Medium-Chain Triglyceride Oil for the Treatment of Canine Epilepsy

05/27/2020

CHF Grant: 02252: Investigating a Ketogenic Medium-Chain Triglyceride (MCT) Supplement for the Treatment of Drug-Resistant Canine Idiopathic Epilepsy and Its Behavioral Comorbidities

Publication: Berk, B. A., Law, T. H., Packer, R. M. A., Wessmann, A., Bathen‐Nöthen, A., Jokinen, T. S., Knebel, A., Tipold, A., Pelligand, L., Meads, Z., & Volk, H. A. (2020). A multicenter randomized controlled trial of effect of medium-chain triglyceride dietary supplementation on epilepsy in dogs. Journal of Veterinary Internal Medicine, 1–2.
https://doi.org/10.1111/jvim.15756

What can we learn?
MCT oil is one component of the ketogenic diet, which has been shown to improve seizure control in people. Researchers at the Royal Veterinary College, University of London conducted a six month, multicenter, prospective, randomized, double‐blinded, placebo‐controlled crossover trial, comparing the use of a medium-chain triglyceride (MCT oil) supplement with a control supplement in the treatment of canine idiopathic epilepsy.

Conclusion - The MCT oil was well-tolerated and there was a statistically significant improvement in seizure control while dogs were taking the supplement. This was noted as a reduction in the total number of seizures reported each month and a reduction in the number of days each month in which a seizure occurred. MCT oil supplementation is a valid tool for use in the treatment of canine idiopathic epilepsy.

Read the full article here.

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