenson, Director of Research
CLH@caninehealthfoundation.org, 1-888-682-9696
 
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